BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 23187686)

  • 41. Synthesis and structure-activity relationship of lipo-diterpenoid alkaloids with potential target of topoisomerase IIα for breast cancer treatment.
    Luan S; Gao Y; Liang X; Zhang L; Yin L; He C; Liu S; Yin Z; Yue G; Zou Y; Li L; Song X; Lv C; Zhang W; Jing B
    Bioorg Chem; 2021 Apr; 109():104699. PubMed ID: 33611138
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Oxocrebanine: A Novel Dual Topoisomerase inhibitor, Suppressed the Proliferation of Breast Cancer Cells MCF-7 by Inducing DNA Damage and Mitotic Arrest.
    Yu L; Han S; Lang L; Song H; Zhang C; Dong L; Jia S; Zhang Y; Xiao D; Liu J; Xu Y; Zhang X
    Phytomedicine; 2021 Apr; 84():153504. PubMed ID: 33611211
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
    Alam R; Wahi D; Singh R; Sinha D; Tandon V; Grover A; Rahisuddin
    Bioorg Chem; 2016 Dec; 69():77-90. PubMed ID: 27744115
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Discovery of new ATP-competitive inhibitors of human DNA topoisomerase IIα through screening of bacterial topoisomerase inhibitors.
    Skok Ž; Durcik M; Gramec Skledar D; Barančoková M; Peterlin Mašič L; Tomašič T; Zega A; Kikelj D; Zidar N; Ilaš J
    Bioorg Chem; 2020 Sep; 102():104049. PubMed ID: 32688116
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Precursor-Directed Generation of Indolocarbazoles with Topoisomerase IIα Inhibitory Activity.
    Wang C; Monger A; Wang L; Fu P; Piyachaturawat P; Chairoungdua A; Zhu W
    Mar Drugs; 2018 May; 16(5):. PubMed ID: 29772796
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
    Karki R; Park C; Jun KY; Kadayat TM; Lee ES; Kwon Y
    Eur J Med Chem; 2015 Jan; 90():360-78. PubMed ID: 25437622
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Design, synthesis, and cytotoxicity screening of 5-aryl-3-(2-(pyrrolyl) thiophenyl)-1, 2, 4-oxadiazoles as potential antitumor molecules on breast cancer MCF-7 cells.
    Abd El Hameid MK; Mohammed MR
    Bioorg Chem; 2019 May; 86():609-623. PubMed ID: 30807934
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
    Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
    Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.
    Tokala R; Mahajan S; Kiranmai G; Sigalapalli DK; Sana S; John SE; Nagesh N; Shankaraiah N
    Bioorg Chem; 2021 Jan; 106():104481. PubMed ID: 33261848
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis of friedelan triterpenoid analogs with DNA topoisomerase IIα inhibitory activity and their molecular docking studies.
    Mandal A; Ghosh S; Bothra AK; Nanda AK; Ghosh P
    Eur J Med Chem; 2012 Aug; 54():137-43. PubMed ID: 22633831
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Benzo[b]tryptanthrin inhibits MDR1, topoisomerase activity, and reverses adriamycin resistance in breast cancer cells.
    Jun KY; Park SE; Liang JL; Jahng Y; Kwon Y
    ChemMedChem; 2015 May; 10(5):827-35. PubMed ID: 25809558
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Computational screening of chalcones acting against topoisomerase IIα and their cytotoxicity towards cancer cell lines.
    Sangpheak K; Mueller M; Darai N; Wolschann P; Suwattanasophon C; Ruga R; Chavasiri W; Seetaha S; Choowongkomon K; Kungwan N; Rungnim C; Rungrotmongkol T
    J Enzyme Inhib Med Chem; 2019 Dec; 34(1):134-143. PubMed ID: 30394113
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Novel DNA topoisomerase IIα inhibitors from combined ligand- and structure-based virtual screening.
    Drwal MN; Marinello J; Manzo SG; Wakelin LP; Capranico G; Griffith R
    PLoS One; 2014; 9(12):e114904. PubMed ID: 25489853
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Pyrroloquinolinone-based dual topoisomerase I/II inhibitor.
    Dalla Via L; Marzaro G; Ferrarese A; Gia O; Chilin A
    Eur J Med Chem; 2014 Apr; 77():103-9. PubMed ID: 24631729
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
    Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα.
    Loboda KB; Valjavec K; Štampar M; Wolber G; Žegura B; Filipič M; Dolenc MS; Perdih A
    Bioorg Chem; 2020 Jun; 99():103828. PubMed ID: 32315896
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Design and Discovery of Novel Quinoxaline Derivatives as Dual DNA Intercalators and Topoisomerase II Inhibitors.
    Eissa IH; El-Naggar AM; El-Sattar NEAA; Youssef ASA
    Anticancer Agents Med Chem; 2018; 18(2):195-209. PubMed ID: 28699490
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors.
    Arepalli SK; Lee C; Sim S; Lee K; Jo H; Jun KY; Kwon Y; Kang JS; Jung JK; Lee H
    Bioorg Med Chem; 2018 Oct; 26(18):5181-5193. PubMed ID: 30253887
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors.
    de Camargo MS; De Grandis RA; da Silva MM; da Silva PB; Santoni MM; Eismann CE; Menegário AA; Cominetti MR; Zanelli CF; Pavan FR; Batista AA
    Biometals; 2019 Feb; 32(1):89-100. PubMed ID: 30506342
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Synthesis and biological evaluation of benzo[a]phenazine derivatives as a dual inhibitor of topoisomerase I and II.
    Zhuo ST; Li CY; Hu MH; Chen SB; Yao PF; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
    Org Biomol Chem; 2013 Jun; 11(24):3989-4005. PubMed ID: 23657605
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.