These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

314 related articles for article (PubMed ID: 23188716)

  • 1. Targeting the metastasis suppressor, NDRG1, using novel iron chelators: regulation of stress fiber-mediated tumor cell migration via modulation of the ROCK1/pMLC2 signaling pathway.
    Sun J; Zhang D; Zheng Y; Zhao Q; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2013 Feb; 83(2):454-69. PubMed ID: 23188716
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling.
    Wangpu X; Lu J; Xi R; Yue F; Sahni S; Park KC; Menezes S; Huang ML; Zheng M; Kovacevic Z; Richardson DR
    Mol Pharmacol; 2016 May; 89(5):521-40. PubMed ID: 26895766
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy.
    Fang BA; Kovačević Ž; Park KC; Kalinowski DS; Jansson PJ; Lane DJ; Sahni S; Richardson DR
    Biochim Biophys Acta; 2014 Jan; 1845(1):1-19. PubMed ID: 24269900
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metastasis suppressor, N-myc downstream-regulated gene 1 (NDRG1), inhibits stress-induced autophagy in cancer cells.
    Sahni S; Bae DH; Lane DJ; Kovacevic Z; Kalinowski DS; Jansson PJ; Richardson DR
    J Biol Chem; 2014 Apr; 289(14):9692-709. PubMed ID: 24532803
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).
    Chen Z; Zhang D; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Biol Chem; 2012 May; 287(21):17016-17028. PubMed ID: 22453918
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Metastasis Suppressor, N-MYC Downstream-regulated Gene-1 (NDRG1), Down-regulates the ErbB Family of Receptors to Inhibit Downstream Oncogenic Signaling Pathways.
    Kovacevic Z; Menezes SV; Sahni S; Kalinowski DS; Bae DH; Lane DJ; Richardson DR
    J Biol Chem; 2016 Jan; 291(3):1029-52. PubMed ID: 26534963
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Iron chelator-induced up-regulation of Ndrg1 inhibits proliferation and EMT process by targeting Wnt/β-catenin pathway in colon cancer cells.
    Chen Z; Sun J; Li T; Liu Y; Gao S; Zhi X; Zheng M
    Biochem Biophys Res Commun; 2018 Nov; 506(1):114-121. PubMed ID: 30340826
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.
    Sahni S; Park KC; Kovacevic Z; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1361-1378. PubMed ID: 30763642
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response.
    Merlot AM; Porter GM; Sahni S; Lim EG; Peres P; Richardson DR
    Biochim Biophys Acta Mol Basis Dis; 2019 Sep; 1865(9):2094-2110. PubMed ID: 30981813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of NDRG1 in the pathology and potential treatment of human cancers.
    Bae DH; Jansson PJ; Huang ML; Kovacevic Z; Kalinowski D; Lee CS; Sahni S; Richardson DR
    J Clin Pathol; 2013 Nov; 66(11):911-7. PubMed ID: 23750037
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways.
    Kovacevic Z; Chikhani S; Lui GY; Sivagurunathan S; Richardson DR
    Antioxid Redox Signal; 2013 Mar; 18(8):874-87. PubMed ID: 22462691
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel Thiosemicarbazones Inhibit Lysine-Rich Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) Coisolated (LYRIC) and the LYRIC-Induced Epithelial-Mesenchymal Transition via Upregulation of N-Myc Downstream-Regulated Gene 1 (NDRG1).
    Xi R; Pun IH; Menezes SV; Fouani L; Kalinowski DS; Huang ML; Zhang X; Richardson DR; Kovacevic Z
    Mol Pharmacol; 2017 May; 91(5):499-517. PubMed ID: 28275050
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The metastasis suppressor NDRG1 modulates the phosphorylation and nuclear translocation of β-catenin through mechanisms involving FRAT1 and PAK4.
    Jin R; Liu W; Menezes S; Yue F; Zheng M; Kovacevic Z; Richardson DR
    J Cell Sci; 2014 Jul; 127(Pt 14):3116-30. PubMed ID: 24829151
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer.
    Park KC; Paluncic J; Kovacevic Z; Richardson DR
    Free Radic Biol Med; 2020 Sep; 157():154-175. PubMed ID: 31132412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors.
    Sun J; Zhang D; Bae DH; Sahni S; Jansson P; Zheng Y; Zhao Q; Yue F; Zheng M; Kovacevic Z; Richardson DR
    Carcinogenesis; 2013 Sep; 34(9):1943-54. PubMed ID: 23671130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1.
    Liu W; Yue F; Zheng M; Merlot A; Bae DH; Huang M; Lane D; Jansson P; Lui GY; Richardson V; Sahni S; Kalinowski D; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Apr; 6(11):8851-74. PubMed ID: 25860930
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway.
    Ren K; Jin H; Bian C; He H; Liu X; Zhang S; Wang Y; Shao RG
    J Biol Chem; 2008 Dec; 283(51):35598-605. PubMed ID: 18948272
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types.
    Moussa RS; Kovacevic Z; Richardson DR
    Oncotarget; 2015 Oct; 6(30):29694-711. PubMed ID: 26335183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities.
    Patel RA; Liu Y; Wang B; Li R; Sebti SM
    Oncogene; 2014 Jan; 33(5):550-5. PubMed ID: 23396364
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor N-myc down-stream regulated gene 1: a new strategy for the treatment of pancreatic cancer.
    Kovacevic Z; Chikhani S; Lovejoy DB; Richardson DR
    Mol Pharmacol; 2011 Oct; 80(4):598-609. PubMed ID: 21719465
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.