BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 23190604)

  • 1. ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced apoptosis in glioblastoma cells.
    Cristofanon S; Fulda S
    Cell Death Dis; 2012 Nov; 3(11):e432. PubMed ID: 23190604
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis.
    Unterkircher T; Cristofanon S; Vellanki SH; Nonnenmacher L; Karpel-Massler G; Wirtz CR; Debatin KM; Fulda S
    Clin Cancer Res; 2011 Jun; 17(12):4019-30. PubMed ID: 21525171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S; Sinicrope FA
    Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines.
    Premkumar DR; Jane EP; DiDomenico JD; Vukmer NA; Agostino NR; Pollack IF
    J Pharmacol Exp Ther; 2012 Jun; 341(3):859-72. PubMed ID: 22393246
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.
    Foster KA; Jane EP; Premkumar DR; Morales A; Pollack IF
    J Neurooncol; 2014 Dec; 120(3):459-72. PubMed ID: 25139025
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cleavage by Caspase 8 and Mitochondrial Membrane Association Activate the BH3-only Protein Bid during TRAIL-induced Apoptosis.
    Huang K; Zhang J; O'Neill KL; Gurumurthy CB; Quadros RM; Tu Y; Luo X
    J Biol Chem; 2016 May; 291(22):11843-51. PubMed ID: 27053107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sensitization of glioblastoma cells to TRAIL-induced apoptosis by IAP- and Bcl-2 antagonism.
    Lincoln FA; Imig D; Boccellato C; Juric V; Noonan J; Kontermann RE; Allgöwer F; Murphy BM; Rehm M
    Cell Death Dis; 2018 Nov; 9(11):1112. PubMed ID: 30385739
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway.
    Naumann I; Kappler R; von Schweinitz D; Debatin KM; Fulda S
    Clin Cancer Res; 2011 May; 17(10):3204-18. PubMed ID: 21459798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of phosphatidylinositol 3-kinase/AKT signaling by NVP-BKM120 promotes ABT-737-induced toxicity in a caspase-dependent manner through mitochondrial dysfunction and DNA damage response in established and primary cultured glioblastoma cells.
    Jane EP; Premkumar DR; Morales A; Foster KA; Pollack IF
    J Pharmacol Exp Ther; 2014 Jul; 350(1):22-35. PubMed ID: 24741074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.
    Song JH; Kandasamy K; Kraft AS
    J Biol Chem; 2008 Sep; 283(36):25003-13. PubMed ID: 18599488
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mitochondrial fragmentation and neuronal cell death in response to the Bcl-2/Bcl-x(L)/Bcl-w antagonist ABT-737.
    Young KW; Piñón LG; Dhiraj D; Twiddy D; Macfarlane M; Hickman J; Nicotera P
    Neuropharmacology; 2010 Jun; 58(8):1258-67. PubMed ID: 20307556
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
    Hikita H; Takehara T; Kodama T; Shimizu S; Hosui A; Miyagi T; Tatsumi T; Ishida H; Ohkawa K; Li W; Kanto T; Hiramatsu N; Hennighausen L; Yin XM; Hayashi N
    Hepatology; 2009 Dec; 50(6):1972-80. PubMed ID: 19839062
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
    Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sensitization of tumor cells to Apo2 ligand/TRAIL-induced apoptosis by inhibition of casein kinase II.
    Ravi R; Bedi A
    Cancer Res; 2002 Aug; 62(15):4180-5. PubMed ID: 12154014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.
    Bangert A; Cristofanon S; Eckhardt I; Abhari BA; Kolodziej S; Häcker S; Vellanki SH; Lausen J; Debatin KM; Fulda S
    Oncogene; 2012 Nov; 31(44):4677-88. PubMed ID: 22266862
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Apoptosis-based treatment of glioblastomas with ABT-737, a novel small molecule inhibitor of Bcl-2 family proteins.
    Tagscherer KE; Fassl A; Campos B; Farhadi M; Kraemer A; Böck BC; Macher-Goeppinger S; Radlwimmer B; Wiestler OD; Herold-Mende C; Roth W
    Oncogene; 2008 Nov; 27(52):6646-56. PubMed ID: 18663354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
    Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax.
    Berger A; Quast SA; Plötz M; Kammermeier A; Eberle J
    Cell Death Dis; 2013 Jan; 4(1):e477. PubMed ID: 23348591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.
    Sutton VR; Sedelies K; Dewson G; Christensen ME; Bird PI; Johnstone RW; Kluck RM; Trapani JA; Waterhouse NJ
    Cell Death Dis; 2012 Jul; 3(7):e344. PubMed ID: 22764103
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
    Deng Y; Lin Y; Wu X
    Genes Dev; 2002 Jan; 16(1):33-45. PubMed ID: 11782443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.