These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 23193277)

  • 1. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response.
    Jullien L; Mestre M; Roux P; Gire V
    Nucleic Acids Res; 2013 Jan; 41(2):900-11. PubMed ID: 23193277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion.
    Celli GB; de Lange T
    Nat Cell Biol; 2005 Jul; 7(7):712-8. PubMed ID: 15968270
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A critical role for Pin2/TRF1 in ATM-dependent regulation. Inhibition of Pin2/TRF1 function complements telomere shortening, radiosensitivity, and the G(2)/M checkpoint defect of ataxia-telangiectasia cells.
    Kishi S; Lu KP
    J Biol Chem; 2002 Mar; 277(9):7420-9. PubMed ID: 11744712
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
    Denchi EL; de Lange T
    Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2.
    Dimitrova N; de Lange T
    Mol Cell Biol; 2009 Oct; 29(20):5552-63. PubMed ID: 19667071
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.
    Martínez P; Flores JM; Blasco MA
    J Cell Biol; 2012 Apr; 197(2):283-300. PubMed ID: 22508511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest.
    Hayashi MT; Cesare AJ; Fitzpatrick JA; Lazzerini-Denchi E; Karlseder J
    Nat Struct Mol Biol; 2012 Mar; 19(4):387-94. PubMed ID: 22407014
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres.
    Xu L; Blackburn EH
    Mol Cell; 2007 Oct; 28(2):315-27. PubMed ID: 17964269
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.
    Guo X; Deng Y; Lin Y; Cosme-Blanco W; Chan S; He H; Yuan G; Brown EJ; Chang S
    EMBO J; 2007 Nov; 26(22):4709-19. PubMed ID: 17948054
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Telomeric plasmid induces human cancer cell dysfunction depending on ATM activity.
    Guo XF; Cao EH
    Cell Biochem Funct; 2010 Jul; 28(5):381-6. PubMed ID: 20535839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATM/ATR checkpoint activation downregulates CDC25C to prevent mitotic entry with uncapped telomeres.
    Thanasoula M; Escandell JM; Suwaki N; Tarsounas M
    EMBO J; 2012 Aug; 31(16):3398-410. PubMed ID: 22842784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).
    Herbig U; Jobling WA; Chen BP; Chen DJ; Sedivy JM
    Mol Cell; 2004 May; 14(4):501-13. PubMed ID: 15149599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. p53 prevents entry into mitosis with uncapped telomeres.
    Thanasoula M; Escandell JM; Martinez P; Badie S; Muñoz P; Blasco MA; Tarsounas M
    Curr Biol; 2010 Mar; 20(6):521-6. PubMed ID: 20226664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.
    Zhang P; Furukawa K; Opresko PL; Xu X; Bohr VA; Mattson MP
    J Neurochem; 2006 Apr; 97(2):567-81. PubMed ID: 16539655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p53 governs telomere regulation feedback too, via TRF2.
    Horikawa I; Fujita K; Harris CC
    Aging (Albany NY); 2011 Jan; 3(1):26-32. PubMed ID: 21266744
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA damage checkpoint kinase Chk2 triggers replicative senescence.
    Gire V; Roux P; Wynford-Thomas D; Brondello JM; Dulic V
    EMBO J; 2004 Jul; 23(13):2554-63. PubMed ID: 15192702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA-damage response and repair activities at uncapped telomeres depend on RNF8.
    Peuscher MH; Jacobs JJ
    Nat Cell Biol; 2011 Aug; 13(9):1139-45. PubMed ID: 21857671
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response.
    Karlseder J; Hoke K; Mirzoeva OK; Bakkenist C; Kastan MB; Petrini JH; de Lange T
    PLoS Biol; 2004 Aug; 2(8):E240. PubMed ID: 15314656
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Apollo contributes to G overhang maintenance and protects leading-end telomeres.
    Wu P; van Overbeek M; Rooney S; de Lange T
    Mol Cell; 2010 Aug; 39(4):606-17. PubMed ID: 20619712
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Degradation of ATM-independent decatenation checkpoint function in human cells is secondary to inactivation of p53 and correlated with chromosomal destabilization.
    Kaufmann WK; Campbell CB; Simpson DA; Deming PB; Filatov L; Galloway DA; Zhao XJ; Creighton AM; Downes CS
    Cell Cycle; 2002; 1(3):210-9. PubMed ID: 12429935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.