216 related articles for article (PubMed ID: 23197651)
1. Polg2 is essential for mammalian embryogenesis and is required for mtDNA maintenance.
Humble MM; Young MJ; Foley JF; Pandiri AR; Travlos GS; Copeland WC
Hum Mol Genet; 2013 Mar; 22(5):1017-25. PubMed ID: 23197651
[TBL] [Abstract][Full Text] [Related]
2. Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA.
Wojtaszek JL; Hoff KE; Longley MJ; Kaur P; Andres SN; Wang H; Williams RS; Copeland WC
Nucleic Acids Res; 2023 Oct; 51(18):9716-9732. PubMed ID: 37592734
[TBL] [Abstract][Full Text] [Related]
3. Characterization of the human homozygous R182W POLG2 mutation in mitochondrial DNA depletion syndrome.
Hoff KE; DeBalsi KL; Sanchez-Quintero MJ; Longley MJ; Hirano M; Naini AB; Copeland WC
PLoS One; 2018; 13(8):e0203198. PubMed ID: 30157269
[TBL] [Abstract][Full Text] [Related]
4. Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis.
Hance N; Ekstrand MI; Trifunovic A
Hum Mol Genet; 2005 Jul; 14(13):1775-83. PubMed ID: 15888483
[TBL] [Abstract][Full Text] [Related]
5. Zebrafish polg2 knock-out recapitulates human POLG-disorders; implications for drug treatment.
Brañas Casas R; Zuppardo A; Risato G; Dinarello A; Celeghin R; Fontana C; Grelloni E; Gilea AI; Viscomi C; Rasola A; Dalla Valle L; Lodi T; Baruffini E; Facchinello N; Argenton F; Tiso N
Cell Death Dis; 2024 Apr; 15(4):281. PubMed ID: 38643274
[TBL] [Abstract][Full Text] [Related]
6. Whole exome sequencing identifies a homozygous POLG2 missense variant in an infant with fulminant hepatic failure and mitochondrial DNA depletion.
Varma H; Faust PL; Iglesias AD; Lagana SM; Wou K; Hirano M; DiMauro S; Mansukani MM; Hoff KE; Nagy PL; Copeland WC; Naini AB
Eur J Med Genet; 2016 Oct; 59(10):540-5. PubMed ID: 27592148
[TBL] [Abstract][Full Text] [Related]
7. Mutant POLG2 disrupts DNA polymerase gamma subunits and causes progressive external ophthalmoplegia.
Longley MJ; Clark S; Yu Wai Man C; Hudson G; Durham SE; Taylor RW; Nightingale S; Turnbull DM; Copeland WC; Chinnery PF
Am J Hum Genet; 2006 Jun; 78(6):1026-34. PubMed ID: 16685652
[TBL] [Abstract][Full Text] [Related]
8. POLG2 disease variants: analyses reveal a dominant negative heterodimer, altered mitochondrial localization and impaired respiratory capacity.
Young MJ; Humble MM; DeBalsi KL; Sun KY; Copeland WC
Hum Mol Genet; 2015 Sep; 24(18):5184-97. PubMed ID: 26123486
[TBL] [Abstract][Full Text] [Related]
9. Synergistic Effects of the
DeBalsi KL; Longley MJ; Hoff KE; Copeland WC
J Biol Chem; 2017 Mar; 292(10):4198-4209. PubMed ID: 28154168
[TBL] [Abstract][Full Text] [Related]
10. Defects in mitochondrial DNA replication and human disease.
Copeland WC
Crit Rev Biochem Mol Biol; 2012; 47(1):64-74. PubMed ID: 22176657
[TBL] [Abstract][Full Text] [Related]
11. Consequences of compromised mitochondrial genome integrity.
Gustafson MA; Sullivan ED; Copeland WC
DNA Repair (Amst); 2020 Sep; 93():102916. PubMed ID: 33087282
[TBL] [Abstract][Full Text] [Related]
12. POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts.
Stewart JD; Schoeler S; Sitarz KS; Horvath R; Hallmann K; Pyle A; Yu-Wai-Man P; Taylor RW; Samuels DC; Kunz WS; Chinnery PF
Biochim Biophys Acta; 2011 Mar; 1812(3):321-5. PubMed ID: 21138766
[TBL] [Abstract][Full Text] [Related]
13. Human mitochondrial DNA replication machinery and disease.
Young MJ; Copeland WC
Curr Opin Genet Dev; 2016 Jun; 38():52-62. PubMed ID: 27065468
[TBL] [Abstract][Full Text] [Related]
14. Mitochondrial DNA replication during differentiation of murine embryonic stem cells.
Facucho-Oliveira JM; Alderson J; Spikings EC; Egginton S; St John JC
J Cell Sci; 2007 Nov; 120(Pt 22):4025-34. PubMed ID: 17971411
[TBL] [Abstract][Full Text] [Related]
15. The accessory subunit of human DNA polymerase γ is required for mitochondrial DNA maintenance and is able to stabilize the catalytic subunit.
Do Y; Matsuda S; Inatomi T; Nakada K; Yasukawa T; Kang D
Mitochondrion; 2020 Jul; 53():133-139. PubMed ID: 32470614
[TBL] [Abstract][Full Text] [Related]
16. Damaged mitochondrial DNA replication system and the development of diabetic retinopathy.
Tewari S; Santos JM; Kowluru RA
Antioxid Redox Signal; 2012 Aug; 17(3):492-504. PubMed ID: 22229649
[TBL] [Abstract][Full Text] [Related]
17. A p.R369G POLG2 mutation associated with adPEO and multiple mtDNA deletions causes decreased affinity between polymerase γ subunits.
Craig K; Young MJ; Blakely EL; Longley MJ; Turnbull DM; Copeland WC; Taylor RW
Mitochondrion; 2012 Mar; 12(2):313-9. PubMed ID: 22155748
[TBL] [Abstract][Full Text] [Related]
18. Polymerase subunit gamma 2 affects porcine oocyte maturation and subsequent embryonic development.
Lee SK; Zhao MH; Zheng Z; Kwon JW; Liang S; Kim SH; Kim NH; Cui XS
Theriogenology; 2015 Jan; 83(1):121-30. PubMed ID: 25308052
[TBL] [Abstract][Full Text] [Related]
19. Whole exome sequencing identifies a homozygous POLG2 missense variant in an adult patient presenting with optic atrophy, movement disorders, premature ovarian failure and mitochondrial DNA depletion.
Dosekova P; Dubiel A; Karlowicz A; Zietkiewicz S; Rydzanicz M; Habalova V; Pienkowski VM; Skirkova M; Han V; Mosejova A; Gdovinova Z; Kaliszewska M; Tońska K; Szymanski MR; Skorvanek M; Ploski R
Eur J Med Genet; 2020 Apr; 63(4):103821. PubMed ID: 31778857
[TBL] [Abstract][Full Text] [Related]
20. Heterozygous p.Y955C mutation in DNA polymerase γ leads to alterations in bioenergetics, complex I subunit expression, and mtDNA replication.
Rahman MM; Young CKJ; Goffart S; Pohjoismäki JLO; Young MJ
J Biol Chem; 2022 Aug; 298(8):102196. PubMed ID: 35760101
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]