BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

215 related articles for article (PubMed ID: 23201008)

  • 1. Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
    Liu J; Xie YS; Wang FL; Zhang LJ; Zhang Y; Luo HS
    Biomed Pharmacother; 2013 Feb; 67(1):78-87. PubMed ID: 23201008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
    Liu J; Zhang Y; Xie YS; Wang FL; Zhang LJ; Deng T; Luo HS
    Oncol Rep; 2012 Aug; 28(2):545-52. PubMed ID: 22664909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
    Deng T; Zhang Y
    Life Sci; 2009 Feb; 84(9-10):311-20. PubMed ID: 19159630
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.
    Pulukuri SM; Rao JS
    Int J Oncol; 2005 Apr; 26(4):863-71. PubMed ID: 15753979
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.
    Karpf AR; Moore BC; Ririe TO; Jones DA
    Mol Pharmacol; 2001 Apr; 59(4):751-7. PubMed ID: 11259619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment.
    Wang H; Zhao Y; Li L; McNutt MA; Wu L; Lu S; Yu Y; Zhou W; Feng J; Chai G; Yang Y; Zhu WG
    J Biol Chem; 2008 Feb; 283(5):2564-74. PubMed ID: 17977830
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.
    Shin DY; Sung Kang H; Kim GY; Kim WJ; Yoo YH; Choi YH
    Biomed Pharmacother; 2013 May; 67(4):305-11. PubMed ID: 23582784
    [TBL] [Abstract][Full Text] [Related]  

  • 8. E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.
    Li Y; Shao J; Shen K; Xu Y; Liu J; Qian X
    J Cell Biochem; 2012 Oct; 113(10):3165-77. PubMed ID: 22593008
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells.
    Deng T; Zhang Y
    Biomed Pharmacother; 2009 Aug; 63(7):492-500. PubMed ID: 18848767
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines.
    Bender CM; Pao MM; Jones PA
    Cancer Res; 1998 Jan; 58(1):95-101. PubMed ID: 9426064
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.
    Zhu WG; Hileman T; Ke Y; Wang P; Lu S; Duan W; Dai Z; Tong T; Villalona-Calero MA; Plass C; Otterson GA
    J Biol Chem; 2004 Apr; 279(15):15161-6. PubMed ID: 14722112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.
    Palii SS; Van Emburgh BO; Sankpal UT; Brown KD; Robertson KD
    Mol Cell Biol; 2008 Jan; 28(2):752-71. PubMed ID: 17991895
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p53 signaling.
    Katsuyama M; Iwata K; Ibi M; Matsuno K; Matsumoto M; Yabe-Nishimura C
    Toxicology; 2012 Sep; 299(1):55-9. PubMed ID: 22627294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.
    Kumar A; Rai PS; Upadhya R; Vishwanatha ; Prasada KS; Rao BS; Satyamoorthy K
    Int J Radiat Biol; 2011 Nov; 87(11):1086-96. PubMed ID: 21815748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells.
    Qiu H; Yashiro M; Shinto O; Matsuzaki T; Hirakawa K
    Cancer Sci; 2009 Jan; 100(1):181-8. PubMed ID: 19037991
    [TBL] [Abstract][Full Text] [Related]  

  • 16. p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.
    Zheng QH; Ma LW; Zhu WG; Zhang ZY; Tong TJ
    J Cell Biochem; 2006 Aug; 98(5):1230-48. PubMed ID: 16514663
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).
    Momparler RL
    Semin Oncol; 2005 Oct; 32(5):443-51. PubMed ID: 16210084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors.
    Beyrouthy MJ; Garner KM; Hever MP; Freemantle SJ; Eastman A; Dmitrovsky E; Spinella MJ
    Cancer Res; 2009 Dec; 69(24):9360-6. PubMed ID: 19951990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.
    Zhu WG; Dai Z; Ding H; Srinivasan K; Hall J; Duan W; Villalona-Calero MA; Plass C; Otterson GA
    Oncogene; 2001 Nov; 20(53):7787-96. PubMed ID: 11753657
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line.
    Liu X; Dai X; Wu B
    Urol Int; 2009; 82(1):108-12. PubMed ID: 19172108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.