BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

817 related articles for article (PubMed ID: 23202730)

  • 21. Rheb GTPase regulates β-secretase levels and amyloid β generation.
    Shahani N; Pryor W; Swarnkar S; Kholodilov N; Thinakaran G; Burke RE; Subramaniam S
    J Biol Chem; 2014 Feb; 289(9):5799-808. PubMed ID: 24368770
    [TBL] [Abstract][Full Text] [Related]  

  • 22. BACE1: the beta-secretase enzyme in Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
    [TBL] [Abstract][Full Text] [Related]  

  • 23. BACE2 degradation mediated by the macroautophagy-lysosome pathway.
    Liu X; Wang Z; Wu Y; Wang J; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1970-7. PubMed ID: 23773066
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
    Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
    J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Presynaptic dystrophic neurites surrounding amyloid plaques are sites of microtubule disruption, BACE1 elevation, and increased Aβ generation in Alzheimer's disease.
    Sadleir KR; Kandalepas PC; Buggia-Prévot V; Nicholson DA; Thinakaran G; Vassar R
    Acta Neuropathol; 2016 Aug; 132(2):235-256. PubMed ID: 26993139
    [TBL] [Abstract][Full Text] [Related]  

  • 26. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
    Vassar R
    J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Altered amyloid-beta metabolism and deposition in genomic-based beta-secretase transgenic mice.
    Chiocco MJ; Kulnane LS; Younkin L; Younkin S; Evin G; Lamb BT
    J Biol Chem; 2004 Dec; 279(50):52535-42. PubMed ID: 15452128
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
    Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
    Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Beta-secretase-1 elevation in transgenic mouse models of Alzheimer's disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development.
    Zhang XM; Cai Y; Xiong K; Cai H; Luo XG; Feng JC; Clough RW; Struble RG; Patrylo PR; Yan XX
    Eur J Neurosci; 2009 Dec; 30(12):2271-83. PubMed ID: 20092570
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease.
    Rossner S; Sastre M; Bourne K; Lichtenthaler SF
    Prog Neurobiol; 2006 Jun; 79(2):95-111. PubMed ID: 16904810
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Melatonin ameliorates Aβ
    Chinchalongporn V; Shukla M; Govitrapong P
    J Pineal Res; 2018 May; 64(4):e12470. PubMed ID: 29352484
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid.
    Chen Y; Huang X; Zhang YW; Rockenstein E; Bu G; Golde TE; Masliah E; Xu H
    J Neurosci; 2012 Aug; 32(33):11390-5. PubMed ID: 22895721
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Aberrant proteolytic processing and therapeutic strategies in Alzheimer disease.
    Tomita T
    Adv Biol Regul; 2017 May; 64():33-38. PubMed ID: 28082052
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level.
    Sadleir KR; Eimer WA; Cole SL; Vassar R
    Mol Neurodegener; 2015 Jan; 10():1. PubMed ID: 25567526
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Acceleration of amyloidogenesis and memory impairment by estrogen deficiency through NF-κB dependent beta-secretase activation in presenilin 2 mutant mice.
    Hwang CJ; Park MH; Choi MK; Choi JS; Oh KW; Hwang DY; Han SB; Hong JT
    Brain Behav Immun; 2016 Mar; 53():113-122. PubMed ID: 26593275
    [TBL] [Abstract][Full Text] [Related]  

  • 36. FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylation.
    Bao XQ; Li N; Wang T; Kong XC; Tai WJ; Sun H; Zhang D
    PLoS One; 2013; 8(11):e78033. PubMed ID: 24223757
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
    Johnson ECB; Ho K; Yu GQ; Das M; Sanchez PE; Djukic B; Lopez I; Yu X; Gill M; Zhang W; Paz JT; Palop JJ; Mucke L
    Mol Neurodegener; 2020 Sep; 15(1):53. PubMed ID: 32921309
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Transcriptional and post-transcriptional regulation of β-secretase.
    Tamagno E; Guglielmotto M; Monteleone D; Vercelli A; Tabaton M
    IUBMB Life; 2012 Dec; 64(12):943-50. PubMed ID: 23180460
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Novel mutations introduced at the beta-site of amyloid beta protein precursor enhance the production of amyloid beta peptide by BACE1 in vitro and in cells.
    Shi XP; Tugusheva K; Bruce JE; Lucka A; Chen-Dodson E; Hu B; Wu GX; Price E; Register RB; Lineberger J; Miller R; Tang MJ; Espeseth A; Kahana J; Wolfe A; Crouthamel MC; Sankaranarayanan S; Simon A; Chen L; Lai MT; Pietrak B; DiMuzio J; Li Y; Xu M; Huang Q; Garsky V; Sardana MK; Hazuda DJ
    J Alzheimers Dis; 2005 Apr; 7(2):139-48; discussion 173-80. PubMed ID: 15851852
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Effects of Folic Acid on Secretases Involved in Aβ Deposition in APP/PS1 Mice.
    Tian T; Bai D; Li W; Huang GW; Liu H
    Nutrients; 2016 Sep; 8(9):. PubMed ID: 27618097
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 41.