These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 23209424)

  • 1. A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.
    Miller JP; Yates BE; Al-Ramahi I; Berman AE; Sanhueza M; Kim E; de Haro M; DeGiacomo F; Torcassi C; Holcomb J; Gafni J; Mooney SD; Botas J; Ellerby LM; Hughes RE
    PLoS Genet; 2012; 8(11):e1003042. PubMed ID: 23209424
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model.
    Schulte J; Sepp KJ; Wu C; Hong P; Littleton JT
    PLoS One; 2011; 6(8):e23841. PubMed ID: 21909362
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat.
    Clemens LE; Weber JJ; Wlodkowski TT; Yu-Taeger L; Michaud M; Calaminus C; Eckert SH; Gaca J; Weiss A; Magg JC; Jansson EK; Eckert GP; Pichler BJ; Bordet T; Pruss RM; Riess O; Nguyen HP
    Brain; 2015 Dec; 138(Pt 12):3632-53. PubMed ID: 26490331
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant huntingtin and glycogen synthase kinase 3-beta accumulate in neuronal lipid rafts of a presymptomatic knock-in mouse model of Huntington's disease.
    Valencia A; Reeves PB; Sapp E; Li X; Alexander J; Kegel KB; Chase K; Aronin N; DiFiglia M
    J Neurosci Res; 2010 Jan; 88(1):179-90. PubMed ID: 19642201
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model.
    Weiss KR; Kimura Y; Lee WC; Littleton JT
    Genetics; 2012 Feb; 190(2):581-600. PubMed ID: 22095086
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.
    Lu XH; Mattis VB; Wang N; Al-Ramahi I; van den Berg N; Fratantoni SA; Waldvogel H; Greiner E; Osmand A; Elzein K; Xiao J; Dijkstra S; de Pril R; Vinters HV; Faull R; Signer E; Kwak S; Marugan JJ; Botas J; Fischer DF; Svendsen CN; Munoz-Sanjuan I; Yang XW
    Sci Transl Med; 2014 Dec; 6(268):268ra178. PubMed ID: 25540325
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease.
    Miller JP; Holcomb J; Al-Ramahi I; de Haro M; Gafni J; Zhang N; Kim E; Sanhueza M; Torcassi C; Kwak S; Botas J; Hughes RE; Ellerby LM
    Neuron; 2010 Jul; 67(2):199-212. PubMed ID: 20670829
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.
    Zhang H; Li Q; Graham RK; Slow E; Hayden MR; Bezprozvanny I
    Neurobiol Dis; 2008 Jul; 31(1):80-8. PubMed ID: 18502655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.
    Jiang M; Wang J; Fu J; Du L; Jeong H; West T; Xiang L; Peng Q; Hou Z; Cai H; Seredenina T; Arbez N; Zhu S; Sommers K; Qian J; Zhang J; Mori S; Yang XW; Tamashiro KL; Aja S; Moran TH; Luthi-Carter R; Martin B; Maudsley S; Mattson MP; Cichewicz RH; Ross CA; Holtzman DM; Krainc D; Duan W
    Nat Med; 2011 Dec; 18(1):153-8. PubMed ID: 22179319
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons.
    Thomas EA; Coppola G; Tang B; Kuhn A; Kim S; Geschwind DH; Brown TB; Luthi-Carter R; Ehrlich ME
    Hum Mol Genet; 2011 Mar; 20(6):1049-60. PubMed ID: 21177255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum.
    Grondin R; Kaytor MD; Ai Y; Nelson PT; Thakker DR; Heisel J; Weatherspoon MR; Blum JL; Burright EN; Zhang Z; Kaemmerer WF
    Brain; 2012 Apr; 135(Pt 4):1197-209. PubMed ID: 22252996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Large-scale functional RNAi screen in C. elegans identifies genes that regulate the dysfunction of mutant polyglutamine neurons.
    Lejeune FX; Mesrob L; Parmentier F; Bicep C; Vazquez-Manrique RP; Parker JA; Vert JP; Tourette C; Neri C
    BMC Genomics; 2012 Mar; 13():91. PubMed ID: 22413862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
    Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
    Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes.
    Song H; Li H; Guo S; Pan Y; Fu Y; Zhou Z; Li Z; Wen X; Sun X; He B; Gu H; Zhao Q; Wang C; An P; Luo S; Hu Y; Xie X; Lu B
    Brain; 2018 Jun; 141(6):1782-1798. PubMed ID: 29608652
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice.
    Apostol BL; Simmons DA; Zuccato C; Illes K; Pallos J; Casale M; Conforti P; Ramos C; Roarke M; Kathuria S; Cattaneo E; Marsh JL; Thompson LM
    Mol Cell Neurosci; 2008 Sep; 39(1):8-20. PubMed ID: 18602275
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nature and cause of mitochondrial dysfunction in Huntington's disease: focusing on huntingtin and the striatum.
    Oliveira JM
    J Neurochem; 2010 Jul; 114(1):1-12. PubMed ID: 20403078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation.
    Behrens PF; Franz P; Woodman B; Lindenberg KS; Landwehrmeyer GB
    Brain; 2002 Aug; 125(Pt 8):1908-22. PubMed ID: 12135980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Loss of huntingtin function slows synaptic vesicle endocytosis in striatal neurons from the htt
    McAdam RL; Morton A; Gordon SL; Alterman JF; Khvorova A; Cousin MA; Smillie KJ
    Neurobiol Dis; 2020 Feb; 134():104637. PubMed ID: 31614197
    [TBL] [Abstract][Full Text] [Related]  

  • 19. VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease.
    Guo X; Qi X
    Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):552-559. PubMed ID: 27913212
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of Rhes, Ras homolog enriched in striatum, in neurodegenerative processes.
    Harrison LM; Lahoste GJ
    Exp Cell Res; 2013 Sep; 319(15):2310-5. PubMed ID: 23583659
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.