294 related articles for article (PubMed ID: 23209849)
1. Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign.
Sykes ML; Baell JB; Kaiser M; Chatelain E; Moawad SR; Ganame D; Ioset JR; Avery VM
PLoS Negl Trop Dis; 2012; 6(11):e1896. PubMed ID: 23209849
[TBL] [Abstract][Full Text] [Related]
2. A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes.
De Rycker M; O'Neill S; Joshi D; Campbell L; Gray DW; Fairlamb AH
PLoS Negl Trop Dis; 2012; 6(11):e1932. PubMed ID: 23209868
[TBL] [Abstract][Full Text] [Related]
3. Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.
Sykes ML; Avery VM
Am J Trop Med Hyg; 2009 Oct; 81(4):665-74. PubMed ID: 19815884
[TBL] [Abstract][Full Text] [Related]
4. Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei.
Faria J; Moraes CB; Song R; Pascoalino BS; Lee N; Siqueira-Neto JL; Cruz DJ; Parkinson T; Ioset JR; Cordeiro-da-Silva A; Freitas-Junior LH
J Biomol Screen; 2015 Jan; 20(1):70-81. PubMed ID: 25342146
[TBL] [Abstract][Full Text] [Related]
5. Whole-organism high-throughput screening against Trypanosoma brucei brucei.
Jones AJ; Avery VM
Expert Opin Drug Discov; 2013 May; 8(5):495-507. PubMed ID: 23540598
[TBL] [Abstract][Full Text] [Related]
6. 3-(Oxazolo[4,5-b]pyridin-2-yl)anilides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei, the causative agent for human African trypanosomiasis.
Ferrins L; Rahmani R; Sykes ML; Jones AJ; Avery VM; Teston E; Almohaywi B; Yin J; Smith J; Hyland C; White KL; Ryan E; Campbell M; Charman SA; Kaiser M; Baell JB
Eur J Med Chem; 2013 Aug; 66():450-65. PubMed ID: 23831695
[TBL] [Abstract][Full Text] [Related]
7. A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.
Sykes ML; Avery VM
Parasit Vectors; 2009 Nov; 2(1):54. PubMed ID: 19909542
[TBL] [Abstract][Full Text] [Related]
8. Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.
Navarro G; Chokpaiboon S; De Muylder G; Bray WM; Nisam SC; McKerrow JH; Pudhom K; Linington RG
PLoS One; 2012; 7(9):e46172. PubMed ID: 23029428
[TBL] [Abstract][Full Text] [Related]
9. Identification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis.
Jones AJ; Kaiser M; Avery VM
Antimicrob Agents Chemother; 2015 Dec; 60(3):1859-61. PubMed ID: 26666915
[TBL] [Abstract][Full Text] [Related]
10. Development of resazurin-based assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei rhodesiense strain STIB 900 for the identification of potential anti-trypanosomal agents.
Lim KT; Zahari Z; Amanah A; Zainuddin Z; Adenan MI
Exp Parasitol; 2016 Mar; 162():49-56. PubMed ID: 26772786
[TBL] [Abstract][Full Text] [Related]
11. Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.
Pedró-Rosa L; Buckner FS; Ranade RM; Eberhart C; Madoux F; Gillespie JR; Koh CY; Brown S; Lohse J; Verlinde CL; Fan E; Bannister T; Scampavia L; Hol WG; Spicer T; Hodder P
J Biomol Screen; 2015 Jan; 20(1):122-30. PubMed ID: 25163684
[TBL] [Abstract][Full Text] [Related]
12. Identification of Trypanosoma brucei AdoMetDC Inhibitors Using a High-Throughput Mass Spectrometry-Based Assay.
Volkov OA; Cosner CC; Brockway AJ; Kramer M; Booker M; Zhong S; Ketcherside A; Wei S; Longgood J; McCoy M; Richardson TE; Wring SA; Peel M; Klinger JD; Posner BA; De Brabander JK; Phillips MA
ACS Infect Dis; 2017 Jul; 3(7):512-526. PubMed ID: 28350440
[TBL] [Abstract][Full Text] [Related]
13. Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei.
Mackey ZB; Baca AM; Mallari JP; Apsel B; Shelat A; Hansell EJ; Chiang PK; Wolff B; Guy KR; Williams J; McKerrow JH
Chem Biol Drug Des; 2006 May; 67(5):355-63. PubMed ID: 16784460
[TBL] [Abstract][Full Text] [Related]
14. 6-Arylpyrazine-2-carboxamides: A New Core for Trypanosoma brucei Inhibitors.
Rahmani R; Ban K; Jones AJ; Ferrins L; Ganame D; Sykes ML; Avery VM; White KL; Ryan E; Kaiser M; Charman SA; Baell JB
J Med Chem; 2015 Sep; 58(17):6753-65. PubMed ID: 26247439
[TBL] [Abstract][Full Text] [Related]
15. Antitrypanosomal activity of some medicinal plants from Nigerian ethnomedicine.
Abiodun OO; Gbotosho GO; Ajaiyeoba EO; Brun R; Oduola AM
Parasitol Res; 2012 Feb; 110(2):521-6. PubMed ID: 21789586
[TBL] [Abstract][Full Text] [Related]
16. Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.
Diaz R; Luengo-Arratta SA; Seixas JD; Amata E; Devine W; Cordon-Obras C; Rojas-Barros DI; Jimenez E; Ortega F; Crouch S; Colmenarejo G; Fiandor JM; Martin JJ; Berlanga M; Gonzalez S; Manzano P; Navarro M; Pollastri MP
PLoS Negl Trop Dis; 2014 Oct; 8(10):e3253. PubMed ID: 25340575
[TBL] [Abstract][Full Text] [Related]
17. Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs.
Nnadi CO; Ebiloma GU; Black JA; Nwodo NJ; Lemgruber L; Schmidt TJ; de Koning HP
Molecules; 2019 Jan; 24(2):. PubMed ID: 30642032
[TBL] [Abstract][Full Text] [Related]
18. Screening of acyl hydrazide proteinase inhibitors for antiparasitic activity against Trypanosoma brucei.
Caffrey CR; Schanz M; Nkemngu NJ; Brush M; Hansell E; Cohen FE; Flaherty TM; McKerrow JH; Steverding D
Int J Antimicrob Agents; 2002 Mar; 19(3):227-31. PubMed ID: 11932146
[TBL] [Abstract][Full Text] [Related]
19. Novel aroyl guanidine anti-trypanosomal compounds that exert opposing effects on parasite energy metabolism.
Varghese S; Srivastava A; Wong SW; Le T; Pitcher N; Mesnard M; Lallemand C; Rahmani R; Moawad SR; Huang F; He T; Sleebs BE; Barrett MP; Sykes ML; Avery VM; Creek DJ; Baell JB
Eur J Med Chem; 2024 Mar; 268():116162. PubMed ID: 38394930
[TBL] [Abstract][Full Text] [Related]
20. Cynaropicrin: the first plant natural product with in vivo activity against Trypanosoma brucei.
Zimmermann S; Kaiser M; Brun R; Hamburger M; Adams M
Planta Med; 2012 Apr; 78(6):553-6. PubMed ID: 22331812
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
