282 related articles for article (PubMed ID: 23209944)
1. Development of safer gene delivery systems to minimize the risk of insertional mutagenesis-related malignancies: a critical issue for the field of gene therapy.
Romano G
ISRN Oncol; 2012; 2012():616310. PubMed ID: 23209944
[TBL] [Abstract][Full Text] [Related]
2. Insertional mutagenesis and development of malignancies induced by integrating gene delivery systems: implications for the design of safer gene-based interventions in patients.
Romano G; Marino IR; Pentimalli F; Adamo V; Giordano A
Drug News Perspect; 2009 May; 22(4):185-96. PubMed ID: 19536363
[TBL] [Abstract][Full Text] [Related]
3. Adeno-associated virus Rep-mediated targeting of integrase-defective retroviral vector DNA circles into human chromosome 19.
Huang S; Kawabe Y; Ito A; Kamihira M
Biochem Biophys Res Commun; 2012 Jan; 417(1):78-83. PubMed ID: 22138242
[TBL] [Abstract][Full Text] [Related]
4. Germline mutagenesis mediated by Sleeping Beauty transposon system in mice.
Takeda J; Keng VW; Horie K
Genome Biol; 2007; 8 Suppl 1(Suppl 1):S14. PubMed ID: 18047691
[TBL] [Abstract][Full Text] [Related]
5. Monitoring for potential adverse effects of prenatal gene therapy: genotoxicity analysis in vitro and on small animal models ex vivo and in vivo.
Themis M
Methods Mol Biol; 2012; 891():341-70. PubMed ID: 22648780
[TBL] [Abstract][Full Text] [Related]
6. Stem cell gene therapy: the risks of insertional mutagenesis and approaches to minimize genotoxicity.
Wu C; Dunbar CE
Front Med; 2011 Dec; 5(4):356-71. PubMed ID: 22198747
[TBL] [Abstract][Full Text] [Related]
7. Hybrid lentivirus-transposon vectors with a random integration profile in human cells.
Staunstrup NH; Moldt B; Mátés L; Villesen P; Jakobsen M; Ivics Z; Izsvák Z; Mikkelsen JG
Mol Ther; 2009 Jul; 17(7):1205-14. PubMed ID: 19240688
[TBL] [Abstract][Full Text] [Related]
8. Translating Sleeping Beauty transposition into cellular therapies: victories and challenges.
Izsvák Z; Hackett PB; Cooper LJ; Ivics Z
Bioessays; 2010 Sep; 32(9):756-67. PubMed ID: 20652893
[TBL] [Abstract][Full Text] [Related]
9. [Development and application of gene therapy technologies].
Ozawa K
Uirusu; 2004 Jun; 54(1):49-57. PubMed ID: 15449904
[TBL] [Abstract][Full Text] [Related]
10. Stable transgene expression in primitive human CD34+ hematopoietic stem/progenitor cells, using the Sleeping Beauty transposon system.
Sumiyoshi T; Holt NG; Hollis RP; Ge S; Cannon PM; Crooks GM; Kohn DB
Hum Gene Ther; 2009 Dec; 20(12):1607-26. PubMed ID: 19689196
[TBL] [Abstract][Full Text] [Related]
11. Parachuting in the epigenome: the biology of gene vector insertion profiles in the context of clinical trials.
Baum C
EMBO Mol Med; 2011 Feb; 3(2):75-7. PubMed ID: 21254403
[TBL] [Abstract][Full Text] [Related]
12. The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery.
Anson DS
Genet Vaccines Ther; 2004 Aug; 2(1):9. PubMed ID: 15310406
[TBL] [Abstract][Full Text] [Related]
13. Transgenesis in Xenopus using the Sleeping Beauty transposon system.
Yergeau DA; Johnson Hamlet MR; Kuliyev E; Zhu H; Doherty JR; Archer TD; Subhawong AP; Valentine MB; Kelley CM; Mead PE
Dev Dyn; 2009 Jul; 238(7):1727-43. PubMed ID: 19517568
[TBL] [Abstract][Full Text] [Related]
14. Stable gene transfer to human CD34(+) hematopoietic cells using the Sleeping Beauty transposon.
Hollis RP; Nightingale SJ; Wang X; Pepper KA; Yu XJ; Barsky L; Crooks GM; Kohn DB
Exp Hematol; 2006 Oct; 34(10):1333-43. PubMed ID: 16982326
[TBL] [Abstract][Full Text] [Related]
15. Development of the hybrid Sleeping Beauty: baculovirus vector for sustained gene expression and cancer therapy.
Luo WY; Shih YS; Hung CL; Lo KW; Chiang CS; Lo WH; Huang SF; Wang SC; Yu CF; Chien CH; Hu YC
Gene Ther; 2012 Aug; 19(8):844-51. PubMed ID: 21918552
[TBL] [Abstract][Full Text] [Related]
16. Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors.
Holstein M; Mesa-Nuñez C; Miskey C; Almarza E; Poletti V; Schmeer M; Grueso E; Ordóñez Flores JC; Kobelt D; Walther W; Aneja MK; Geiger J; Bonig HB; Izsvák Z; Schleef M; Rudolph C; Mavilio F; Bueren JA; Guenechea G; Ivics Z
Mol Ther; 2018 Apr; 26(4):1137-1153. PubMed ID: 29503198
[TBL] [Abstract][Full Text] [Related]
17. Sleeping Beauty-baculovirus hybrid vectors for long-term gene expression in the eye.
Turunen TA; Laakkonen JP; Alasaarela L; Airenne KJ; Ylä-Herttuala S
J Gene Med; 2014; 16(1-2):40-53. PubMed ID: 24464652
[TBL] [Abstract][Full Text] [Related]
18. Herpes simplex virus/Sleeping Beauty vector-based embryonic gene transfer using the HSB5 mutant: loss of apparent transposition hyperactivity in vivo.
de Silva S; Mastrangelo MA; Lotta LT; Burris CA; Izsvák Z; Ivics Z; Bowers WJ
Hum Gene Ther; 2010 Nov; 21(11):1603-13. PubMed ID: 20507234
[TBL] [Abstract][Full Text] [Related]
19. Transposon vectors for gene-trap insertional mutagenesis in vertebrates.
Clark KJ; Geurts AM; Bell JB; Hackett PB
Genesis; 2004 Aug; 39(4):225-33. PubMed ID: 15286994
[TBL] [Abstract][Full Text] [Related]
20. Genotoxicity of retroviral hematopoietic stem cell gene therapy.
Trobridge GD
Expert Opin Biol Ther; 2011 May; 11(5):581-93. PubMed ID: 21375467
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]