These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 23216091)

  • 1. Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.
    Fang J; Uchiumi T; Yagi M; Matsumoto S; Amamoto R; Takazaki S; Yamaza H; Nonaka K; Kang D
    Biosci Rep; 2013 Feb; 33(2):e00021. PubMed ID: 23216091
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients.
    Fang J; Uchiumi T; Yagi M; Matsumoto S; Amamoto R; Saito T; Takazaki S; Kanki T; Yamaza H; Nonaka K; Kang D
    Biosci Rep; 2012 Dec; 32(6):631-9. PubMed ID: 22967083
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Miller (Genee-Wiedemann) syndrome represents a clinically and biochemically distinct subgroup of postaxial acrofacial dysostosis associated with partial deficiency of DHODH.
    Rainger J; Bengani H; Campbell L; Anderson E; Sokhi K; Lam W; Riess A; Ansari M; Smithson S; Lees M; Mercer C; McKenzie K; Lengfeld T; Gener Querol B; Branney P; McKay S; Morrison H; Medina B; Robertson M; Kohlhase J; Gordon C; Kirk J; Wieczorek D; Fitzpatrick DR
    Hum Mol Genet; 2012 Sep; 21(18):3969-83. PubMed ID: 22692683
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevated plasma dihydroorotate in Miller syndrome: Biochemical, diagnostic and clinical implications, and treatment with uridine.
    Duley JA; Henman MG; Carpenter KH; Bamshad MJ; Marshall GA; Ooi CY; Wilcken B; Pinner JR
    Mol Genet Metab; 2016 Sep; 119(1-2):83-90. PubMed ID: 27370710
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dihydroorotate dehydrogenase depletion hampers mitochondrial function and osteogenic differentiation in osteoblasts.
    Fang J; Yamaza H; Uchiumi T; Hoshino Y; Masuda K; Hirofuji Y; Wagener FA; Kang D; Nonaka K
    Eur J Oral Sci; 2016 Jun; 124(3):241-5. PubMed ID: 27086500
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Miller syndrome with novel dihydroorotate dehydrogenase gene mutations.
    Kinoshita F; Kondoh T; Komori K; Matsui T; Harada N; Yanai A; Fukuda M; Morifuji K; Matsumoto T
    Pediatr Int; 2011 Aug; 53(4):587-91. PubMed ID: 21851494
    [No Abstract]   [Full Text] [Related]  

  • 7. Mitochondrial ubiquinol oxidation is necessary for tumour growth.
    Martínez-Reyes I; Cardona LR; Kong H; Vasan K; McElroy GS; Werner M; Kihshen H; Reczek CR; Weinberg SE; Gao P; Steinert EM; Piseaux R; Budinger GRS; Chandel NS
    Nature; 2020 Sep; 585(7824):288-292. PubMed ID: 32641834
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dihydroorotate dehydrogenase in oxidative phosphorylation and cancer.
    Boukalova S; Hubackova S; Milosevic M; Ezrova Z; Neuzil J; Rohlena J
    Biochim Biophys Acta Mol Basis Dis; 2020 Jun; 1866(6):165759. PubMed ID: 32151633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dihydroorotat-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides.
    Löffler M; Jöckel J; Schuster G; Becker C
    Mol Cell Biochem; 1997 Sep; 174(1-2):125-9. PubMed ID: 9309676
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Facial dysostoses: Etiology, pathogenesis and management.
    Trainor PA; Andrews BT
    Am J Med Genet C Semin Med Genet; 2013 Nov; 163C(4):283-94. PubMed ID: 24123981
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome.
    Orozco Rodriguez JM; Wacklin-Knecht H; Knecht W
    Nucleosides Nucleotides Nucleic Acids; 2022; 41(12):1337-1358. PubMed ID: 35184687
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome.
    Orozco Rodriguez JM; Krupinska E; Wacklin-Knecht H; Knecht W
    Nucleosides Nucleotides Nucleic Acids; 2022; 41(12):1318-1336. PubMed ID: 35094635
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Familial postaxial acrofacial dysostosis syndrome.
    Giannotti A; Digilio MC; Virgili Q; Obregon MG; Guadagni AM; Ventura T; Dallapiccola B
    J Med Genet; 1992 Oct; 29(10):752. PubMed ID: 1433242
    [No Abstract]   [Full Text] [Related]  

  • 14. The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.
    Khutornenko AA; Dalina AA; Chernyak BV; Chumakov PM; Evstafieva AG
    Acta Naturae; 2014 Jan; 6(1):69-75. PubMed ID: 24772329
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
    Lafita-Navarro MC; Venkateswaran N; Kilgore JA; Kanji S; Han J; Barnes S; Williams NS; Buszczak M; Burma S; Conacci-Sorrell M
    PLoS Genet; 2020 Nov; 16(11):e1009117. PubMed ID: 33201894
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial nucleic acid binding proteins associated with diseases.
    Uchiumi T; Kang D
    Front Biosci (Landmark Ed); 2017 Jan; 22(1):168-179. PubMed ID: 27814609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Extra phenotypic features in a girl with Miller syndrome.
    Al Kaissi A; Roetzer KM; Ulz P; Heitzer E; Klaushofer K; Grill F
    Clin Dysmorphol; 2011 Apr; 20(2):66-72. PubMed ID: 21346561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of the mitochondrial pyrimidine biosynthesis enzyme dihydroorotate dehydrogenase by doxorubicin and brequinar sensitizes cancer cells to TRAIL-induced apoptosis.
    He T; Haapa-Paananen S; Kaminskyy VO; Kohonen P; Fey V; Zhivotovsky B; Kallioniemi O; Perälä M
    Oncogene; 2014 Jul; 33(27):3538-49. PubMed ID: 24013224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
    Bajzikova M; Kovarova J; Coelho AR; Boukalova S; Oh S; Rohlenova K; Svec D; Hubackova S; Endaya B; Judasova K; Bezawork-Geleta A; Kluckova K; Chatre L; Zobalova R; Novakova A; Vanova K; Ezrova Z; Maghzal GJ; Magalhaes Novais S; Olsinova M; Krobova L; An YJ; Davidova E; Nahacka Z; Sobol M; Cunha-Oliveira T; Sandoval-Acuña C; Strnad H; Zhang T; Huynh T; Serafim TL; Hozak P; Sardao VA; Koopman WJH; Ricchetti M; Oliveira PJ; Kolar F; Kubista M; Truksa J; Dvorakova-Hortova K; Pacak K; Gurlich R; Stocker R; Zhou Y; Berridge MV; Park S; Dong L; Rohlena J; Neuzil J
    Cell Metab; 2019 Feb; 29(2):399-416.e10. PubMed ID: 30449682
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyrimidine Pathway-Dependent and -Independent Functions of the Toxoplasma gondii Mitochondrial Dihydroorotate Dehydrogenase.
    Hortua Triana MA; Cajiao Herrera D; Zimmermann BH; Fox BA; Bzik DJ
    Infect Immun; 2016 Oct; 84(10):2974-81. PubMed ID: 27481247
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.