149 related articles for article (PubMed ID: 23218604)
1. Synthesis and evaluation of novel ligands for the histamine H₄ receptor based on a pyrrolo[2,3-d]pyrimidine scaffold.
Gao LJ; Schwed JS; Weizel L; De Jonghe S; Stark H; Herdewijn P
Bioorg Med Chem Lett; 2013 Jan; 23(1):132-7. PubMed ID: 23218604
[TBL] [Abstract][Full Text] [Related]
2. 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.
Sander K; Kottke T; Tanrikulu Y; Proschak E; Weizel L; Schneider EH; Seifert R; Schneider G; Stark H
Bioorg Med Chem; 2009 Oct; 17(20):7186-96. PubMed ID: 19773175
[TBL] [Abstract][Full Text] [Related]
3. New lead elements for histamine H
Espinosa-Bustos C; Frank A; Arancibia-Opazo S; Salas CO; Fierro A; Stark H
Bioorg Med Chem Lett; 2018 Sep; 28(17):2890-2893. PubMed ID: 30025902
[TBL] [Abstract][Full Text] [Related]
4. Combining quantum mechanical ligand conformation analysis and protein modeling to elucidate GPCR-ligand binding modes.
Schultes S; Engelhardt H; Roumen L; Zuiderveld OP; Haaksma EE; de Esch IJ; Leurs R; de Graaf C
ChemMedChem; 2013 Jan; 8(1):49-53. PubMed ID: 23161844
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.
Patanè E; Pittalà V; Guerrera F; Salerno L; Romeo G; Siracusa MA; Russo F; Manetti F; Botta M; Mereghetti I; Cagnotto A; Mennini T
J Med Chem; 2005 Apr; 48(7):2420-31. PubMed ID: 15801833
[TBL] [Abstract][Full Text] [Related]
6. Bispyrimidines as potent histamine H(4) receptor ligands: delineation of structure-activity relationships and detailed H(4) receptor binding mode.
Engelhardt H; Schultes S; de Graaf C; Nijmeijer S; Vischer HF; Zuiderveld OP; Dobler J; Stachurski K; Mayer M; Arnhof H; Scharn D; Haaksma EE; de Esch IJ; Leurs R
J Med Chem; 2013 Jun; 56(11):4264-76. PubMed ID: 23668417
[TBL] [Abstract][Full Text] [Related]
7. Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
Lee-Dutra A; Arienti KL; Buzard DJ; Hack MD; Khatuya H; Desai PJ; Nguyen S; Thurmond RL; Karlsson L; Edwards JP; Breitenbucher JG
Bioorg Med Chem Lett; 2006 Dec; 16(23):6043-8. PubMed ID: 16990005
[TBL] [Abstract][Full Text] [Related]
8. Structural requirements for inverse agonism and neutral antagonism of indole-, benzimidazole-, and thienopyrrole-derived histamine H4 receptor ligands.
Schneider EH; Strasser A; Thurmond RL; Seifert R
J Pharmacol Exp Ther; 2010 Aug; 334(2):513-21. PubMed ID: 20484153
[TBL] [Abstract][Full Text] [Related]
9. Identification and synthesis of substituted pyrrolo[2,3-d]pyrimidines as novel firefly luciferase inhibitors.
Liu Y; Fang J; Cai H; Xiao F; Ding K; Hu Y
Bioorg Med Chem; 2012 Sep; 20(18):5473-82. PubMed ID: 22898255
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and anti-HIV-1 activity of 4-substituted-7-(2'-deoxy-2'-fluoro-4'-azido-β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine analogues.
Guo X; Li Y; Tao L; Wang Q; Wang S; Hu W; Pan Z; Yang Q; Cui Y; Ge Z; Dong L; Yu X; An H; Song C; Chang J
Bioorg Med Chem Lett; 2011 Nov; 21(22):6770-2. PubMed ID: 21974951
[TBL] [Abstract][Full Text] [Related]
11. Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.
Müller CE; Geis U; Grahner B; Lanzner W; Eger K
J Med Chem; 1996 Jun; 39(13):2482-91. PubMed ID: 8691445
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and activity of novel 5-substituted pyrrolo[2,3-d]pyrimidine analogues as pp60(c-Src) tyrosine kinase inhibitors.
Olgen S; Isgör YG; Coban T
Arch Pharm (Weinheim); 2008 Feb; 341(2):113-20. PubMed ID: 18214841
[TBL] [Abstract][Full Text] [Related]
13. Tritium-labeled N(1)-[3-(1H-imidazol-4-yl)propyl]-N(2)-propionylguanidine ([(3)H]UR-PI294), a high-affinity histamine H(3) and H(4) receptor radioligand.
Igel P; Schnell D; Bernhardt G; Seifert R; Buschauer A
ChemMedChem; 2009 Feb; 4(2):225-31. PubMed ID: 19101971
[TBL] [Abstract][Full Text] [Related]
14. Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.
Kiss R; Kiss B; Könczöl A; Szalai F; Jelinek I; László V; Noszál B; Falus A; Keseru GM
J Med Chem; 2008 Jun; 51(11):3145-53. PubMed ID: 18459760
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.
Jung MH; Kim H; Choi WK; El-Gamal MI; Park JH; Yoo KH; Sim TB; Lee SH; Baek D; Hah JM; Cho JH; Oh CH
Bioorg Med Chem Lett; 2009 Dec; 19(23):6538-43. PubMed ID: 19857963
[TBL] [Abstract][Full Text] [Related]
16. High-resolution metabolic profiling towards G protein-coupled receptors: rapid and comprehensive screening of histamine H₄ receptor ligands.
Kool J; Rudebeck AF; Fleurbaaij F; Nijmeijer S; Falck D; Smits RA; Vischer HF; Leurs R; Niessen WM
J Chromatogr A; 2012 Oct; 1259():213-20. PubMed ID: 22520160
[TBL] [Abstract][Full Text] [Related]
17. Molecular determinants of ligand binding modes in the histamine H(4) receptor: linking ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) models to in silico guided receptor mutagenesis studies.
Istyastono EP; Nijmeijer S; Lim HD; van de Stolpe A; Roumen L; Kooistra AJ; Vischer HF; de Esch IJ; Leurs R; de Graaf C
J Med Chem; 2011 Dec; 54(23):8136-47. PubMed ID: 22003888
[TBL] [Abstract][Full Text] [Related]
18. Receptor-specific functional efficacies of alkyl imidazoles as dual histamine H3/H4 receptor ligands.
Kottke T; Sander K; Weizel L; Schneider EH; Seifert R; Stark H
Eur J Pharmacol; 2011 Mar; 654(3):200-8. PubMed ID: 21237145
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376.
Geyer R; Buschauer A
Arch Pharm (Weinheim); 2011 Dec; 344(12):775-85. PubMed ID: 21987304
[TBL] [Abstract][Full Text] [Related]
20. In silico characterization of ligand binding modes in the human histamine H4 receptor and their impact on receptor activation.
Werner T; Sander K; Tanrikulu Y; Kottke T; Proschak E; Stark H; Schneider G
Chembiochem; 2010 Sep; 11(13):1850-5. PubMed ID: 20665769
[No Abstract] [Full Text] [Related]
[Next] [New Search]
