BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 23220644)

  • 1. Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase.
    Meng H; Liu Y; Zhai Y; Lai L
    Eur J Med Chem; 2013 Jan; 59():160-7. PubMed ID: 23220644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.
    Sandanayaka V; Mamat B; Bhagat N; Bedell L; Halldorsdottir G; Sigthorsdottir H; Andrésson T; Kiselyov A; Gurney M; Singh J
    Bioorg Med Chem Lett; 2010 May; 20(9):2851-4. PubMed ID: 20371179
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thermodynamic properties of leukotriene A
    Wittmann SK; Kalinowsky L; Kramer JS; Bloecher R; Knapp S; Steinhilber D; Pogoryelov D; Proschak E; Heering J
    Bioorg Med Chem; 2016 Nov; 24(21):5243-5248. PubMed ID: 27651294
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A₂ inhibitors.
    Wu Y; Chen Z; Liu Y; Yu L; Zhou L; Yang S; Lai L
    Bioorg Med Chem; 2011 Jun; 19(11):3361-6. PubMed ID: 21555224
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hybrid Receptor-Bound/MM-GBSA-Per-residue Energy-Based Pharmacophore Modelling: Enhanced Approach for Identification of Selective LTA4H Inhibitors as Potential Anti-inflammatory Drugs.
    Appiah-Kubi P; Soliman M
    Cell Biochem Biophys; 2017 Mar; 75(1):35-48. PubMed ID: 27914004
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of dual target inhibitors against cyclooxygenases and leukotriene A4 hydrolyase.
    Chen Z; Wu Y; Liu Y; Yang S; Chen Y; Lai L
    J Med Chem; 2011 May; 54(10):3650-60. PubMed ID: 21542630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.
    Kirkland TA; Adler M; Bauman JG; Chen M; Haeggström JZ; King B; Kochanny MJ; Liang AM; Mendoza L; Phillips GB; Thunnissen M; Trinh L; Whitlow M; Ye B; Ye H; Parkinson J; Guilford WJ
    Bioorg Med Chem; 2008 May; 16(9):4963-83. PubMed ID: 18394906
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors.
    Calışkan B; Banoglu E
    Expert Opin Drug Discov; 2013 Jan; 8(1):49-63. PubMed ID: 23095029
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of benzofuran central cores for the inhibition of leukotriene A(4) hydrolase.
    Eccles W; Blevitt JM; Booker JN; Chrovian CC; Crawford S; de Leon AR; Deng X; Fourie AM; Grice CA; Herman K; Karlsson L; Kearney AM; Lee-Dutra A; Liang J; Luna R; Pippel D; Rao N; Riley JP; Santillán A; Savall B; Tanis VM; Xue X; Young AL
    Bioorg Med Chem Lett; 2013 Feb; 23(3):811-5. PubMed ID: 23260350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Azabenzthiazole inhibitors of leukotriene A₄ hydrolase.
    Tanis VM; Bacani GM; Blevitt JM; Chrovian CC; Crawford S; De Leon A; Fourie AM; Gomez L; Grice CA; Herman K; Kearney AM; Landry-Bayle AM; Lee-Dutra A; Nelson J; Riley JP; Santillán A; Wiener JJ; Xue X; Young AL
    Bioorg Med Chem Lett; 2012 Dec; 22(24):7504-11. PubMed ID: 23127888
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching.
    Wei D; Jiang X; Zhou L; Chen J; Chen Z; He C; Yang K; Liu Y; Pei J; Lai L
    J Med Chem; 2008 Dec; 51(24):7882-8. PubMed ID: 19090779
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pharmacophore-based virtual screening and Bayesian model for the identification of potential human leukotriene A4 hydrolase inhibitors.
    Thangapandian S; John S; Sakkiah S; Lee KW
    Eur J Med Chem; 2011 May; 46(5):1593-603. PubMed ID: 21377770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, docking, cytotoxicity, and LTA
    El-Naggar MH; Mira A; Abdel Bar FM; Shimizu K; Amer MM; Badria FA
    Bioorg Med Chem; 2017 Feb; 25(3):1277-1285. PubMed ID: 28065501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual anti-inflammatory and selective inhibition mechanism of leukotriene A4 hydrolase/aminopeptidase: insights from comparative molecular dynamics and binding free energy analyses.
    Appiah-Kubi P; Soliman ME
    J Biomol Struct Dyn; 2016 Nov; 34(11):2418-33. PubMed ID: 26555301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Feasibility and physiological relevance of designing highly potent aminopeptidase-sparing leukotriene A4 hydrolase inhibitors.
    Numao S; Hasler F; Laguerre C; Srinivas H; Wack N; Jäger P; Schmid A; Osmont A; Röthlisberger P; Houguenade J; Bergsdorf C; Dawson J; Carte N; Hofmann A; Markert C; Hardaker L; Billich A; Wolf RM; Penno CA; Bollbuck B; Miltz W; Röhn TA
    Sci Rep; 2017 Oct; 7(1):13591. PubMed ID: 29051536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological characterization of SC-57461A (3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid HCl), a potent and selective inhibitor of leukotriene A(4) hydrolase II: in vivo studies.
    Kachur JF; Askonas LJ; Villani-Price D; Ghoreishi-Haack N; Won-Kim S; Liang CD; Russell MA; Smith WG
    J Pharmacol Exp Ther; 2002 Feb; 300(2):583-7. PubMed ID: 11805220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of N-mercaptoacylcysteine derivatives as leukotriene A4 hydrolase inhibitors.
    Enomoto H; Morikawa Y; Miyake Y; Tsuji F; Mizuchi M; Suhara H; Fujimura K; Horiuchi M; Ban M
    Bioorg Med Chem Lett; 2009 Jan; 19(2):442-6. PubMed ID: 19042128
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyrrolidine and piperidine analogues of SC-57461A as potent, orally active inhibitors of leukotriene A(4) hydrolase.
    Penning TD; Chandrakumar NS; Desai BN; Djuric SW; Gasiecki AF; Liang CD; Miyashiro JM; Russell MA; Askonas LJ; Gierse JK; Harding EI; Highkin MK; Kachur JF; Kim SH; Villani-Price D; Pyla EY; Ghoreishi-Haack NS; Smith WG
    Bioorg Med Chem Lett; 2002 Dec; 12(23):3383-6. PubMed ID: 12419366
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of N-mercaptoacylproline and N-mercaptoacylthiazolidine-4-carboxylic acid derivatives as leukotriene A4 hydrolase inhibitors.
    Enomoto H; Morikawa Y; Miyake Y; Tsuji F; Mizuchi M; Suhara H; Fujimura K; Horiuchi M; Ban M
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4529-32. PubMed ID: 18674901
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular docking and pharmacophore filtering in the discovery of dual-inhibitors for human leukotriene A4 hydrolase and leukotriene C4 synthase.
    Thangapandian S; John S; Sakkiah S; Lee KW
    J Chem Inf Model; 2011 Jan; 51(1):33-44. PubMed ID: 21133343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.