123 related articles for article (PubMed ID: 23221771)
1. Intracellular NAD(+) depletion induces autophagic death in multiple myeloma cells.
Cea M; Cagnetta A; Patrone F; Nencioni A; Gobbi M; Anderson KC
Autophagy; 2013 Mar; 9(3):410-2. PubMed ID: 23221771
[TBL] [Abstract][Full Text] [Related]
2. Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition.
Cea M; Cagnetta A; Fulciniti M; Tai YT; Hideshima T; Chauhan D; Roccaro A; Sacco A; Calimeri T; Cottini F; Jakubikova J; Kong SY; Patrone F; Nencioni A; Gobbi M; Richardson P; Munshi N; Anderson KC
Blood; 2012 Oct; 120(17):3519-29. PubMed ID: 22955917
[TBL] [Abstract][Full Text] [Related]
3. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.
Hasmann M; Schemainda I
Cancer Res; 2003 Nov; 63(21):7436-42. PubMed ID: 14612543
[TBL] [Abstract][Full Text] [Related]
4. NAD depletion by FK866 induces autophagy.
Billington RA; Genazzani AA; Travelli C; Condorelli F
Autophagy; 2008 Apr; 4(3):385-7. PubMed ID: 18227641
[TBL] [Abstract][Full Text] [Related]
5. Nicotinamide phosphoribosyltransferase inhibitor APO866 induces C6 glioblastoma cell death via autophagy.
Yang P; Zhang L; Shi QJ; Lu YB; Wu M; Wei EQ; Zhang WP
Pharmazie; 2015 Oct; 70(10):650-5. PubMed ID: 26601421
[TBL] [Abstract][Full Text] [Related]
6. NAD metabolism fuels human and mouse intestinal inflammation.
Gerner RR; Klepsch V; Macheiner S; Arnhard K; Adolph TE; Grander C; Wieser V; Pfister A; Moser P; Hermann-Kleiter N; Baier G; Oberacher H; Tilg H; Moschen AR
Gut; 2018 Oct; 67(10):1813-1823. PubMed ID: 28877980
[TBL] [Abstract][Full Text] [Related]
7. Chemopotentiating effects of a novel NAD biosynthesis inhibitor, FK866, in combination with antineoplastic agents.
Pogrebniak A; Schemainda I; Azzam K; Pelka-Fleischer R; Nüssler V; Hasmann M
Eur J Med Res; 2006 Aug; 11(8):313-21. PubMed ID: 17052966
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of NAMPT markedly enhances plasma-activated medium-induced cell death in human breast cancer MDA-MB-231 cells.
Nagaya M; Hara H; Kamiya T; Adachi T
Arch Biochem Biophys; 2019 Nov; 676():108155. PubMed ID: 31628926
[TBL] [Abstract][Full Text] [Related]
9. FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells.
Schuster S; Penke M; Gorski T; Gebhardt R; Weiss TS; Kiess W; Garten A
Biochem Biophys Res Commun; 2015 Mar; 458(2):334-40. PubMed ID: 25656579
[TBL] [Abstract][Full Text] [Related]
10. Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE.
Bruzzone S; Fruscione F; Morando S; Ferrando T; Poggi A; Garuti A; D'Urso A; Selmo M; Benvenuto F; Cea M; Zoppoli G; Moran E; Soncini D; Ballestrero A; Sordat B; Patrone F; Mostoslavsky R; Uccelli A; Nencioni A
PLoS One; 2009 Nov; 4(11):e7897. PubMed ID: 19936064
[TBL] [Abstract][Full Text] [Related]
11. A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of human fibroblastic Hs68 cells via attenuation of NAD(+)-SIRT1 signaling.
Song TY; Yeh SL; Hu ML; Chen MY; Yang NC
Biogerontology; 2015 Dec; 16(6):789-800. PubMed ID: 26330291
[TBL] [Abstract][Full Text] [Related]
12. Nicotinamide phosphoribosyltransferase (NAMPT) activity is essential for survival of resting lymphocytes.
Pittelli M; Cavone L; Lapucci A; Oteri C; Felici R; Niccolai E; Amedei A; Chiarugi A
Immunol Cell Biol; 2014 Feb; 92(2):191-9. PubMed ID: 24275857
[TBL] [Abstract][Full Text] [Related]
13. Reciprocal potentiation of the antitumoral activities of FK866, an inhibitor of nicotinamide phosphoribosyltransferase, and etoposide or cisplatin in neuroblastoma cells.
Travelli C; Drago V; Maldi E; Kaludercic N; Galli U; Boldorini R; Di Lisa F; Tron GC; Canonico PL; Genazzani AA
J Pharmacol Exp Ther; 2011 Sep; 338(3):829-40. PubMed ID: 21685314
[TBL] [Abstract][Full Text] [Related]
14. The anti-lymphoma activity of APO866, an inhibitor of nicotinamide adenine dinucleotide biosynthesis, is potentialized when used in combination with anti-CD20 antibody.
Nahimana A; Aubry D; Breton CS; Majjigapu SR; Sordat B; Vogel P; Duchosal MA
Leuk Lymphoma; 2014 Sep; 55(9):2141-50. PubMed ID: 24283753
[TBL] [Abstract][Full Text] [Related]
15. ROS-Mediated 15-Hydroxyprostaglandin Dehydrogenase Degradation via Cysteine Oxidation Promotes NAD
Wang W; Hu Y; Wang X; Wang Q; Deng H
Cell Chem Biol; 2018 Mar; 25(3):255-261.e4. PubMed ID: 29307841
[TBL] [Abstract][Full Text] [Related]
16. Targeting the NAD Salvage Synthesis Pathway as a Novel Therapeutic Strategy for Osteosarcomas with Low NAPRT Expression.
Franceschini N; Oosting J; Tamsma M; Niessen B; Bruijn IB; van den Akker B; Kruisselbrink AB; Palubeckaitė I; Bovée JVMG; Cleton-Jansen AM
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34200964
[TBL] [Abstract][Full Text] [Related]
17. Targeting the NAD
Ye C; Qi L; Li X; Wang J; Yu J; Zhou B; Guo C; Chen J; Zheng S
Cell Commun Signal; 2020 Jan; 18(1):16. PubMed ID: 32005247
[TBL] [Abstract][Full Text] [Related]
18. On-target effect of FK866, a nicotinamide phosphoribosyl transferase inhibitor, by apoptosis-mediated death in chronic lymphocytic leukemia cells.
Gehrke I; Bouchard ED; Beiggi S; Poeppl AG; Johnston JB; Gibson SB; Banerji V
Clin Cancer Res; 2014 Sep; 20(18):4861-72. PubMed ID: 25172933
[TBL] [Abstract][Full Text] [Related]
19. EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells.
Mutz CN; Schwentner R; Aryee DNT; Bouchard EDJ; Mejia EM; Hatch GM; Kauer MO; Katschnig AM; Ban J; Garten A; Alonso J; Banerji V; Kovar H
Oncotarget; 2017 Apr; 8(15):24679-24693. PubMed ID: 28160567
[TBL] [Abstract][Full Text] [Related]
20. Autophagy and Myeloma.
Zheng Z; Wang L; Cheng S; Wang Y; Zhao W
Adv Exp Med Biol; 2020; 1207():625-631. PubMed ID: 32671780
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
