215 related articles for article (PubMed ID: 23221912)
1. Role of the activation gate in determining the extracellular potassium dependency of block of HERG by trapped drugs.
Pareja K; Chu E; Dodyk K; Richter K; Miller A
Channels (Austin); 2013 Jan; 7(1):23-33. PubMed ID: 23221912
[TBL] [Abstract][Full Text] [Related]
2. Extracellular potassium dependency of block of HERG by quinidine and cisapride is primarily determined by the permeant ion and not by inactivation.
Barrows B; Cheung K; Bialobrzeski T; Foster J; Schulze J; Miller A
Channels (Austin); 2009; 3(4):239-48. PubMed ID: 19617705
[TBL] [Abstract][Full Text] [Related]
3. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
Thomas D; Karle CA; Kiehn J
Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
[TBL] [Abstract][Full Text] [Related]
4. Molecular determinants of HERG channel block.
Kamiya K; Niwa R; Mitcheson JS; Sanguinetti MC
Mol Pharmacol; 2006 May; 69(5):1709-16. PubMed ID: 16474003
[TBL] [Abstract][Full Text] [Related]
5. Probing the interaction between inactivation gating and Dd-sotalol block of HERG.
Numaguchi H; Mullins FM; Johnson JP; Johns DC; Po SS; Yang IC; Tomaselli GF; Balser JR
Circ Res; 2000 Nov; 87(11):1012-8. PubMed ID: 11090546
[TBL] [Abstract][Full Text] [Related]
6. Predicting drug-hERG channel interactions that cause acquired long QT syndrome.
Sanguinetti MC; Mitcheson JS
Trends Pharmacol Sci; 2005 Mar; 26(3):119-24. PubMed ID: 15749156
[TBL] [Abstract][Full Text] [Related]
7. Molecular determinants of cocaine block of human ether-á-go-go-related gene potassium channels.
Guo J; Gang H; Zhang S
J Pharmacol Exp Ther; 2006 May; 317(2):865-74. PubMed ID: 16397089
[TBL] [Abstract][Full Text] [Related]
8. [HERG K+ channel, the target of anti-arrhythmias drugs].
Guan FY; Yang SJ
Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
[TBL] [Abstract][Full Text] [Related]
9. Molecular determinants of hERG channel block by terfenadine and cisapride.
Kamiya K; Niwa R; Morishima M; Honjo H; Sanguinetti MC
J Pharmacol Sci; 2008 Nov; 108(3):301-7. PubMed ID: 18987434
[TBL] [Abstract][Full Text] [Related]
10. Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels.
Limberis JT; Su Z; Cox BF; Gintant GA; Martin RL
Clin Exp Pharmacol Physiol; 2006 Nov; 33(11):1059-65. PubMed ID: 17042915
[TBL] [Abstract][Full Text] [Related]
11. The Susceptibilities of Human Ether-à-Go-Go-Related Gene Channel with the G487R Mutation to Arrhythmogenic Factors.
Hisajima N; Hata Y; Kinoshita K; Fukushima T; Nishida N; Kano M; Tabata T
Biol Pharm Bull; 2015; 38(5):781-4. PubMed ID: 25947924
[TBL] [Abstract][Full Text] [Related]
12. Modulation of HERG potassium channel function by drug action.
Thomas D; Karle CA; Kiehn J
Ann Med; 2004; 36 Suppl 1():41-6. PubMed ID: 15176423
[TBL] [Abstract][Full Text] [Related]
13. Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines.
Guo J; Massaeli H; Xu J; Jia Z; Wigle JT; Mesaeli N; Zhang S
J Clin Invest; 2009 Sep; 119(9):2745-57. PubMed ID: 19726881
[TBL] [Abstract][Full Text] [Related]
14. An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome.
Gravel AE; Arnold AA; Dufourc EJ; Marcotte I
Biochim Biophys Acta; 2013 Jun; 1828(6):1494-502. PubMed ID: 23473737
[TBL] [Abstract][Full Text] [Related]
15. Stimulation of N-terminal truncated isoform of androgen receptor stabilizes human ether-á-go-go-related gene-encoded potassium channel protein via activation of extracellular signal regulated kinase 1/2.
Wu ZY; Chen K; Haendler B; McDonald TV; Bian JS
Endocrinology; 2008 Oct; 149(10):5061-9. PubMed ID: 18599551
[TBL] [Abstract][Full Text] [Related]
16. Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.
Rajamani S; Anderson CL; Anson BD; January CT
Circulation; 2002 Jun; 105(24):2830-5. PubMed ID: 12070109
[TBL] [Abstract][Full Text] [Related]
17. Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.
Dennis AT; Nassal D; Deschenes I; Thomas D; Ficker E
J Biol Chem; 2011 Sep; 286(39):34413-25. PubMed ID: 21832094
[TBL] [Abstract][Full Text] [Related]
18. Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656.
Park SJ; Kim KS; Kim EJ
J Appl Toxicol; 2008 Mar; 28(2):104-11. PubMed ID: 17516459
[TBL] [Abstract][Full Text] [Related]
19. hERG potassium channels and cardiac arrhythmia.
Sanguinetti MC; Tristani-Firouzi M
Nature; 2006 Mar; 440(7083):463-9. PubMed ID: 16554806
[TBL] [Abstract][Full Text] [Related]
20. Molecular mechanisms for drug interactions with hERG that cause long QT syndrome.
Stansfeld PJ; Sutcliffe MJ; Mitcheson JS
Expert Opin Drug Metab Toxicol; 2006 Feb; 2(1):81-94. PubMed ID: 16863470
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
