These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 23225006)

  • 21. Nucleation Inhibition of Huntingtin Protein (htt) by Polyproline PPII Helices: A Potential Interaction with the N-Terminal α-Helical Region of Htt.
    Arndt JR; Chaibva M; Beasley M; Kiani Karanji A; Ghassabi Kondalaji S; Khakinejad M; Sarver O; Legleiter J; Valentine SJ
    Biochemistry; 2020 Feb; 59(4):436-449. PubMed ID: 31814404
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain.
    Díaz-Hernández M; Moreno-Herrero F; Gómez-Ramos P; Morán MA; Ferrer I; Baró AM; Avila J; Hernández F; Lucas JJ
    J Neurosci; 2004 Oct; 24(42):9361-71. PubMed ID: 15496672
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Aggregation and fibril morphology of the Arctic mutation of Alzheimer's Aβ peptide by CD, TEM, STEM and in situ AFM.
    Norlin N; Hellberg M; Filippov A; Sousa AA; Gröbner G; Leapman RD; Almqvist N; Antzutkin ON
    J Struct Biol; 2012 Oct; 180(1):174-89. PubMed ID: 22750418
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Amyloid-like fibril formation by polyQ proteins: a critical balance between the polyQ length and the constraints imposed by the host protein.
    Scarafone N; Pain C; Fratamico A; Gaspard G; Yilmaz N; Filée P; Galleni M; Matagne A; Dumoulin M
    PLoS One; 2012; 7(3):e31253. PubMed ID: 22438863
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Conformational switch of polyglutamine-expanded huntingtin into benign aggregates leads to neuroprotective effect.
    Sun CS; Lee CC; Li YN; Yao-Chen Yang S; Lin CH; Chang YC; Liu PF; He RY; Wang CH; Chen W; Chern Y; Jen-Tse Huang J
    Sci Rep; 2015 Oct; 5():14992. PubMed ID: 26450664
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties.
    Mishra R; Hoop CL; Kodali R; Sahoo B; van der Wel PC; Wetzel R
    J Mol Biol; 2012 Nov; 424(1-2):1-14. PubMed ID: 22999956
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments.
    Jayaraman M; Kodali R; Sahoo B; Thakur AK; Mayasundari A; Mishra R; Peterson CB; Wetzel R
    J Mol Biol; 2012 Feb; 415(5):881-99. PubMed ID: 22178474
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The emerging role of the first 17 amino acids of huntingtin in Huntington's disease.
    Arndt JR; Chaibva M; Legleiter J
    Biomol Concepts; 2015 Mar; 6(1):33-46. PubMed ID: 25741791
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Huntingtin aggregation kinetics and their pathological role in a Drosophila Huntington's disease model.
    Weiss KR; Kimura Y; Lee WC; Littleton JT
    Genetics; 2012 Feb; 190(2):581-600. PubMed ID: 22095086
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Atomic force microscopy analysis of the Huntington protein nanofibril formation.
    Dahlgren PR; Karymov MA; Bankston J; Holden T; Thumfort P; Ingram VM; Lyubchenko YL
    Nanomedicine; 2005 Mar; 1(1):52-7. PubMed ID: 17292058
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates.
    Khurana R; Gillespie JR; Talapatra A; Minert LJ; Ionescu-Zanetti C; Millett I; Fink AL
    Biochemistry; 2001 Mar; 40(12):3525-35. PubMed ID: 11297418
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules.
    Sontag EM; Lotz GP; Yang G; Sontag CJ; Cummings BJ; Glabe CG; Muchowski PJ; Thompson LM
    J Huntingtons Dis; 2012; 1(1):119-32. PubMed ID: 24086178
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo.
    Scherzinger E; Lurz R; Turmaine M; Mangiarini L; Hollenbach B; Hasenbank R; Bates GP; Davies SW; Lehrach H; Wanker EE
    Cell; 1997 Aug; 90(3):549-58. PubMed ID: 9267034
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production.
    Hands S; Sajjad MU; Newton MJ; Wyttenbach A
    J Biol Chem; 2011 Dec; 286(52):44512-20. PubMed ID: 21984825
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Sedimentation Velocity Analysis of the Size Distribution of Amyloid Oligomers and Fibrils.
    Mok YF; Howlett GJ; Griffin MD
    Methods Enzymol; 2015; 562():241-56. PubMed ID: 26412655
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Implications of the Orb2 Amyloid Structure in Huntington's Disease.
    Hervás R; Murzin AG; Si K
    Int J Mol Sci; 2020 Sep; 21(18):. PubMed ID: 32967102
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Polyglutamine expansion mutation yields a pathological epitope linked to nucleation of protein aggregate: determinant of Huntington's disease onset.
    Sugaya K; Matsubara S; Kagamihara Y; Kawata A; Hayashi H
    PLoS One; 2007 Jul; 2(7):e635. PubMed ID: 17653262
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Properties of polyglutamine expansion in vitro and in a cellular model for Huntington's disease.
    Lunkes A; Trottier Y; Fagart J; Schultz P; Zeder-Lutz G; Moras D; Mandel JL
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1013-9. PubMed ID: 10434300
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Mechanisms of ataxin-3 misfolding and fibril formation: kinetic analysis of a disease-associated polyglutamine protein.
    Ellisdon AM; Pearce MC; Bottomley SP
    J Mol Biol; 2007 Apr; 368(2):595-605. PubMed ID: 17362987
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Polyglutamine induced misfolding of huntingtin exon1 is modulated by the flanking sequences.
    Lakhani VV; Ding F; Dokholyan NV
    PLoS Comput Biol; 2010 Apr; 6(4):e1000772. PubMed ID: 20442863
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.