BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 23226398)

  • 1. The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesis.
    Fan X; Liu X; Hao S; Wang B; Robinson ML; Monnier VM
    PLoS One; 2012; 7(11):e50832. PubMed ID: 23226398
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens.
    Fan X; Zhou S; Wang B; Hom G; Guo M; Li B; Yang J; Vaysburg D; Monnier VM
    Mol Cell Proteomics; 2015 Dec; 14(12):3211-23. PubMed ID: 26453637
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Age-related nuclear cataract-oxidation is the key.
    Truscott RJ
    Exp Eye Res; 2005 May; 80(5):709-25. PubMed ID: 15862178
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins.
    Whitson JA; Wilmarth PA; Klimek J; Monnier VM; David L; Fan X
    Free Radic Biol Med; 2017 Dec; 113():84-96. PubMed ID: 28951044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts.
    Pendergrass W; Zitnik G; Tsai R; Wolf N
    Mol Vis; 2010 Aug; 16():1496-513. PubMed ID: 20806081
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative proteomics analysis by iTRAQ in human nuclear cataracts of different ages and normal lens nuclei.
    Zhou HY; Yan H; Wang LL; Yan WJ; Shui YB; Beebe DC
    Proteomics Clin Appl; 2015 Aug; 9(7-8):776-86. PubMed ID: 25418515
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.
    Dalton TP; Dieter MZ; Yang Y; Shertzer HG; Nebert DW
    Biochem Biophys Res Commun; 2000 Dec; 279(2):324-9. PubMed ID: 11118286
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice.
    Reddy VN; Giblin FJ; Lin LR; Dang L; Unakar NJ; Musch DC; Boyle DL; Takemoto LJ; Ho YS; Knoernschild T; Juenemann A; Lütjen-Drecoll E
    Invest Ophthalmol Vis Sci; 2001 Dec; 42(13):3247-55. PubMed ID: 11726630
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis.
    Whitson JA; Sell DR; Goodman MC; Monnier VM; Fan X
    Invest Ophthalmol Vis Sci; 2016 Jul; 57(8):3914-25. PubMed ID: 27472077
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Does oxidative stress play any role in diabetic cataract formation? ----Re-evaluation using a thioltransferase gene knockout mouse model.
    Zhang J; Yan H; Lou MF
    Exp Eye Res; 2017 Aug; 161():36-42. PubMed ID: 28579033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Prevention of age-related truncation of γ-glutamylcysteine ligase catalytic subunit (GCLC) delays cataract formation.
    Wei Z; Hao C; Radeen KR; Srinivasagan R; Chen JK; Sharma S; McGee-Lawrence ME; Hamrick MW; Monnier VM; Fan X
    Sci Adv; 2024 Apr; 10(17):eadl1088. PubMed ID: 38669339
    [TBL] [Abstract][Full Text] [Related]  

  • 12. AlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice.
    Andley UP
    BMC Ophthalmol; 2009 Jul; 9():4. PubMed ID: 19619312
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Spatial distributions of glutathione and its endogenous conjugates in normal bovine lens and a model of lens aging.
    Nye-Wood MG; Spraggins JM; Caprioli RM; Schey KL; Donaldson PJ; Grey AC
    Exp Eye Res; 2017 Jan; 154():70-78. PubMed ID: 27838309
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nuclear light scattering, disulfide formation and membrane damage in lenses of older guinea pigs treated with hyperbaric oxygen.
    Giblin FJ; Padgaonkar VA; Leverenz VR; Lin LR; Lou MF; Unakar NJ; Dang L; Dickerson JE; Reddy VN
    Exp Eye Res; 1995 Mar; 60(3):219-35. PubMed ID: 7789403
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Age-related cataract progression in five mouse models for anti-oxidant protection or hormonal influence.
    Wolf N; Penn P; Pendergrass W; Van Remmen H; Bartke A; Rabinovitch P; Martin GM
    Exp Eye Res; 2005 Sep; 81(3):276-85. PubMed ID: 16129095
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of GSH in alphaA-expressing human lens epithelial cell lines and in alphaA knockout mouse lenses.
    Kannan R; Ouyang B; Wawrousek E; Kaplowitz N; Andley UP
    Invest Ophthalmol Vis Sci; 2001 Feb; 42(2):409-16. PubMed ID: 11157875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
    Wang B; Hom G; Zhou S; Guo M; Li B; Yang J; Monnier VM; Fan X
    Aging Cell; 2017 Apr; 16(2):244-261. PubMed ID: 28177569
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse.
    Graw J; Neuhäuser-Klaus A; Löster J; Favor J
    Invest Ophthalmol Vis Sci; 2002 Jan; 43(1):236-40. PubMed ID: 11773036
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of glutathione biosynthesis in endothelial dysfunction and fibrosis.
    Espinosa-Díez C; Miguel V; Vallejo S; Sánchez FJ; Sandoval E; Blanco E; Cannata P; Peiró C; Sánchez-Ferrer CF; Lamas S
    Redox Biol; 2018 Apr; 14():88-99. PubMed ID: 28888203
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reactive cysteine residues in the oxidative dimerization and Cu
    Ramkumar S; Fan X; Wang B; Yang S; Monnier VM
    Biochim Biophys Acta Mol Basis Dis; 2018 Nov; 1864(11):3595-3604. PubMed ID: 30251679
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.