BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

270 related articles for article (PubMed ID: 23235147)

  • 1. The IRE1α-XBP1 pathway positively regulates parathyroid hormone (PTH)/PTH-related peptide receptor expression and is involved in pth-induced osteoclastogenesis.
    Tohmonda T; Yoda M; Mizuochi H; Morioka H; Matsumoto M; Urano F; Toyama Y; Horiuchi K
    J Biol Chem; 2013 Jan; 288(3):1691-5. PubMed ID: 23235147
    [TBL] [Abstract][Full Text] [Related]  

  • 2. IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis.
    Tohmonda T; Yoda M; Iwawaki T; Matsumoto M; Nakamura M; Mikoshiba K; Toyama Y; Horiuchi K
    J Clin Invest; 2015 Aug; 125(8):3269-79. PubMed ID: 26193638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma.
    Mimura N; Fulciniti M; Gorgun G; Tai YT; Cirstea D; Santo L; Hu Y; Fabre C; Minami J; Ohguchi H; Kiziltepe T; Ikeda H; Kawano Y; French M; Blumenthal M; Tam V; Kertesz NL; Malyankar UM; Hokenson M; Pham T; Zeng Q; Patterson JB; Richardson PG; Munshi NC; Anderson KC
    Blood; 2012 Jun; 119(24):5772-81. PubMed ID: 22538852
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IRE1α dissociates with BiP and inhibits ER stress-mediated apoptosis in cartilage development.
    Han X; Zhou J; Zhang P; Song F; Jiang R; Li M; Xia F; Guo FJ
    Cell Signal; 2013 Nov; 25(11):2136-46. PubMed ID: 23816533
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TGF-beta type II receptor phosphorylates PTH receptor to integrate bone remodelling signalling.
    Qiu T; Wu X; Zhang F; Clemens TL; Wan M; Cao X
    Nat Cell Biol; 2010 Mar; 12(3):224-34. PubMed ID: 20139972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.
    Wang FM; Galson DL; Roodman GD; Ouyang H
    Exp Hematol; 2011 Oct; 39(10):999-1006. PubMed ID: 21723843
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix.
    Tohmonda T; Miyauchi Y; Ghosh R; Yoda M; Uchikawa S; Takito J; Morioka H; Nakamura M; Iwawaki T; Chiba K; Toyama Y; Urano F; Horiuchi K
    EMBO Rep; 2011 May; 12(5):451-7. PubMed ID: 21415858
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage.
    Guo FJ; Xiong Z; Lu X; Ye M; Han X; Jiang R
    Cell Signal; 2014 Feb; 26(2):332-42. PubMed ID: 24269637
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in
    Zundell JA; Fukumoto T; Lin J; Fatkhudinov N; Nacarelli T; Kossenkov AV; Liu Q; Cassel J; Hu CA; Wu S; Zhang R
    Cancer Res; 2021 Oct; 81(20):5325-5335. PubMed ID: 34548333
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins.
    Oikawa D; Iwawaki T
    Biochem Biophys Res Commun; 2013 Apr; 433(4):426-31. PubMed ID: 23541586
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.
    Namba T; Chu K; Kodama R; Byun S; Yoon KW; Hiraki M; Mandinova A; Lee SW
    Oncotarget; 2015 Aug; 6(24):19990-20001. PubMed ID: 26254280
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Constitutive role for IRE1α-XBP1 signaling pathway in the insulin-mediated hepatic lipogenic program.
    Ning J; Hong T; Ward A; Pi J; Liu Z; Liu HY; Cao W
    Endocrinology; 2011 Jun; 152(6):2247-55. PubMed ID: 21447637
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis.
    Jiang S; Yan C; Fang QC; Shao ML; Zhang YL; Liu Y; Deng YP; Shan B; Liu JQ; Li HT; Yang L; Zhou J; Dai Z; Liu Y; Jia WP
    J Biol Chem; 2014 Oct; 289(43):29751-65. PubMed ID: 25170079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response.
    Lee K; Tirasophon W; Shen X; Michalak M; Prywes R; Okada T; Yoshida H; Mori K; Kaufman RJ
    Genes Dev; 2002 Feb; 16(4):452-66. PubMed ID: 11850408
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The molecular mechanisms of XBP-1 gene silencing on IRE1α-TRAF2-ASK1-JNK pathways in oral squamous cell carcinoma under endoplasmic reticulum stress.
    Chen H; Yang H; Pan L; Wang W; Liu X; Ren X; Liu Y; Liu W; Zhang Y; Jiang L; Li K; Zhang B; Wang LX
    Biomed Pharmacother; 2016 Feb; 77():108-13. PubMed ID: 26796273
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling.
    Yu B; Zhao X; Yang C; Crane J; Xian L; Lu W; Wan M; Cao X
    J Bone Miner Res; 2012 Sep; 27(9):2001-14. PubMed ID: 22589223
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PTH1 receptor is involved in mediating cellular response to long-chain polyunsaturated fatty acids.
    Candelario J; Tavakoli H; Chachisvilis M
    PLoS One; 2012; 7(12):e52583. PubMed ID: 23300710
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis.
    Sha H; He Y; Chen H; Wang C; Zenno A; Shi H; Yang X; Zhang X; Qi L
    Cell Metab; 2009 Jun; 9(6):556-64. PubMed ID: 19490910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.
    Kharabi Masouleh B; Geng H; Hurtz C; Chan LN; Logan AC; Chang MS; Huang C; Swaminathan S; Sun H; Paietta E; Melnick AM; Koeffler P; Müschen M
    Proc Natl Acad Sci U S A; 2014 May; 111(21):E2219-28. PubMed ID: 24821775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1.
    Ming J; Ruan S; Wang M; Ye D; Fan N; Meng Q; Tian B; Huang T
    Oncotarget; 2015 Dec; 6(38):40692-703. PubMed ID: 26517687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.