These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Arsenic trioxide reactivates proteasome-dependent degradation of mutant p53 protein in cancer cells in part via enhanced expression of Pirh2 E3 ligase. Yan W; Jung YS; Zhang Y; Chen X PLoS One; 2014; 9(8):e103497. PubMed ID: 25116336 [TBL] [Abstract][Full Text] [Related]
4. Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein. Yan W; Chen X; Zhang Y; Zhang J; Jung YS; Chen X J Biol Chem; 2013 Feb; 288(5):2907-13. PubMed ID: 23271742 [TBL] [Abstract][Full Text] [Related]
5. The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation. Jung YS; Qian Y; Chen X J Biol Chem; 2011 Oct; 286(41):35388-35395. PubMed ID: 21852228 [TBL] [Abstract][Full Text] [Related]
6. Pirh2 E3 ubiquitin ligase targets DNA polymerase eta for 20S proteasomal degradation. Jung YS; Liu G; Chen X Mol Cell Biol; 2010 Feb; 30(4):1041-8. PubMed ID: 20008555 [TBL] [Abstract][Full Text] [Related]
7. PLAGL2 controls the stability of Pirh2, an E3 ubiquitin ligase for p53. Zheng G; Ning J; Yang YC Biochem Biophys Res Commun; 2007 Dec; 364(2):344-50. PubMed ID: 17950244 [TBL] [Abstract][Full Text] [Related]
8. Itch/AIP4 associates with and promotes p63 protein degradation. Rossi M; De Simone M; Pollice A; Santoro R; La Mantia G; Guerrini L; Calabrò V Cell Cycle; 2006 Aug; 5(16):1816-22. PubMed ID: 16861923 [TBL] [Abstract][Full Text] [Related]
9. Pirh2: an E3 ligase with central roles in the regulation of cell cycle, DNA damage response, and differentiation. Halaby MJ; Hakem R; Hakem A Cell Cycle; 2013 Sep; 12(17):2733-7. PubMed ID: 23966173 [TBL] [Abstract][Full Text] [Related]
10. SCYL1 binding protein 1 promotes the ubiquitin-dependent degradation of Pirh2 and has tumor-suppressive function in the development of hepatocellular carcinoma. Hu L; Liu M; Chen L; Chan TH; Wang J; Huo KK; Zheng BJ; Xie D; Guan XY Carcinogenesis; 2012 Aug; 33(8):1581-8. PubMed ID: 22570270 [TBL] [Abstract][Full Text] [Related]
11. The Regulation of Tumor Suppressor p63 by the Ubiquitin-Proteasome System. Armstrong SR; Wu H; Wang B; Abuetabh Y; Sergi C; Leng RP Int J Mol Sci; 2016 Dec; 17(12):. PubMed ID: 27929429 [TBL] [Abstract][Full Text] [Related]
12. The E3 ubiquitin ligase Itch controls the protein stability of p63. Rossi M; Aqeilan RI; Neale M; Candi E; Salomoni P; Knight RA; Croce CM; Melino G Proc Natl Acad Sci U S A; 2006 Aug; 103(34):12753-8. PubMed ID: 16908849 [TBL] [Abstract][Full Text] [Related]
13. WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis. Li Y; Zhou Z; Chen C Cell Death Differ; 2008 Dec; 15(12):1941-51. PubMed ID: 18806757 [TBL] [Abstract][Full Text] [Related]
14. Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation. Di Costanzo A; Festa L; Duverger O; Vivo M; Guerrini L; La Mantia G; Morasso MI; Calabrò V Cell Cycle; 2009 Apr; 8(8):1185-95. PubMed ID: 19282665 [TBL] [Abstract][Full Text] [Related]
15. Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1. Hattori T; Isobe T; Abe K; Kikuchi H; Kitagawa K; Oda T; Uchida C; Kitagawa M Cancer Res; 2007 Nov; 67(22):10789-95. PubMed ID: 18006823 [TBL] [Abstract][Full Text] [Related]
16. Pirh2, a ubiquitin E3 ligase, inhibits p73 transcriptional activity by promoting its ubiquitination. Wu H; Zeinab RA; Flores ER; Leng RP Mol Cancer Res; 2011 Dec; 9(12):1780-90. PubMed ID: 21994467 [TBL] [Abstract][Full Text] [Related]
17. Pirh2, an E3 ligase, regulates the AIP4-p73 regulatory pathway by modulating AIP4 expression and ubiquitination. Abou Zeinab R; Wu HH; Abuetabh Y; Leng S; Sergi C; Eisenstat DD; Leng RP Carcinogenesis; 2021 Apr; 42(4):650-662. PubMed ID: 33569599 [TBL] [Abstract][Full Text] [Related]
18. The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1. Bergiers I; Bridoux L; Nguyen N; Twizere JC; Rezsöhazy R PLoS One; 2013; 8(11):e80387. PubMed ID: 24244684 [TBL] [Abstract][Full Text] [Related]
19. Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains. Corcoran CA; Montalbano J; Sun H; He Q; Huang Y; Sheikh MS J Biol Chem; 2009 Aug; 284(33):21955-21970. PubMed ID: 19483087 [TBL] [Abstract][Full Text] [Related]
20. Functional interplay between p63 and p53 controls RUNX1 function in the transition from proliferation to differentiation in human keratinocytes. Masse I; Barbollat-Boutrand L; Molina M; Berthier-Vergnes O; Joly-Tonetti N; Martin MT; Caron de Fromentel C; Kanitakis J; Lamartine J Cell Death Dis; 2012 Jun; 3(6):e318. PubMed ID: 22673192 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]