BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

266 related articles for article (PubMed ID: 23241025)

  • 1. Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.
    Rannikko EH; Vesterager LB; Shaik JH; Weber SS; Cornejo Castro EM; Fog K; Jensen PH; Kahle PJ
    J Neurochem; 2013 Apr; 125(2):314-27. PubMed ID: 23241025
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease.
    Hulleman JD; Mirzaei H; Guigard E; Taylor KL; Ray SS; Kay CM; Regnier FE; Rochet JC
    Biochemistry; 2007 May; 46(19):5776-89. PubMed ID: 17451229
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1.
    Waak J; Weber SS; Görner K; Schall C; Ichijo H; Stehle T; Kahle PJ
    J Biol Chem; 2009 May; 284(21):14245-57. PubMed ID: 19293155
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.
    Alvarez-Castelao B; Muñoz C; Sánchez I; Goethals M; Vandekerckhove J; Castaño JG
    Biochim Biophys Acta; 2012 Feb; 1823(2):524-33. PubMed ID: 22173095
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1.
    Görner K; Holtorf E; Waak J; Pham TT; Vogt-Weisenhorn DM; Wurst W; Haass C; Kahle PJ
    J Biol Chem; 2007 May; 282(18):13680-91. PubMed ID: 17331951
    [TBL] [Abstract][Full Text] [Related]  

  • 6. L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
    Miller DW; Ahmad R; Hague S; Baptista MJ; Canet-Aviles R; McLendon C; Carter DM; Zhu PP; Stadler J; Chandran J; Klinefelter GR; Blackstone C; Cookson MR
    J Biol Chem; 2003 Sep; 278(38):36588-95. PubMed ID: 12851414
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization.
    Blackinton J; Ahmad R; Miller DW; van der Brug MP; Canet-Avilés RM; Hague SM; Kaleem M; Cookson MR
    Brain Res Mol Brain Res; 2005 Mar; 134(1):76-83. PubMed ID: 15790532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mitochondrial LonP1 protease is implicated in the degradation of unstable Parkinson's disease-associated DJ-1/PARK 7 missense mutants.
    Sánchez-Lanzas R; Castaño JG
    Sci Rep; 2021 Apr; 11(1):7320. PubMed ID: 33795807
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.
    Xu J; Zhong N; Wang H; Elias JE; Kim CY; Woldman I; Pifl C; Gygi SP; Geula C; Yankner BA
    Hum Mol Genet; 2005 May; 14(9):1231-41. PubMed ID: 15790595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization.
    Moore DJ; Zhang L; Dawson TM; Dawson VL
    J Neurochem; 2003 Dec; 87(6):1558-67. PubMed ID: 14713311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular basis for the structural instability of human DJ-1 induced by the L166P mutation associated with Parkinson's disease.
    Anderson PC; Daggett V
    Biochemistry; 2008 Sep; 47(36):9380-93. PubMed ID: 18707128
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease.
    Neumann M; Müller V; Görner K; Kretzschmar HA; Haass C; Kahle PJ
    Acta Neuropathol; 2004 Jun; 107(6):489-96. PubMed ID: 14991385
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.
    Görner K; Holtorf E; Odoy S; Nuscher B; Yamamoto A; Regula JT; Beyer K; Haass C; Kahle PJ
    J Biol Chem; 2004 Feb; 279(8):6943-51. PubMed ID: 14607841
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients.
    Takahashi-Niki K; Niki T; Taira T; Iguchi-Ariga SM; Ariga H
    Biochem Biophys Res Commun; 2004 Jul; 320(2):389-97. PubMed ID: 15219840
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress.
    Moore DJ; Zhang L; Troncoso J; Lee MK; Hattori N; Mizuno Y; Dawson TM; Dawson VL
    Hum Mol Genet; 2005 Jan; 14(1):71-84. PubMed ID: 15525661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease.
    Zondler L; Miller-Fleming L; Repici M; Gonçalves S; Tenreiro S; Rosado-Ramos R; Betzer C; Straatman KR; Jensen PH; Giorgini F; Outeiro TF
    Cell Death Dis; 2014 Jul; 5(7):e1350. PubMed ID: 25058424
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex.
    Im JY; Lee KW; Junn E; Mouradian MM
    Neurosci Res; 2010 Jul; 67(3):203-8. PubMed ID: 20385180
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death.
    Junn E; Taniguchi H; Jeong BS; Zhao X; Ichijo H; Mouradian MM
    Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9691-6. PubMed ID: 15983381
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
    Irrcher I; Aleyasin H; Seifert EL; Hewitt SJ; Chhabra S; Phillips M; Lutz AK; Rousseaux MW; Bevilacqua L; Jahani-Asl A; Callaghan S; MacLaurin JG; Winklhofer KF; Rizzu P; Rippstein P; Kim RH; Chen CX; Fon EA; Slack RS; Harper ME; McBride HM; Mak TW; Park DS
    Hum Mol Genet; 2010 Oct; 19(19):3734-46. PubMed ID: 20639397
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis.
    Zhang L; Shimoji M; Thomas B; Moore DJ; Yu SW; Marupudi NI; Torp R; Torgner IA; Ottersen OP; Dawson TM; Dawson VL
    Hum Mol Genet; 2005 Jul; 14(14):2063-73. PubMed ID: 15944198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.