These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 23243057)

  • 1. Triptolide inhibits MDM2 and induces apoptosis in acute lymphoblastic leukemia cells through a p53-independent pathway.
    Huang M; Zhang H; Liu T; Tian D; Gu L; Zhou M
    Mol Cancer Ther; 2013 Feb; 12(2):184-94. PubMed ID: 23243057
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Triptolide induces apoptosis of gastric cancer cells via inhibiting the overexpression of MDM2.
    Wang BY; Cao J; Chen JW; Liu QY
    Med Oncol; 2014 Nov; 31(11):270. PubMed ID: 25280518
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5.
    Carter BZ; Mak DH; Schober WD; Dietrich MF; Pinilla C; Vassilev LT; Reed JC; Andreeff M
    Blood; 2008 Apr; 111(7):3742-50. PubMed ID: 18187663
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Triptolide has anticancer and chemosensitization effects by down-regulating Akt activation through the MDM2/REST pathway in human breast cancer.
    Xiong J; Su T; Qu Z; Yang Q; Wang Y; Li J; Zhou S
    Oncotarget; 2016 Apr; 7(17):23933-46. PubMed ID: 27004407
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hsp90 inhibitor BIIB021 enhances triptolide-induced apoptosis of human T-cell acute lymphoblastic leukemia cells in vitro mainly by disrupting p53-MDM2 balance.
    Li M; Zhang X; Zhou WJ; Chen YH; Liu H; Liu L; Yang CM; Qan WB
    Acta Pharmacol Sin; 2013 Dec; 34(12):1545-53. PubMed ID: 24241349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antiproliferative and proapoptotic activities of triptolide (PG490), a natural product entering clinical trials, on primary cultures of human prostatic epithelial cells.
    Kiviharju TM; Lecane PS; Sellers RG; Peehl DM
    Clin Cancer Res; 2002 Aug; 8(8):2666-74. PubMed ID: 12171899
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Triptolide interrupts rRNA synthesis and induces the RPL23‑MDM2‑p53 pathway to repress lung cancer cells.
    Wang J; Zhang ZQ; Li FQ; Chen JN; Gong X; Cao BB; Wang W
    Oncol Rep; 2020 Jun; 43(6):1863-1874. PubMed ID: 32236588
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Triptolide induces growth inhibition and apoptosis of human laryngocarcinoma cells by enhancing p53 activities and suppressing E6-mediated p53 degradation.
    Zhao F; Huang W; Ousman T; Zhang B; Han Y; Clotaire DZ; Wang C; Chang H; Luo H; Ren X; Lei M
    PLoS One; 2013; 8(11):e80784. PubMed ID: 24244715
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Triptolide sensitizes TRAIL-induced apoptosis in prostate cancer cells via p53-mediated DR5 up-regulation.
    Xiaowen H; Yi S
    Mol Biol Rep; 2012 Sep; 39(9):8763-70. PubMed ID: 22707197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of MDM2 by nilotinib contributes to cytotoxicity in both Philadelphia-positive and negative acute lymphoblastic leukemia.
    Zhang H; Gu L; Liu T; Chiang KY; Zhou M
    PLoS One; 2014; 9(6):e100960. PubMed ID: 24968304
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells.
    Jiang XH; Wong BC; Lin MC; Zhu GH; Kung HF; Jiang SH; Yang D; Lam SK
    Oncogene; 2001 Nov; 20(55):8009-18. PubMed ID: 11753684
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low dose triptolide reverses chemoresistance in adult acute lymphoblastic leukemia cells via reactive oxygen species generation and DNA damage response disruption.
    Zhao H; Shi P; Deng M; Jiang Z; Li Y; Kannappan V; Wang W; Li P; Xu B
    Oncotarget; 2016 Dec; 7(51):85515-85528. PubMed ID: 27888802
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Degradation of MDM2 by the interaction between berberine and DAXX leads to potent apoptosis in MDM2-overexpressing cancer cells.
    Zhang X; Gu L; Li J; Shah N; He J; Yang L; Hu Q; Zhou M
    Cancer Res; 2010 Dec; 70(23):9895-904. PubMed ID: 20935220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective tumor cell killing by triptolide in p53 wild-type and p53 mutant ovarian carcinomas.
    Wu J; Li QQ; Zhou H; Lu Y; Li JM; Ma Y; Wang L; Fu T; Gong X; Weintraub M; Wu S; Ding H
    Med Oncol; 2014 Jul; 31(7):14. PubMed ID: 24880464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Triptolide induces Bcl-2 cleavage and mitochondria dependent apoptosis in p53-deficient HL-60 cells.
    Wan CK; Wang C; Cheung HY; Yang M; Fong WF
    Cancer Lett; 2006 Sep; 241(1):31-41. PubMed ID: 16316721
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells.
    Zhou GS; Hu Z; Fang HT; Zhang FX; Pan XF; Chen XQ; Hu AM; Xu L; Zhou GB
    Leuk Res; 2011 Feb; 35(2):214-8. PubMed ID: 20691473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cancer-specific enhancement of cisplatin-induced cytotoxicity with triptolide through an interaction of inactivated glycogen synthase kinase-3beta with p53.
    Matsui Y; Watanabe J; Ikegawa M; Kamoto T; Ogawa O; Nishiyama H
    Oncogene; 2008 Jul; 27(33):4603-14. PubMed ID: 18391982
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of triptolide from Tripterygium wilfordii on ERalpha and p53 expression in two human breast cancer cell lines.
    Liu J; Jiang Z; Xiao J; Zhang Y; Lin S; Duan W; Yao J; Liu C; Huang X; Wang T; Liang Z; Wang R; Zhang S; Zhang L
    Phytomedicine; 2009 Nov; 16(11):1006-13. PubMed ID: 19524422
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An MDM2 degrader shows potent cytotoxicity to MDM2-overexpressing acute lymphoblastic leukemia cells with minimal toxicity to normal cells/tissues.
    Liu T; Gu L; Mui A; Wu Z; Albadari N; Li W; Zhou M
    Cancer Lett; 2024 Aug; 598():217126. PubMed ID: 39053726
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Triptolide induces apoptosis in endometrial cancer via a p53‑independent mitochondrial pathway.
    Wang XF; Zhao YB; Wu Q; Sun ZH; Li HJ
    Mol Med Rep; 2014 Jan; 9(1):39-44. PubMed ID: 24213358
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.