BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 23243060)

  • 1. Induction of endoplasmic reticulum stress by sorafenib and activation of NF-κB by lestaurtinib as a novel resistance mechanism in Hodgkin lymphoma cell lines.
    Holz MS; Janning A; Renné C; Gattenlöhner S; Spieker T; Bräuninger A
    Mol Cancer Ther; 2013 Feb; 12(2):173-83. PubMed ID: 23243060
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Perifosine and sorafenib combination induces mitochondrial cell death and antitumor effects in NOD/SCID mice with Hodgkin lymphoma cell line xenografts.
    Locatelli SL; Giacomini A; Guidetti A; Cleris L; Mortarini R; Anichini A; Gianni AM; Carlo-Stella C
    Leukemia; 2013 Aug; 27(8):1677-87. PubMed ID: 23360848
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sorafenib-mediated targeting of the AAA⁺ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death.
    Yi P; Higa A; Taouji S; Bexiga MG; Marza E; Arma D; Castain C; Le Bail B; Simpson JC; Rosenbaum J; Balabaud C; Bioulac-Sage P; Blanc JF; Chevet E
    Mol Cancer Ther; 2012 Dec; 11(12):2610-20. PubMed ID: 23041544
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Multiple mechanisms mediate resistance to sorafenib in urothelial cancer.
    Knievel J; Schulz WA; Greife A; Hader C; Lübke T; Schmitz I; Albers P; Niegisch G
    Int J Mol Sci; 2014 Nov; 15(11):20500-17. PubMed ID: 25387078
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hodgkin disease: pharmacologic intervention of the CD40-NF kappa B pathway by a protease inhibitor.
    Annunziata CM; Safiran YJ; Irving SG; Kasid UN; Cossman J
    Blood; 2000 Oct; 96(8):2841-8. PubMed ID: 11023520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells.
    Pal HC; Baxter RD; Hunt KM; Agarwal J; Elmets CA; Athar M; Afaq F
    Oncotarget; 2015 Sep; 6(29):28296-311. PubMed ID: 26299806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress.
    Zhai B; Hu F; Yan H; Zhao D; Jin X; Fang T; Pan S; Sun X; Xu L
    PLoS One; 2015; 10(9):e0138485. PubMed ID: 26381511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells.
    Schwarzer R; Dörken B; Jundt F
    Leukemia; 2012 Apr; 26(4):806-13. PubMed ID: 21946908
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sorafenib enhances proteasome inhibitor-mediated cytotoxicity via inhibition of unfolded protein response and keratin phosphorylation.
    Honma Y; Harada M
    Exp Cell Res; 2013 Aug; 319(14):2166-78. PubMed ID: 23727131
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Notch and NF-κB signaling pathways in the biology of classical Hodgkin lymphoma.
    Schwarzer R; Jundt F
    Curr Mol Med; 2011 Apr; 11(3):236-45. PubMed ID: 21375490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rhabdomyosarcoma cells are susceptible to cell death by LDK378 alone or in combination with sorafenib independently of anaplastic lymphoma kinase status.
    Dolgikh N; Fulda S
    Anticancer Drugs; 2017 Nov; 28(10):1118-1125. PubMed ID: 29045271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells.
    Horie R; Watanabe T; Morishita Y; Ito K; Ishida T; Kanegae Y; Saito I; Higashihara M; Mori S; Kadin ME; Watanabe T
    Oncogene; 2002 Apr; 21(16):2493-503. PubMed ID: 11971184
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic anti-proliferative effect of metformin and sorafenib on growth of anaplastic thyroid cancer cells and their stem cells.
    Chen G; Nicula D; Renko K; Derwahl M
    Oncol Rep; 2015 Apr; 33(4):1994-2000. PubMed ID: 25683253
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells.
    Izban KF; Ergin M; Huang Q; Qin JZ; Martinez RL; Schnitzer B; Ni H; Nickoloff BJ; Alkan S
    Mod Pathol; 2001 Apr; 14(4):297-310. PubMed ID: 11301346
    [TBL] [Abstract][Full Text] [Related]  

  • 15. JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma.
    Watanabe M; Sasaki M; Itoh K; Higashihara M; Umezawa K; Kadin ME; Abraham LJ; Watanabe T; Horie R
    Cancer Res; 2005 Sep; 65(17):7628-34. PubMed ID: 16140928
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors.
    Nguyen B; Williams AB; Young DJ; Ma H; Li L; Levis M; Brown P; Small D
    Oncotarget; 2017 Feb; 8(7):10931-10944. PubMed ID: 28077790
    [TBL] [Abstract][Full Text] [Related]  

  • 17. c-FLIP mediates resistance of Hodgkin/Reed-Sternberg cells to death receptor-induced apoptosis.
    Mathas S; Lietz A; Anagnostopoulos I; Hummel F; Wiesner B; Janz M; Jundt F; Hirsch B; Jöhrens-Leder K; Vornlocher HP; Bommert K; Stein H; Dörken B
    J Exp Med; 2004 Apr; 199(8):1041-52. PubMed ID: 15078899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sorafenib inhibits intracellular signaling pathways and induces cell cycle arrest and cell death in thyroid carcinoma cells irrespective of histological origin or BRAF mutational status.
    Broecker-Preuss M; Müller S; Britten M; Worm K; Schmid KW; Mann K; Fuhrer D
    BMC Cancer; 2015 Mar; 15():184. PubMed ID: 25879531
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The kinase inhibitor sorafenib induces cell death through a process involving induction of endoplasmic reticulum stress.
    Rahmani M; Davis EM; Crabtree TR; Habibi JR; Nguyen TK; Dent P; Grant S
    Mol Cell Biol; 2007 Aug; 27(15):5499-513. PubMed ID: 17548474
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model.
    Chen JC; Chuang HY; Hsu FT; Chen YC; Chien YC; Hwang JJ
    Oncotarget; 2016 Dec; 7(51):85450-85463. PubMed ID: 27863427
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.