These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 23245753)

  • 1. Synthesis and biological evaluation of 4-hydroxy-4-(4-methoxyphenyl)-substituted proline and pyrrolidin-2-ylacetic acid derivatives as GABA uptake inhibitors.
    Zhao X; Pabel J; Höfner GC; Wanner KT
    Bioorg Med Chem; 2013 Jan; 21(2):470-84. PubMed ID: 23245753
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.
    Hack S; Wörlein B; Höfner G; Pabel J; Wanner KT
    Eur J Med Chem; 2011 May; 46(5):1483-98. PubMed ID: 21353350
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New highly potent GABA uptake inhibitors selective for GAT-1 and GAT-3 derived from (R)- and (S)-proline and homologous pyrrolidine-2-alkanoic acids.
    Fülep GH; Hoesl CE; Höfner G; Wanner KT
    Eur J Med Chem; 2006 Jul; 41(7):809-24. PubMed ID: 16766089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.
    Zhuang W; Zhao X; Zhao G; Guo L; Lian Y; Zhou J; Fang D
    Bioorg Med Chem; 2009 Sep; 17(18):6540-6. PubMed ID: 19703775
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.
    Pizzi DA; Leslie CP; Di Fabio R; Seri C; Bernasconi G; Squaglia M; Carnevale G; Falchi A; Greco E; Mangiarini L; Negri M
    Bioorg Med Chem Lett; 2011 Jan; 21(1):602-5. PubMed ID: 21134748
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-Substituted 4-hydroxybutanamides as potential inhibitors of γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.
    Kowalczyk P; Sałat K; Höfner GC; Guzior N; Filipek B; Wanner KT; Kulig K
    Bioorg Med Chem; 2013 Sep; 21(17):5154-67. PubMed ID: 23859778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.
    Faust MR; Höfner G; Pabel J; Wanner KT
    Eur J Med Chem; 2010 Jun; 45(6):2453-66. PubMed ID: 20219271
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of new derivatives of 2-substituted 4-hydroxybutanamides as GABA uptake inhibitors.
    Kulig K; Więckowski K; Więckowska A; Gajda J; Pochwat B; Höfner GC; Wanner KT; Malawska B
    Eur J Med Chem; 2011 Jan; 46(1):183-90. PubMed ID: 21111516
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.
    Quandt G; Höfner G; Wanner KT
    Bioorg Med Chem; 2013 Jun; 21(11):3363-78. PubMed ID: 23598250
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of N-substituted acyclic β-amino acids and their investigation as GABA uptake inhibitors.
    Sitka I; Allmendinger L; Fülep G; Höfner G; Wanner KT
    Eur J Med Chem; 2013 Jul; 65():487-99. PubMed ID: 23770450
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors.
    Tóth K; Höfner G; Wanner KT
    Bioorg Med Chem; 2018 Jul; 26(12):3668-3687. PubMed ID: 29886082
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids.
    Steffan T; Renukappa-Gutke T; Höfner G; Wanner KT
    Bioorg Med Chem; 2015 Mar; 23(6):1284-306. PubMed ID: 25698617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation and screening of oxime libraries addressing the neuronal GABA transporter GAT1.
    Kern FT; Wanner KT
    ChemMedChem; 2015 Feb; 10(2):396-410. PubMed ID: 25369775
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents.
    Lutz T; Wein T; Höfner G; Wanner KT
    ChemMedChem; 2017 Mar; 12(5):362-371. PubMed ID: 28125164
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aminomethyltetrazoles as potential inhibitors of the γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.
    Schaffert ES; Höfner G; Wanner KT
    Bioorg Med Chem; 2011 Nov; 19(21):6492-504. PubMed ID: 21940173
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.
    Kerscher-Hack S; Renukappa-Gutke T; Höfner G; Wanner KT
    Eur J Med Chem; 2016 Nov; 124():852-880. PubMed ID: 27654218
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and pharmacological evaluation of new 4,4-diphenylbut-3-enyl derivatives of 4-hydroxybutanamides as GABA uptake inhibitors.
    Kowalczyk P; Höfner G; Wanner KT; Kulig K
    Acta Pol Pharm; 2012; 69(1):157-60. PubMed ID: 22574521
    [No Abstract]   [Full Text] [Related]  

  • 18. Development of an (S)-1-{2-[tris(4-methoxyphenyl)methoxy]ethyl}piperidine-3-carboxylic acid [(S)-SNAP-5114] carba analogue inhibitor for murine γ-aminobutyric acid transporter type 4.
    Pabel J; Faust M; Prehn C; Wörlein B; Allmendinger L; Höfner G; Wanner KT
    ChemMedChem; 2012 Jul; 7(7):1245-55. PubMed ID: 22544452
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
    Zaręba P; Gryzło B; Malawska K; Sałat K; Höfner GC; Nowaczyk A; Fijałkowski Ł; Rapacz A; Podkowa A; Furgała A; Żmudzki P; Wanner KT; Malawska B; Kulig K
    Eur J Med Chem; 2020 Feb; 188():111920. PubMed ID: 31901745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Library screening by means of mass spectrometry (MS) binding assays-exemplarily demonstrated for a pseudostatic library addressing γ-aminobutyric acid (GABA) transporter 1 (GAT1).
    Sindelar M; Wanner KT
    ChemMedChem; 2012 Sep; 7(9):1678-90. PubMed ID: 22689508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.