268 related articles for article (PubMed ID: 23248303)
1. N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.
Wang Z; Liu Y; Takahashi M; Van Hook K; Kampa-Schittenhelm KM; Sheppard BC; Sears RC; Stork PJ; Lopez CD
Proc Natl Acad Sci U S A; 2013 Jan; 110(1):312-7. PubMed ID: 23248303
[TBL] [Abstract][Full Text] [Related]
2. ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold.
Posada IM; Serulla M; Zhou Y; Oetken-Lindholm C; Abankwa D; Lectez B
PLoS One; 2016; 11(7):e0159677. PubMed ID: 27437940
[TBL] [Abstract][Full Text] [Related]
3. Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.
Garnett MJ; Rana S; Paterson H; Barford D; Marais R
Mol Cell; 2005 Dec; 20(6):963-9. PubMed ID: 16364920
[TBL] [Abstract][Full Text] [Related]
4. Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization.
Yasuda S; Kai M; Imai S; Takeishi K; Taketomi A; Toyota M; Kanoh H; Sakane F
J Biol Chem; 2009 Oct; 284(43):29559-70. PubMed ID: 19710016
[TBL] [Abstract][Full Text] [Related]
5. Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.
Rajalingam K; Wunder C; Brinkmann V; Churin Y; Hekman M; Sievers C; Rapp UR; Rudel T
Nat Cell Biol; 2005 Aug; 7(8):837-43. PubMed ID: 16041367
[TBL] [Abstract][Full Text] [Related]
6. Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity.
Ishii N; Harada N; Joseph EW; Ohara K; Miura T; Sakamoto H; Matsuda Y; Tomii Y; Tachibana-Kondo Y; Iikura H; Aoki T; Shimma N; Arisawa M; Sowa Y; Poulikakos PI; Rosen N; Aoki Y; Sakai T
Cancer Res; 2013 Jul; 73(13):4050-4060. PubMed ID: 23667175
[TBL] [Abstract][Full Text] [Related]
7. The tumour suppressor DiRas3 interacts with C-RAF and downregulates MEK activity to restrict cell migration.
Klingauf M; Beck M; Berge U; Turgay Y; Heinzer S; Horvath P; Kroschewski R
Biol Cell; 2013 Feb; 105(2):91-107. PubMed ID: 23157514
[TBL] [Abstract][Full Text] [Related]
8. A dimerization-dependent mechanism drives RAF catalytic activation.
Rajakulendran T; Sahmi M; Lefrançois M; Sicheri F; Therrien M
Nature; 2009 Sep; 461(7263):542-5. PubMed ID: 19727074
[TBL] [Abstract][Full Text] [Related]
9. The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.
Kortum RL; Johnson HJ; Costanzo DL; Volle DJ; Razidlo GL; Fusello AM; Shaw AS; Lewis RE
Mol Cell Biol; 2006 Mar; 26(6):2202-14. PubMed ID: 16507997
[TBL] [Abstract][Full Text] [Related]
10. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
[TBL] [Abstract][Full Text] [Related]
11. The tumor suppressor DiRas3 forms a complex with H-Ras and C-RAF proteins and regulates localization, dimerization, and kinase activity of C-RAF.
Baljuls A; Beck M; Oenel A; Robubi A; Kroschewski R; Hekman M; Rudel T; Rapp UR
J Biol Chem; 2012 Jun; 287(27):23128-40. PubMed ID: 22605333
[TBL] [Abstract][Full Text] [Related]
12. Senescence of human fibroblasts induced by oncogenic Raf.
Zhu J; Woods D; McMahon M; Bishop JM
Genes Dev; 1998 Oct; 12(19):2997-3007. PubMed ID: 9765202
[TBL] [Abstract][Full Text] [Related]
13. Induction of p38δ expression plays an essential role in oncogenic ras-induced senescence.
Kwong J; Chen M; Lv D; Luo N; Su W; Xiang R; Sun P
Mol Cell Biol; 2013 Oct; 33(19):3780-94. PubMed ID: 23878395
[TBL] [Abstract][Full Text] [Related]
14. The amino-terminal B-Raf-specific region mediates calcium-dependent homo- and hetero-dimerization of Raf.
Terai K; Matsuda M
EMBO J; 2006 Aug; 25(15):3556-64. PubMed ID: 16858395
[TBL] [Abstract][Full Text] [Related]
15. RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma.
Yang T; Zhu C; Shi Y; Shen Y; Gao Y; Zhang B; Jin R; Liu D; Ouyang Y; Liu X; Wang W; Yang P; Xu Q; Cai J; Chen D
Cancer Gene Ther; 2022 Nov; 29(11):1616-1627. PubMed ID: 35504951
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of Ras/Raf/MEK/ERK Pathway Signaling by a Stress-Induced Phospho-Regulatory Circuit.
Ritt DA; Abreu-Blanco MT; Bindu L; Durrant DE; Zhou M; Specht SI; Stephen AG; Holderfield M; Morrison DK
Mol Cell; 2016 Dec; 64(5):875-887. PubMed ID: 27889448
[TBL] [Abstract][Full Text] [Related]
17. Phosphorylation of ASPP2 by RAS/MAPK pathway is critical for its full pro-apoptotic function.
Godin-Heymann N; Wang Y; Slee E; Lu X
PLoS One; 2013; 8(12):e82022. PubMed ID: 24312625
[TBL] [Abstract][Full Text] [Related]
18. Classical RAS proteins are not essential for paradoxical ERK activation induced by RAF inhibitors.
Lai LP; Fer N; Burgan W; Wall VE; Xu B; Soppet D; Esposito D; Nissley DV; McCormick F
Proc Natl Acad Sci U S A; 2022 Feb; 119(5):. PubMed ID: 35091470
[TBL] [Abstract][Full Text] [Related]
19. ASPP1 and ASPP2 bind active RAS, potentiate RAS signalling and enhance p53 activity in cancer cells.
Wang Y; Godin-Heymann N; Dan Wang X; Bergamaschi D; Llanos S; Lu X
Cell Death Differ; 2013 Apr; 20(4):525-34. PubMed ID: 23392125
[TBL] [Abstract][Full Text] [Related]
20. A novel antiproliferative PKCα-Ras-ERK signaling axis in intestinal epithelial cells.
Kaur N; Lum MA; Lewis RE; Black AR; Black JD
J Biol Chem; 2022 Jul; 298(7):102121. PubMed ID: 35697074
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
