BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

386 related articles for article (PubMed ID: 23250396)

  • 1. IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors.
    Evdokimova V; Tognon CE; Benatar T; Yang W; Krutikov K; Pollak M; Sorensen PH; Seth A
    Sci Signal; 2012 Dec; 5(255):ra92. PubMed ID: 23250396
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.
    Denley A; Carroll JM; Brierley GV; Cosgrove L; Wallace J; Forbes B; Roberts CT
    Mol Cell Biol; 2007 May; 27(10):3569-77. PubMed ID: 17325037
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.
    Sachdev D; Li SL; Hartell JS; Fujita-Yamaguchi Y; Miller JS; Yee D
    Cancer Res; 2003 Feb; 63(3):627-35. PubMed ID: 12566306
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells.
    Ellis MJ; Leav BA; Yang Z; Rasmussen A; Pearce A; Zweibel JA; Lippman ME; Cullen KJ
    Mol Endocrinol; 1996 Mar; 10(3):286-97. PubMed ID: 8833657
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of the insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line.
    Bradley LM; Gierthy JF; Pentecost BT
    J Steroid Biochem Mol Biol; 2008 Mar; 109(1-2):185-96. PubMed ID: 18337089
    [TBL] [Abstract][Full Text] [Related]  

  • 6. IGFBP7 reduces breast tumor growth by induction of senescence and apoptosis pathways.
    Benatar T; Yang W; Amemiya Y; Evdokimova V; Kahn H; Holloway C; Seth A
    Breast Cancer Res Treat; 2012 Jun; 133(2):563-73. PubMed ID: 21997538
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Physiologic IGFBP7 levels prolong IGF1R activation in acute lymphoblastic leukemia.
    Artico LL; Laranjeira ABA; Campos LW; Corrêa JR; Zenatti PP; Carvalheira JBC; Brambilla SR; Nowill AE; Brandalise SR; Yunes JA
    Blood Adv; 2021 Sep; 5(18):3633-3646. PubMed ID: 34438446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-like growth factors inhibit dendritic cell-mediated anti-tumor immunity through regulating ERK1/2 phosphorylation and p38 dephosphorylation.
    Huang CT; Chang MC; Chen YL; Chen TC; Chen CA; Cheng WF
    Cancer Lett; 2015 Apr; 359(1):117-26. PubMed ID: 25592043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TGF-β-induced expression of IGFBP-3 regulates IGF1R signaling in human osteosarcoma cells.
    Schedlich LJ; Yenson VM; Baxter RC
    Mol Cell Endocrinol; 2013 Sep; 377(1-2):56-64. PubMed ID: 23831640
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Diversity of insulin and IGF signaling in breast cancer: Implications for therapy.
    Lero MW; Shaw LM
    Mol Cell Endocrinol; 2021 May; 527():111213. PubMed ID: 33607269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.
    Zhang H; Pelzer AM; Kiang DT; Yee D
    Cancer Res; 2007 Jan; 67(1):391-7. PubMed ID: 17210722
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IGF-II is up-regulated and myofibres are hypertrophied in regenerating soleus of mice lacking FGF6.
    Armand AS; Lécolle S; Launay T; Pariset C; Fiore F; Della Gaspera B; Birnbaum D; Chanoine C; Charbonnier F
    Exp Cell Res; 2004 Jul; 297(1):27-38. PubMed ID: 15194422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An integrin binding-defective mutant of insulin-like growth factor-1 (R36E/R37E IGF1) acts as a dominant-negative antagonist of the IGF1 receptor (IGF1R) and suppresses tumorigenesis but still binds to IGF1R.
    Fujita M; Ieguchi K; Cedano-Prieto DM; Fong A; Wilkerson C; Chen JQ; Wu M; Lo SH; Cheung AT; Wilson MD; Cardiff RD; Borowsky AD; Takada YK; Takada Y
    J Biol Chem; 2013 Jul; 288(27):19593-603. PubMed ID: 23696648
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GIPC mediates the generation of reactive oxygen species and the regulation of cancer cell proliferation by insulin-like growth factor-1/IGF-1R signaling.
    Choi JS; Paek AR; Kim SY; You HJ
    Cancer Lett; 2010 Aug; 294(2):254-63. PubMed ID: 20206441
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma.
    Cookman CJ; Belcher SM
    Endocrinology; 2015 Jul; 156(7):2395-408. PubMed ID: 25885794
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin-like growth factor binding protein-4 and -5 modulate ligand-dependent estrogen receptor-α activation in breast cancer cells in an IGF-independent manner.
    Hermani A; Shukla A; Medunjanin S; Werner H; Mayer D
    Cell Signal; 2013 Jun; 25(6):1395-402. PubMed ID: 23499909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
    Burtrum D; Zhu Z; Lu D; Anderson DM; Prewett M; Pereira DS; Bassi R; Abdullah R; Hooper AT; Koo H; Jimenez X; Johnson D; Apblett R; Kussie P; Bohlen P; Witte L; Hicklin DJ; Ludwig DL
    Cancer Res; 2003 Dec; 63(24):8912-21. PubMed ID: 14695208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role for membrane and secreted insulin-like growth factor-binding protein-2 in the regulation of insulin-like growth factor action in lung tumors.
    Reeve JG; Morgan J; Schwander J; Bleehen NM
    Cancer Res; 1993 Oct; 53(19):4680-5. PubMed ID: 7691401
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential signaling activation by insulin and insulin-like growth factors I and II upon binding to insulin receptor isoform A.
    Sacco A; Morcavallo A; Pandini G; Vigneri R; Belfiore A
    Endocrinology; 2009 Aug; 150(8):3594-602. PubMed ID: 19443570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
    Kaplan PJ; Mohan S; Cohen P; Foster BA; Greenberg NM
    Cancer Res; 1999 May; 59(9):2203-9. PubMed ID: 10232609
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.