BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 23251397)

  • 1. Structures of the human poly (ADP-ribose) glycohydrolase catalytic domain confirm catalytic mechanism and explain inhibition by ADP-HPD derivatives.
    Tucker JA; Bennett N; Brassington C; Durant ST; Hassall G; Holdgate G; McAlister M; Nissink JW; Truman C; Watson M
    PLoS One; 2012; 7(12):e50889. PubMed ID: 23251397
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase.
    Slade D; Dunstan MS; Barkauskaite E; Weston R; Lafite P; Dixon N; Ahel M; Leys D; Ahel I
    Nature; 2011 Sep; 477(7366):616-20. PubMed ID: 21892188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of an inhibitor binding site of poly(ADP-ribose) glycohydrolase.
    Koh DW; Patel CN; Ramsinghani S; Slama JT; Oliveira MA; Jacobson MK
    Biochemistry; 2003 May; 42(17):4855-63. PubMed ID: 12718526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase.
    Wang Z; Gagné JP; Poirier GG; Xu W
    PLoS One; 2014; 9(1):e86010. PubMed ID: 24465839
    [TBL] [Abstract][Full Text] [Related]  

  • 5. New Insights into the Roles of NAD+-Poly(ADP-ribose) Metabolism and Poly(ADP-ribose) Glycohydrolase.
    Tanuma S; Sato A; Oyama T; Yoshimori A; Abe H; Uchiumi F
    Curr Protein Pept Sci; 2016; 17(7):668-682. PubMed ID: 27817743
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of novel poly(ADP-ribose) glycohydrolase inhibitors by a quantitative assay system using dot-blot with anti-poly(ADP-ribose).
    Okita N; Ashizawa D; Ohta R; Abe H; Tanuma S
    Biochem Biophys Res Commun; 2010 Feb; 392(4):485-9. PubMed ID: 20079708
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase.
    Koh DW; Coyle DL; Mehta N; Ramsinghani S; Kim H; Slama JT; Jacobson MK
    J Med Chem; 2003 Sep; 46(20):4322-32. PubMed ID: 13678410
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Theoretical study on the degradation of ADP-ribose polymer catalyzed by poly(ADP-ribose) glycohydrolase.
    Hou Q; Hu X; Sheng X; Liu Y; Liu C
    J Mol Graph Model; 2013 May; 42():26-31. PubMed ID: 23524370
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors.
    Brosey CA; Houl JH; Katsonis P; Balapiti-Modarage LPF; Bommagani S; Arvai A; Moiani D; Bacolla A; Link T; Warden LS; Lichtarge O; Jones DE; Ahmed Z; Tainer JA
    Prog Biophys Mol Biol; 2021 Aug; 163():171-186. PubMed ID: 33636189
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bacterial production of recombinant human poly(ADP-ribose) glycohydrolase.
    Okita N; Ohta R; Ashizawa D; Yamada Y; Abe H; Abe T; Tanuma S
    Protein Expr Purif; 2011 Feb; 75(2):230-5. PubMed ID: 20884351
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Syntheses of photoactive analogues of adenosine diphosphate (hydroxymethyl)pyrrolidinediol and photoaffinity labeling of poly(ADP-ribose) glycohydrolase.
    Ramsinghani S; Koh DW; Amé JC; Strohm M; Jacobson MK; Slama JT
    Biochemistry; 1998 May; 37(21):7801-12. PubMed ID: 9601041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification and characterization of a mammalian 39-kDa poly(ADP-ribose) glycohydrolase.
    Oka S; Kato J; Moss J
    J Biol Chem; 2006 Jan; 281(2):705-13. PubMed ID: 16278211
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain.
    Patel CN; Koh DW; Jacobson MK; Oliveira MA
    Biochem J; 2005 Jun; 388(Pt 2):493-500. PubMed ID: 15658938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol.
    Slama JT; Aboul-Ela N; Goli DM; Cheesman BV; Simmons AM; Jacobson MK
    J Med Chem; 1995 Jan; 38(2):389-93. PubMed ID: 7830282
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mono-galloyl glucose derivatives are potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP-1-dependent cell death.
    Formentini L; Arapistas P; Pittelli M; Jacomelli M; Pitozzi V; Menichetti S; Romani A; Giovannelli L; Moroni F; Chiarugi A
    Br J Pharmacol; 2008 Dec; 155(8):1235-49. PubMed ID: 18806807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A high-throughput screening-compatible homogeneous time-resolved fluorescence assay measuring the glycohydrolase activity of human poly(ADP-ribose) glycohydrolase.
    Stowell AI; James DI; Waddell ID; Bennett N; Truman C; Hardern IM; Ogilvie DJ
    Anal Biochem; 2016 Jun; 503():58-64. PubMed ID: 27036617
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol.
    Slama JT; Aboul-Ela N; Jacobson MK
    J Med Chem; 1995 Oct; 38(21):4332-6. PubMed ID: 7473561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Altered poly(ADP-ribose) metabolism impairs cellular responses to genotoxic stress in a hypomorphic mutant of poly(ADP-ribose) glycohydrolase.
    Gao H; Coyle DL; Meyer-Ficca ML; Meyer RG; Jacobson EL; Wang ZQ; Jacobson MK
    Exp Cell Res; 2007 Mar; 313(5):984-96. PubMed ID: 17276427
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Roles of poly(ADP-ribose) glycohydrolase in DNA damage and apoptosis.
    Feng X; Koh DW
    Int Rev Cell Mol Biol; 2013; 304():227-81. PubMed ID: 23809438
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells.
    Feng X; Koh DW
    Int J Oncol; 2013 Feb; 42(2):749-56. PubMed ID: 23254695
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.