172 related articles for article (PubMed ID: 23256685)
1. Ligand-controlled assembly of hexamers, dihexamers, and linear multihexamer structures by the engineered acylated insulin degludec.
Steensgaard DB; Schluckebier G; Strauss HM; Norrman M; Thomsen JK; Friderichsen AV; Havelund S; Jonassen I
Biochemistry; 2013 Jan; 52(2):295-309. PubMed ID: 23256685
[TBL] [Abstract][Full Text] [Related]
2. Investigation of the Physico-Chemical Properties that Enable Co-Formulation of Basal Insulin Degludec with Fast-Acting Insulin Aspart.
Havelund S; Ribel U; Hubálek F; Hoeg-Jensen T; Wahlund PO; Jonassen I
Pharm Res; 2015 Jul; 32(7):2250-8. PubMed ID: 25563978
[TBL] [Abstract][Full Text] [Related]
3. Small angle X-ray scattering-based elucidation of the self-association mechanism of human insulin analogue lys(B29)(N(ε)ω-carboxyheptadecanoyl) des(B30).
Jensen MH; Wahlund PO; Toft KN; Jacobsen JK; Steensgaard DB; van de Weert M; Havelund S; Vestergaard B
Biochemistry; 2013 Jan; 52(2):282-94. PubMed ID: 23256662
[TBL] [Abstract][Full Text] [Related]
4. Oligomerization of Pharmaceutically Relevant Insulin Analogues for Varying Concentration and Salinity Revealed by Small-Angle X-ray Scattering.
Jensen GV; Rosenmejer KR; Huda P; Arleth L
Mol Pharm; 2021 Sep; 18(9):3272-3280. PubMed ID: 34351780
[TBL] [Abstract][Full Text] [Related]
5. Metal ion controlled self-assembly of a chemically reengineered protein drug studied by small-angle X-ray scattering.
Nygaard J; Munch HK; Thulstrup PW; Christensen NJ; Hoeg-Jensen T; Jensen KJ; Arleth L
Langmuir; 2012 Aug; 28(33):12159-70. PubMed ID: 22853842
[TBL] [Abstract][Full Text] [Related]
6. Binding of phenol to R6 insulin hexamers.
Berchtold H; Hilgenfeld R
Biopolymers; 1999; 51(2):165-72. PubMed ID: 10397800
[TBL] [Abstract][Full Text] [Related]
7. Zinc-ligand interactions modulate assembly and stability of the insulin hexamer -- a review.
Dunn MF
Biometals; 2005 Aug; 18(4):295-303. PubMed ID: 16158220
[TBL] [Abstract][Full Text] [Related]
8. Structure and dynamics of a protein assembly. 1H-NMR studies of the 36 kDa R6 insulin hexamer.
Jacoby E; Hua QX; Stern AS; Frank BH; Weiss MA
J Mol Biol; 1996 Apr; 258(1):136-57. PubMed ID: 8613983
[TBL] [Abstract][Full Text] [Related]
9. Design of the novel protraction mechanism of insulin degludec, an ultra-long-acting basal insulin.
Jonassen I; Havelund S; Hoeg-Jensen T; Steensgaard DB; Wahlund PO; Ribel U
Pharm Res; 2012 Aug; 29(8):2104-14. PubMed ID: 22485010
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of stabilization of the insulin hexamer through allosteric ligand interactions.
Rahuel-Clermont S; French CA; Kaarsholm NC; Dunn MF; Chou CI
Biochemistry; 1997 May; 36(19):5837-45. PubMed ID: 9153424
[TBL] [Abstract][Full Text] [Related]
11. Structural asymmetry and half-site reactivity in the T to R allosteric transition of the insulin hexamer.
Brzović PS; Choi WE; Borchardt D; Kaarsholm NC; Dunn MF
Biochemistry; 1994 Nov; 33(44):13057-69. PubMed ID: 7947711
[TBL] [Abstract][Full Text] [Related]
12. Hierarchical modeling of phenolic ligand binding to 2Zn--insulin hexamers.
Birnbaum DT; Dodd SW; Saxberg BE; Varshavsky AD; Beals JM
Biochemistry; 1996 Apr; 35(17):5366-78. PubMed ID: 8611526
[TBL] [Abstract][Full Text] [Related]
13. Self-association of long-acting insulin analogues studied by size exclusion chromatography coupled to multi-angle light scattering.
Jensen MH; Wahlund PO; Jacobsen JK; Vestergaard B; van de Weert M; Havelund S
J Chromatogr B Analyt Technol Biomed Life Sci; 2011 Oct; 879(28):2945-51. PubMed ID: 21937288
[TBL] [Abstract][Full Text] [Related]
14. Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting human insulins.
Whittingham JL; Jonassen I; Havelund S; Roberts SM; Dodson EJ; Verma CS; Wilkinson AJ; Dodson GG
Biochemistry; 2004 May; 43(20):5987-95. PubMed ID: 15147182
[TBL] [Abstract][Full Text] [Related]
15. Carboxylate ions are strong allosteric ligands for the HisB10 sites of the R-state insulin hexamer.
Huang ST; Choi WE; Bloom C; Leuenberger M; Dunn MF
Biochemistry; 1997 Aug; 36(32):9878-88. PubMed ID: 9245420
[TBL] [Abstract][Full Text] [Related]
16. Structural Insight into the Self-Assembly of a Pharmaceutically Optimized Insulin Analogue Obtained by Small-Angle X-ray Scattering.
Dreyer LS; Nygaard J; Malik L; Hoeg-Jensen T; Høiberg-Nielsen R; Arleth L
Mol Pharm; 2020 Aug; 17(8):2809-2820. PubMed ID: 32579369
[TBL] [Abstract][Full Text] [Related]
17. Role of metal ions in the T- to R-allosteric transition in the insulin hexamer.
Kadima W
Biochemistry; 1999 Oct; 38(41):13443-52. PubMed ID: 10521251
[TBL] [Abstract][Full Text] [Related]
18. Changes in secondary structure follow the dissociation of human insulin hexamers: a circular dichroism study.
Melberg SG; Johnson WC
Proteins; 1990; 8(3):280-6. PubMed ID: 2281088
[TBL] [Abstract][Full Text] [Related]
19. Solution structures of long-acting insulin analogues and their complexes with albumin.
Ryberg LA; Sønderby P; Barrientos F; Bukrinski JT; Peters GHJ; Harris P
Acta Crystallogr D Struct Biol; 2019 Mar; 75(Pt 3):272-282. PubMed ID: 30950398
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of a prolonged-acting insulin with albumin-binding properties.
Whittingham JL; Havelund S; Jonassen I
Biochemistry; 1997 Mar; 36(10):2826-31. PubMed ID: 9062110
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
