BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

454 related articles for article (PubMed ID: 23258409)

  • 1. Olefin cyclopropanation via carbene transfer catalyzed by engineered cytochrome P450 enzymes.
    Coelho PS; Brustad EM; Kannan A; Arnold FH
    Science; 2013 Jan; 339(6117):307-10. PubMed ID: 23258409
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Non-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins.
    Heel T; McIntosh JA; Dodani SC; Meyerowitz JT; Arnold FH
    Chembiochem; 2014 Nov; 15(17):2556-62. PubMed ID: 25294253
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Highly Diastereo- and Enantioselective Synthesis of Nitrile-Substituted Cyclopropanes by Myoglobin-Mediated Carbene Transfer Catalysis.
    Chandgude AL; Fasan R
    Angew Chem Int Ed Engl; 2018 Nov; 57(48):15852-15856. PubMed ID: 30300955
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improved cyclopropanation activity of histidine-ligated cytochrome P450 enables the enantioselective formal synthesis of levomilnacipran.
    Wang ZJ; Renata H; Peck NE; Farwell CC; Coelho PS; Arnold FH
    Angew Chem Int Ed Engl; 2014 Jun; 53(26):6810-3. PubMed ID: 24802161
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutating a Highly Conserved Residue in Diverse Cytochrome P450s Facilitates Diastereoselective Olefin Cyclopropanation.
    Gober JG; Rydeen AE; Gibson-O'Grady EJ; Leuthaeuser JB; Fetrow JS; Brustad EM
    Chembiochem; 2016 Mar; 17(5):394-7. PubMed ID: 26690878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo.
    Coelho PS; Wang ZJ; Ener ME; Baril SA; Kannan A; Arnold FH; Brustad EM
    Nat Chem Biol; 2013 Aug; 9(8):485-7. PubMed ID: 23792734
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Highly diastereoselective and enantioselective olefin cyclopropanation using engineered myoglobin-based catalysts.
    Bordeaux M; Tyagi V; Fasan R
    Angew Chem Int Ed Engl; 2015 Feb; 54(6):1744-8. PubMed ID: 25538035
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Navigating the Unnatural Reaction Space: Directed Evolution of Heme Proteins for Selective Carbene and Nitrene Transfer.
    Yang Y; Arnold FH
    Acc Chem Res; 2021 Mar; 54(5):1209-1225. PubMed ID: 33491448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 'Carbene radicals' in Co(II)(por)-catalyzed olefin cyclopropanation.
    Dzik WI; Xu X; Zhang XP; Reek JN; de Bruin B
    J Am Chem Soc; 2010 Aug; 132(31):10891-902. PubMed ID: 20681723
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene.
    Tinoco A; Steck V; Tyagi V; Fasan R
    J Am Chem Soc; 2017 Apr; 139(15):5293-5296. PubMed ID: 28366001
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclopropanations via Heme Carbenes: Basic Mechanism and Effects of Carbene Substituent, Protein Axial Ligand, and Porphyrin Substitution.
    Wei Y; Tinoco A; Steck V; Fasan R; Zhang Y
    J Am Chem Soc; 2018 Feb; 140(5):1649-1662. PubMed ID: 29268614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gold(I)-catalyzed intermolecular cyclopropanation of enynes with alkenes: trapping of two different gold carbenes.
    López S; Herrero-Gómez E; Pérez-Galán P; Nieto-Oberhuber C; Echavarren AM
    Angew Chem Int Ed Engl; 2006 Sep; 45(36):6029-32. PubMed ID: 16900550
    [No Abstract]   [Full Text] [Related]  

  • 13. Theoretical Insights into the Mechanism and Stereoselectivity of Olefin Cyclopropanation Catalyzed by Two Engineered Cytochrome P450 Enzymes.
    Su H; Ma G; Liu Y
    Inorg Chem; 2018 Sep; 57(18):11738-11745. PubMed ID: 30156099
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Theoretical study on the mechanism of the [2+1] thermal cycloaddition between alkenes and stable singlet (phosphino)(silyl)carbenes.
    Lecea B; Ayerbe M; Arrieta A; Cossío FP; Branchadell V; Ortuño RM; Baceiredo A
    J Org Chem; 2007 Jan; 72(2):357-66. PubMed ID: 17221950
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enantioselective cyclopropanation of enals by oxidative N-heterocyclic carbene catalysis.
    Biswas A; De Sarkar S; Tebben L; Studer A
    Chem Commun (Camb); 2012 May; 48(42):5190-2. PubMed ID: 22513712
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Gold(I)-catalyzed stereoselective olefin cyclopropanation.
    Johansson MJ; Gorin DJ; Staben ST; Toste FD
    J Am Chem Soc; 2005 Dec; 127(51):18002-3. PubMed ID: 16366541
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Formal Diels-Alder reactions of chalcones and formylcyclopropanes catalyzed by chiral N-heterocyclic carbenes.
    Lv H; Mo J; Fang X; Chi YR
    Org Lett; 2011 Oct; 13(19):5366-9. PubMed ID: 21877756
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Catalytic C(sp
    Griffin JR; Wendell CI; Garwin JA; White MC
    J Am Chem Soc; 2017 Oct; 139(39):13624-13627. PubMed ID: 28898063
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of donor-acceptor alkynylcyclopropanes by diastereoselective cyclopropanation of electron-deficient alkenes with alkoxyalkynyl Fischer carbene complexes.
    Barluenga J; Fernández-Rodríguez MA; García-García P; Aguilar E; Merino I
    Chemistry; 2005 Dec; 12(1):303-13. PubMed ID: 16294347
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The nature of chemical innovation: new enzymes by evolution.
    Arnold FH
    Q Rev Biophys; 2015 Nov; 48(4):404-10. PubMed ID: 26537398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.