BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 23261602)

  • 1. Catalysis uncoupling in a glutamine amidotransferase bienzyme by unblocking the glutaminase active site.
    List F; Vega MC; Razeto A; Häger MC; Sterner R; Wilmanns M
    Chem Biol; 2012 Dec; 19(12):1589-99. PubMed ID: 23261602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase.
    Myers RS; Amaro RE; Luthey-Schulten ZA; Davisson VJ
    Biochemistry; 2005 Sep; 44(36):11974-85. PubMed ID: 16142895
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex and the free enzyme.
    Chaudhuri BN; Lange SC; Myers RS; Davisson VJ; Smith JL
    Biochemistry; 2003 Jun; 42(23):7003-12. PubMed ID: 12795595
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex.
    Douangamath A; Walker M; Beismann-Driemeyer S; Vega-Fernandez MC; Sterner R; Wilmanns M
    Structure; 2002 Feb; 10(2):185-93. PubMed ID: 11839304
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Subunit interactions and glutamine utilization by Escherichia coli imidazole glycerol phosphate synthase.
    Klem TJ; Chen Y; Davisson VJ
    J Bacteriol; 2001 Feb; 183(3):989-96. PubMed ID: 11208798
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Conformational changes in ammonia-channeling glutamine amidotransferases.
    Mouilleron S; Golinelli-Pimpaneau B
    Curr Opin Struct Biol; 2007 Dec; 17(6):653-64. PubMed ID: 17951049
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling.
    Omi R; Mizuguchi H; Goto M; Miyahara I; Hayashi H; Kagamiyama H; Hirotsu K
    J Biochem; 2002 Nov; 132(5):759-65. PubMed ID: 12417026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. "Pinching" the ammonia tunnel of CTP synthase unveils coordinated catalytic and allosteric-dependent control of ammonia passage.
    McCluskey GD; Bearne SL
    Biochim Biophys Acta Gen Subj; 2018 Dec; 1862(12):2714-2727. PubMed ID: 30251661
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites.
    Chaudhuri BN; Lange SC; Myers RS; Chittur SV; Davisson VJ; Smith JL
    Structure; 2001 Oct; 9(10):987-97. PubMed ID: 11591353
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain.
    Dossena L; Curti B; Vanoni MA
    Biochemistry; 2007 Apr; 46(15):4473-85. PubMed ID: 17373776
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase.
    Myers RS; Jensen JR; Deras IL; Smith JL; Davisson VJ
    Biochemistry; 2003 Jun; 42(23):7013-22. PubMed ID: 12795596
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Imidazole glycerol phosphate synthase from Thermotoga maritima. Quaternary structure, steady-state kinetics, and reaction mechanism of the bienzyme complex.
    Beismann-Driemeyer S; Sterner R
    J Biol Chem; 2001 Jun; 276(23):20387-96. PubMed ID: 11264293
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Channeling of ammonia in glucosamine-6-phosphate synthase.
    Teplyakov A; Obmolova G; Badet B; Badet-Denisot MA
    J Mol Biol; 2001 Nov; 313(5):1093-102. PubMed ID: 11700065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
    Wurm JP; Sung S; Kneuttinger AC; Hupfeld E; Sterner R; Wilmanns M; Sprangers R
    Nat Commun; 2021 May; 12(1):2748. PubMed ID: 33980881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural elements in IGP synthase exclude water to optimize ammonia transfer.
    Amaro RE; Myers RS; Davisson VJ; Luthey-Schulten ZA
    Biophys J; 2005 Jul; 89(1):475-87. PubMed ID: 15849257
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate binding is required for assembly of the active conformation of the catalytic site in Ntn amidotransferases: evidence from the 1.8 A crystal structure of the glutaminase domain of glucosamine 6-phosphate synthase.
    Isupov MN; Obmolova G; Butterworth S; Badet-Denisot MA; Badet B; Polikarpov I; Littlechild JA; Teplyakov A
    Structure; 1996 Jul; 4(7):801-10. PubMed ID: 8805567
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase.
    Smith AM; Brown WC; Harms E; Smith JL
    J Biol Chem; 2015 Feb; 290(9):5226-39. PubMed ID: 25568319
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lid L11 of the glutamine amidotransferase domain of CTP synthase mediates allosteric GTP activation of glutaminase activity.
    Willemoës M; Mølgaard A; Johansson E; Martinussen J
    FEBS J; 2005 Feb; 272(3):856-64. PubMed ID: 15670165
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Eukaryotic NAD+ synthetase Qns1 contains an essential, obligate intramolecular thiol glutamine amidotransferase domain related to nitrilase.
    Bieganowski P; Pace HC; Brenner C
    J Biol Chem; 2003 Aug; 278(35):33049-55. PubMed ID: 12771147
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intersubunit cross-talk in pyridoxal 5'-phosphate synthase, coordinated by the C terminus of the synthase subunit.
    Raschle T; Speziga D; Kress W; Moccand C; Gehrig P; Amrhein N; Weber-Ban E; Fitzpatrick TB
    J Biol Chem; 2009 Mar; 284(12):7706-18. PubMed ID: 19074821
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.