225 related articles for article (PubMed ID: 23262279)
1. High-throughput identification and characterization of novel, species-selective GPR35 agonists.
Neetoo-Isseljee Z; MacKenzie AE; Southern C; Jerman J; McIver EG; Harries N; Taylor DL; Milligan G
J Pharmacol Exp Ther; 2013 Mar; 344(3):568-78. PubMed ID: 23262279
[TBL] [Abstract][Full Text] [Related]
2. Antagonists of GPR35 display high species ortholog selectivity and varying modes of action.
Jenkins L; Harries N; Lappin JE; MacKenzie AE; Neetoo-Isseljee Z; Southern C; McIver EG; Nicklin SA; Taylor DL; Milligan G
J Pharmacol Exp Ther; 2012 Dec; 343(3):683-95. PubMed ID: 22967846
[TBL] [Abstract][Full Text] [Related]
3. Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13.
Jenkins L; Brea J; Smith NJ; Hudson BD; Reilly G; Bryant NJ; Castro M; Loza MI; Milligan G
Biochem J; 2010 Dec; 432(3):451-9. PubMed ID: 20919992
[TBL] [Abstract][Full Text] [Related]
4. Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
Southern C; Cook JM; Neetoo-Isseljee Z; Taylor DL; Kettleborough CA; Merritt A; Bassoni DL; Raab WJ; Quinn E; Wehrman TS; Davenport AP; Brown AJ; Green A; Wigglesworth MJ; Rees S
J Biomol Screen; 2013 Jun; 18(5):599-609. PubMed ID: 23396314
[TBL] [Abstract][Full Text] [Related]
5. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Gα₁₃ and β-arrestin-2.
Jenkins L; Alvarez-Curto E; Campbell K; de Munnik S; Canals M; Schlyer S; Milligan G
Br J Pharmacol; 2011 Feb; 162(3):733-48. PubMed ID: 20958291
[TBL] [Abstract][Full Text] [Related]
6. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity.
Zhao P; Sharir H; Kapur A; Cowan A; Geller EB; Adler MW; Seltzman HH; Reggio PH; Heynen-Genel S; Sauer M; Chung TD; Bai Y; Chen W; Caron MG; Barak LS; Abood ME
Mol Pharmacol; 2010 Oct; 78(4):560-8. PubMed ID: 20826425
[TBL] [Abstract][Full Text] [Related]
7. Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists.
Deng H; Hu H; He M; Hu J; Niu W; Ferrie AM; Fang Y
J Med Chem; 2011 Oct; 54(20):7385-96. PubMed ID: 21950657
[TBL] [Abstract][Full Text] [Related]
8. Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor.
Free RB; Chun LS; Moritz AE; Miller BN; Doyle TB; Conroy JL; Padron A; Meade JA; Xiao J; Hu X; Dulcey AE; Han Y; Duan L; Titus S; Bryant-Genevier M; Barnaeva E; Ferrer M; Javitch JA; Beuming T; Shi L; Southall NT; Marugan JJ; Sibley DR
Mol Pharmacol; 2014 Jul; 86(1):96-105. PubMed ID: 24755247
[TBL] [Abstract][Full Text] [Related]
9. beta-Arrestin recruitment assay for the identification of agonists of the sphingosine 1-phosphate receptor EDG1.
van Der Lee MM; Bras M; van Koppen CJ; Zaman GJ
J Biomol Screen; 2008 Dec; 13(10):986-98. PubMed ID: 19036707
[TBL] [Abstract][Full Text] [Related]
10. Tyrphostin analogs are GPR35 agonists.
Deng H; Hu H; Fang Y
FEBS Lett; 2011 Jun; 585(12):1957-62. PubMed ID: 21601572
[TBL] [Abstract][Full Text] [Related]
11. Identification of G protein-biased agonists that fail to recruit β-arrestin or promote internalization of the D1 dopamine receptor.
Conroy JL; Free RB; Sibley DR
ACS Chem Neurosci; 2015 Apr; 6(4):681-92. PubMed ID: 25660762
[TBL] [Abstract][Full Text] [Related]
12. 8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.
Funke M; Thimm D; Schiedel AC; Müller CE
J Med Chem; 2013 Jun; 56(12):5182-97. PubMed ID: 23713606
[TBL] [Abstract][Full Text] [Related]
13. Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.
Rosethorne EM; Charlton SJ
Mol Pharmacol; 2011 Apr; 79(4):749-57. PubMed ID: 21134907
[TBL] [Abstract][Full Text] [Related]
14. The antiallergic mast cell stabilizers lodoxamide and bufrolin as the first high and equipotent agonists of human and rat GPR35.
MacKenzie AE; Caltabiano G; Kent TC; Jenkins L; McCallum JE; Hudson BD; Nicklin SA; Fawcett L; Markwick R; Charlton SJ; Milligan G
Mol Pharmacol; 2014 Jan; 85(1):91-104. PubMed ID: 24113750
[TBL] [Abstract][Full Text] [Related]
15. Thieno[3,2-b]thiophene-2-carboxylic acid derivatives as GPR35 agonists.
Deng H; Hu J; Hu H; He M; Fang Y
Bioorg Med Chem Lett; 2012 Jun; 22(12):4148-52. PubMed ID: 22572579
[TBL] [Abstract][Full Text] [Related]
16. A Systematic Approach to Identify Biased Agonists of the Apelin Receptor through High-Throughput Screening.
McAnally D; Siddiquee K; Sharir H; Qi F; Phatak S; Li JL; Berg E; Fishman J; Smith L
SLAS Discov; 2017 Aug; 22(7):867-878. PubMed ID: 28314120
[TBL] [Abstract][Full Text] [Related]
17. Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors.
Azzi M; Charest PG; Angers S; Rousseau G; Kohout T; Bouvier M; Piñeyro G
Proc Natl Acad Sci U S A; 2003 Sep; 100(20):11406-11. PubMed ID: 13679574
[TBL] [Abstract][Full Text] [Related]
18. A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine.
DeWire SM; Yamashita DS; Rominger DH; Liu G; Cowan CL; Graczyk TM; Chen XT; Pitis PM; Gotchev D; Yuan C; Koblish M; Lark MW; Violin JD
J Pharmacol Exp Ther; 2013 Mar; 344(3):708-17. PubMed ID: 23300227
[TBL] [Abstract][Full Text] [Related]
19. Activation of the Orphan G Protein-Coupled Receptor GPR27 by Surrogate Ligands Promotes
Dupuis N; Laschet C; Franssen D; Szpakowska M; Gilissen J; Geubelle P; Soni A; Parent AS; Pirotte B; Chevigné A; Twizere JC; Hanson J
Mol Pharmacol; 2017 Jun; 91(6):595-608. PubMed ID: 28314853
[TBL] [Abstract][Full Text] [Related]
20. β-Arrestin 2 dependence of δ opioid receptor agonists is correlated with alcohol intake.
Chiang T; Sansuk K; van Rijn RM
Br J Pharmacol; 2016 Jan; 173(2):332-43. PubMed ID: 26507558
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
