These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

664 related articles for article (PubMed ID: 23263183)

  • 1. Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
    Efeyan A; Zoncu R; Chang S; Gumper I; Snitkin H; Wolfson RL; Kirak O; Sabatini DD; Sabatini DM
    Nature; 2013 Jan; 493(7434):679-83. PubMed ID: 23263183
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.
    Peng M; Yin N; Li MO
    Cell; 2014 Sep; 159(1):122-133. PubMed ID: 25259925
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.
    Bar-Peled L; Schweitzer LD; Zoncu R; Sabatini DM
    Cell; 2012 Sep; 150(6):1196-208. PubMed ID: 22980980
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
    Jin G; Lee SW; Zhang X; Cai Z; Gao Y; Chou PC; Rezaeian AH; Han F; Wang CY; Yao JC; Gong Z; Chan CH; Huang CY; Tsai FJ; Tsai CH; Tu SH; Wu CH; Sarbassov dos D; Ho YS; Lin HK
    Mol Cell; 2015 Jun; 58(6):989-1000. PubMed ID: 26051179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
    Tsun ZY; Bar-Peled L; Chantranupong L; Zoncu R; Wang T; Kim C; Spooner E; Sabatini DM
    Mol Cell; 2013 Nov; 52(4):495-505. PubMed ID: 24095279
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells.
    Kalaitzidis D; Lee D; Efeyan A; Kfoury Y; Nayyar N; Sykes DB; Mercier FE; Papazian A; Baryawno N; Victora GD; Neuberg D; Sabatini DM; Scadden DT
    J Clin Invest; 2017 Apr; 127(4):1405-1413. PubMed ID: 28319048
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rag GTPases are cardioprotective by regulating lysosomal function.
    Kim YC; Park HW; Sciarretta S; Mo JS; Jewell JL; Russell RC; Wu X; Sadoshima J; Guan KL
    Nat Commun; 2014 Jul; 5():4241. PubMed ID: 24980141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sestrins inhibit mTORC1 kinase activation through the GATOR complex.
    Parmigiani A; Nourbakhsh A; Ding B; Wang W; Kim YC; Akopiants K; Guan KL; Karin M; Budanov AV
    Cell Rep; 2014 Nov; 9(4):1281-91. PubMed ID: 25457612
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.
    Chantranupong L; Wolfson RL; Orozco JM; Saxton RA; Scaria SM; Bar-Peled L; Spooner E; Isasa M; Gygi SP; Sabatini DM
    Cell Rep; 2014 Oct; 9(1):1-8. PubMed ID: 25263562
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nutrients and growth factors in mTORC1 activation.
    Efeyan A; Sabatini DM
    Biochem Soc Trans; 2013 Aug; 41(4):902-5. PubMed ID: 23863153
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rag GTPase in amino acid signaling.
    Kim J; Kim E
    Amino Acids; 2016 Apr; 48(4):915-928. PubMed ID: 26781224
    [TBL] [Abstract][Full Text] [Related]  

  • 13. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1.
    Wolfson RL; Chantranupong L; Wyant GA; Gu X; Orozco JM; Shen K; Condon KJ; Petri S; Kedir J; Scaria SM; Abu-Remaileh M; Frankel WN; Sabatini DM
    Nature; 2017 Mar; 543(7645):438-442. PubMed ID: 28199306
    [TBL] [Abstract][Full Text] [Related]  

  • 14. SZT2 dictates GATOR control of mTORC1 signalling.
    Peng M; Yin N; Li MO
    Nature; 2017 Mar; 543(7645):433-437. PubMed ID: 28199315
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A multiprotein complex negatively regulates RAG GTPases and mTORC1.
    Cancer Discov; 2013 Jul; 3(7):OF24. PubMed ID: 23847368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation.
    Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P
    Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Amino acid regulation of TOR complex 1.
    Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
    Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9.
    Jung J; Genau HM; Behrends C
    Mol Cell Biol; 2015 Jul; 35(14):2479-94. PubMed ID: 25963655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids.
    Egri SB; Shen K
    J Biol Chem; 2021 Jul; 297(1):100861. PubMed ID: 34116056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RagA, but not RagB, is essential for embryonic development and adult mice.
    Efeyan A; Schweitzer LD; Bilate AM; Chang S; Kirak O; Lamming DW; Sabatini DM
    Dev Cell; 2014 May; 29(3):321-9. PubMed ID: 24768164
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.