BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

216 related articles for article (PubMed ID: 23266887)

  • 1. Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b.
    Zhang Q; Qi S; Xu M; Yu L; Tao Y; Deng Z; Wu W; Li J; Chen Z; Wong J
    Cell Res; 2013 Feb; 23(2):225-41. PubMed ID: 23266887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Human LSD2/KDM1b/AOF1 regulates gene transcription by modulating intragenic H3K4me2 methylation.
    Fang R; Barbera AJ; Xu Y; Rutenberg M; Leonor T; Bi Q; Lan F; Mei P; Yuan GC; Lian C; Peng J; Cheng D; Sui G; Kaiser UB; Shi Y; Shi YG
    Mol Cell; 2010 Jul; 39(2):222-33. PubMed ID: 20670891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel mammalian flavin-dependent histone demethylase.
    Karytinos A; Forneris F; Profumo A; Ciossani G; Battaglioli E; Binda C; Mattevi A
    J Biol Chem; 2009 Jun; 284(26):17775-82. PubMed ID: 19407342
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation.
    Fang R; Chen F; Dong Z; Hu D; Barbera AJ; Clark EA; Fang J; Yang Y; Mei P; Rutenberg M; Li Z; Zhang Y; Xu Y; Yang H; Wang P; Simon MD; Zhou Q; Li J; Marynick MP; Li X; Lu H; Kaiser UB; Kingston RE; Xu Y; Shi YG
    Mol Cell; 2013 Feb; 49(3):558-70. PubMed ID: 23260659
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide.
    Kakizawa T; Mizukami T; Itoh Y; Hasegawa M; Sasaki R; Suzuki T
    Bioorg Med Chem Lett; 2016 Feb; 26(4):1193-5. PubMed ID: 26794039
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AOF1 is a histone H3K4 demethylase possessing demethylase activity-independent repression function.
    Yang Z; Jiang J; Stewart MD; Qi S; Yamane K; Li J; Zhang Y; Wong J
    Cell Res; 2010 Mar; 20(3):276-87. PubMed ID: 20101264
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LSD2 Is an Epigenetic Player in Multiple Types of Cancer and Beyond.
    Kim HM; Liu Z
    Biomolecules; 2024 May; 14(5):. PubMed ID: 38785960
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insight into substrate recognition by histone demethylase LSD2/KDM1b.
    Chen F; Yang H; Dong Z; Fang J; Wang P; Zhu T; Gong W; Fang R; Shi YG; Li Z; Xu Y
    Cell Res; 2013 Feb; 23(2):306-9. PubMed ID: 23357850
    [No Abstract]   [Full Text] [Related]  

  • 9. A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.
    Marabelli C; Marrocco B; Pilotto S; Chittori S; Picaud S; Marchese S; Ciossani G; Forneris F; Filippakopoulos P; Schoehn G; Rhodes D; Subramaniam S; Mattevi A
    Cell Rep; 2019 Apr; 27(2):387-399.e7. PubMed ID: 30970244
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The NPAC-LSD2 complex in nucleosome demethylation.
    Caroli J; Mattevi A
    Enzymes; 2023; 53():97-111. PubMed ID: 37748839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells.
    Katz TA; Vasilatos SN; Harrington E; Oesterreich S; Davidson NE; Huang Y
    Breast Cancer Res Treat; 2014 Jul; 146(1):99-108. PubMed ID: 24924415
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysine-specific histone demethylase 1B (LSD2/KDM1B) represses p53 expression to promote proliferation and inhibit apoptosis in colorectal cancer through LSD2-mediated H3K4me2 demethylation.
    Cai S; Wang J; Zeng W; Cheng X; Liu L; Li W
    Aging (Albany NY); 2020 Jul; 12(14):14990-15001. PubMed ID: 32726297
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
    Mino K; Nishimura S; Ninomiya S; Tujii H; Matsumori Y; Tsuchida M; Hosoi M; Koseki K; Wada S; Hasegawa M; Sasaki R; Murakami-Yamaguchi Y; Narita H; Suzuki T; Miyata N; Mizukami T
    Biosci Biotechnol Biochem; 2014; 78(6):1010-7. PubMed ID: 25036127
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of the catalytic core of Saccharomyces cerevesiae histone demethylase Rph1: insights into the substrate specificity and catalytic mechanism.
    Chang Y; Wu J; Tong XJ; Zhou JQ; Ding J
    Biochem J; 2011 Jan; 433(2):295-302. PubMed ID: 21067515
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Role of LSD1 and LSD2 in Cancers of the Gastrointestinal System: An Update.
    Malagraba G; Yarmohammadi M; Javed A; Barceló C; Rubio-Tomás T
    Biomolecules; 2022 Mar; 12(3):. PubMed ID: 35327654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone demethylase LSD2 acts as an E3 ubiquitin ligase and inhibits cancer cell growth through promoting proteasomal degradation of OGT.
    Yang Y; Yin X; Yang H; Xu Y
    Mol Cell; 2015 Apr; 58(1):47-59. PubMed ID: 25773598
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular mimicry and ligand recognition in binding and catalysis by the histone demethylase LSD1-CoREST complex.
    Baron R; Binda C; Tortorici M; McCammon JA; Mattevi A
    Structure; 2011 Feb; 19(2):212-20. PubMed ID: 21300290
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insights into histone lysine demethylation.
    Hou H; Yu H
    Curr Opin Struct Biol; 2010 Dec; 20(6):739-48. PubMed ID: 20970991
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
    Chen Y; Yang Y; Wang F; Wan K; Yamane K; Zhang Y; Lei M
    Proc Natl Acad Sci U S A; 2006 Sep; 103(38):13956-61. PubMed ID: 16956976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural insight into inhibitors of flavin adenine dinucleotide-dependent lysine demethylases.
    Niwa H; Umehara T
    Epigenetics; 2017 May; 12(5):340-352. PubMed ID: 28277979
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.