BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

348 related articles for article (PubMed ID: 23267094)

  • 1. Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice.
    Momb J; Lewandowski JP; Bryant JD; Fitch R; Surman DR; Vokes SA; Appling DR
    Proc Natl Acad Sci U S A; 2013 Jan; 110(2):549-54. PubMed ID: 23267094
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion of the neural tube defect-associated gene
    Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
    J Biol Chem; 2018 Apr; 293(16):5821-5833. PubMed ID: 29483189
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of neural tube defect-associated gene Mthfd1l causes reduced cranial mesenchyme density.
    Shin M; Vaughn A; Momb J; Appling DR
    Birth Defects Res; 2019 Nov; 111(19):1520-1534. PubMed ID: 31518072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice.
    Beaudin AE; Perry CA; Stabler SP; Allen RH; Stover PJ
    Am J Clin Nutr; 2012 Apr; 95(4):882-91. PubMed ID: 22378735
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos.
    Pike ST; Rajendra R; Artzt K; Appling DR
    J Biol Chem; 2010 Feb; 285(7):4612-20. PubMed ID: 19948730
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabotype analysis of Mthfd1l-null mouse embryos using desorption electrospray ionization mass spectrometry imaging.
    Vaughn A; DeHoog RJ; Eberlin LS; Appling DR
    Anal Bioanal Chem; 2021 May; 413(13):3573-3582. PubMed ID: 33829277
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
    Christensen KE; Hou W; Bahous RH; Deng L; Malysheva OV; Arning E; Bottiglieri T; Caudill MA; Jerome-Majewska LA; Rozen R
    Am J Clin Nutr; 2016 Nov; 104(5):1459-1469. PubMed ID: 27707701
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An NTD-associated polymorphism in the 3' UTR of MTHFD1L can affect disease risk by altering miRNA binding.
    Minguzzi S; Selcuklu SD; Spillane C; Parle-McDermott A
    Hum Mutat; 2014 Jan; 35(1):96-104. PubMed ID: 24123340
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitochondrial one-carbon metabolism and neural tube defects.
    Momb J; Appling DR
    Birth Defects Res A Clin Mol Teratol; 2014 Aug; 100(8):576-83. PubMed ID: 24985542
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development.
    Christensen KE; Deng L; Leung KY; Arning E; Bottiglieri T; Malysheva OV; Caudill MA; Krupenko NI; Greene ND; Jerome-Majewska L; MacKenzie RE; Rozen R
    Hum Mol Genet; 2013 Sep; 22(18):3705-19. PubMed ID: 23704330
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Formate Supplementation May Prevent Some Neural Tube Defects that Prove Resistant to Folic Acid: Supplementation with formate rescued normal neural tube closure in more than three quarters of the embryos of novel folic acid-resistant neural tube defect mouse models.
    Am J Med Genet A; 2018 Aug; 176(8):1697-1698. PubMed ID: 30136438
    [No Abstract]   [Full Text] [Related]  

  • 12. Association of main folate metabolic pathway gene polymorphisms with neural tube defects in Han population of Northern China.
    Fang Y; Zhang R; Zhi X; Zhao L; Cao L; Wang Y; Cai C
    Childs Nerv Syst; 2018 Apr; 34(4):725-729. PubMed ID: 29392422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mild Choline Deficiency and MTHFD1 Synthetase Deficiency Interact to Increase Incidence of Developmental Delays and Defects in Mice.
    Christensen KE; Malysheva OV; Carlin S; Matias F; MacFarlane AJ; Jacobs RL; Caudill MA; Rozen R
    Nutrients; 2021 Dec; 14(1):. PubMed ID: 35011003
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Formate supplementation enhances folate-dependent nucleotide biosynthesis and prevents spina bifida in a mouse model of folic acid-resistant neural tube defects.
    Sudiwala S; De Castro SC; Leung KY; Brosnan JT; Brosnan ME; Mills K; Copp AJ; Greene ND
    Biochimie; 2016 Jul; 126():63-70. PubMed ID: 26924399
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MTHFD1 formyltetrahydrofolate synthetase deficiency, a model for the MTHFD1 R653Q variant, leads to congenital heart defects in mice.
    Christensen KE; Deng L; Bahous RH; Jerome-Majewska LA; Rozen R
    Birth Defects Res A Clin Mol Teratol; 2015 Dec; 103(12):1031-8. PubMed ID: 26408344
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distinct effects of folate pathway genes MTHFR and MTHFD1L on ruminative response style: a potential risk mechanism for depression.
    Eszlari N; Kovacs D; Petschner P; Pap D; Gonda X; Elliott R; Anderson IM; Deakin JF; Bagdy G; Juhasz G
    Transl Psychiatry; 2016 Mar; 6(3):e745. PubMed ID: 26926881
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Optical coherence tomography-guided Brillouin microscopy highlights regional tissue stiffness differences during anterior neural tube closure in the Mthfd1l murine mutant.
    Ambekar YS; Caiaffa CD; Wlodarczyk BJ; Singh M; Schill AW; Steele JW; Zhang J; Aglyamov SR; Scarcelli G; Finnell RH; Larin KV
    Development; 2024 May; 151(10):. PubMed ID: 38682273
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Melatonin modulates metabolic remodeling in HNSCC by suppressing MTHFD1L-formate axis.
    Cui L; Zhao X; Jin Z; Wang H; Yang SF; Hu S
    J Pineal Res; 2021 Dec; 71(4):e12767. PubMed ID: 34533844
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs.
    Patel H; Pietro ED; MacKenzie RE
    J Biol Chem; 2003 May; 278(21):19436-41. PubMed ID: 12646567
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Genotyping of a tri-allelic polymorphism by a novel melting curve assay in MTHFD1L: an association study of nonsyndromic Cleft in Ireland.
    Minguzzi S; Molloy AM; Peadar K; Mills J; Scott JM; Troendle J; Pangilinan F; Brody L; Parle-McDermott A
    BMC Med Genet; 2012 Apr; 13():29. PubMed ID: 22520921
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.