BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

203 related articles for article (PubMed ID: 23270460)

  • 1. Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.
    Schmidt MR; Stansfeld PJ; Tucker SJ; Sansom MS
    Biochemistry; 2013 Jan; 52(2):279-81. PubMed ID: 23270460
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PIP(2)-binding site in Kir channels: definition by multiscale biomolecular simulations.
    Stansfeld PJ; Hopkinson R; Ashcroft FM; Sansom MS
    Biochemistry; 2009 Nov; 48(46):10926-33. PubMed ID: 19839652
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2.
    Hansen SB; Tao X; MacKinnon R
    Nature; 2011 Aug; 477(7365):495-8. PubMed ID: 21874019
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cytosolic GH loop regulates the phosphatidylinositol 4,5-bisphosphate-induced gating kinetics of Kir2 channels.
    An HL; Lü SQ; Li JW; Meng XY; Zhan Y; Cui M; Long M; Zhang HL; Logothetis DE
    J Biol Chem; 2012 Dec; 287(50):42278-87. PubMed ID: 23033482
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP
    Ha J; Xu Y; Kawano T; Hendon T; Baki L; Garai S; Papapetropoulos A; Thakur GA; Plant LD; Logothetis DE
    J Biol Chem; 2018 Mar; 293(10):3546-3561. PubMed ID: 29317494
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Energetics and location of phosphoinositide binding in human Kir2.1 channels.
    D'Avanzo N; Lee SJ; Cheng WWL; Nichols CG
    J Biol Chem; 2013 Jun; 288(23):16726-16737. PubMed ID: 23564459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate.
    D'Avanzo N; Cheng WW; Doyle DA; Nichols CG
    J Biol Chem; 2010 Nov; 285(48):37129-32. PubMed ID: 20921230
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in Nature Conferred a High Affinity Phosphatidylinositol 4,5-Bisphosphate-binding Site in Vertebrate Inwardly Rectifying Potassium Channels.
    Tang QY; Larry T; Hendra K; Yamamoto E; Bell J; Cui M; Logothetis DE; Boland LM
    J Biol Chem; 2015 Jul; 290(27):16517-29. PubMed ID: 25957411
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels.
    Zangerl-Plessl EM; Lee SJ; Maksaev G; Bernsteiner H; Ren F; Yuan P; Stary-Weinzinger A; Nichols CG
    J Gen Physiol; 2020 Jan; 152(1):. PubMed ID: 31744859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distant cytosolic residues mediate a two-way molecular switch that controls the modulation of inwardly rectifying potassium (Kir) channels by cholesterol and phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)).
    Rosenhouse-Dantsker A; Noskov S; Han H; Adney SK; Tang QY; Rodríguez-Menchaca AA; Kowalsky GB; Petrou VI; Osborn CV; Logothetis DE; Levitan I
    J Biol Chem; 2012 Nov; 287(48):40266-78. PubMed ID: 22995912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characteristic interactions with phosphatidylinositol 4,5-bisphosphate determine regulation of kir channels by diverse modulators.
    Du X; Zhang H; Lopes C; Mirshahi T; Rohacs T; Logothetis DE
    J Biol Chem; 2004 Sep; 279(36):37271-81. PubMed ID: 15155739
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Defining how multiple lipid species interact with inward rectifier potassium (Kir2) channels.
    Duncan AL; Corey RA; Sansom MSP
    Proc Natl Acad Sci U S A; 2020 Apr; 117(14):7803-7813. PubMed ID: 32213593
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids.
    Lee SJ; Ren F; Zangerl-Plessl EM; Heyman S; Stary-Weinzinger A; Yuan P; Nichols CG
    J Gen Physiol; 2016 Sep; 148(3):227-37. PubMed ID: 27527100
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity.
    Xie LH; John SA; Ribalet B; Weiss JN
    J Physiol; 2008 Apr; 586(7):1833-48. PubMed ID: 18276733
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual-mode phospholipid regulation of human inward rectifying potassium channels.
    Cheng WWL; D'Avanzo N; Doyle DA; Nichols CG
    Biophys J; 2011 Feb; 100(3):620-628. PubMed ID: 21281576
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Arachidonic acid activates Kir2.3 channels by enhancing channel-phosphatidyl-inositol 4,5-bisphosphate interactions.
    Wang C; Mirshahi UL; Liu B; Jia Z; Mirshahi T; Zhang H
    Mol Pharmacol; 2008 Apr; 73(4):1185-94. PubMed ID: 18202303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules.
    Barbera N; Ayee MAA; Akpa BS; Levitan I
    Biophys J; 2018 Oct; 115(7):1264-1280. PubMed ID: 30205899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of the PIP2-binding site on Kir6.2 by molecular modelling and functional analysis.
    Haider S; Tarasov AI; Craig TJ; Sansom MS; Ashcroft FM
    EMBO J; 2007 Aug; 26(16):3749-59. PubMed ID: 17673911
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vivo light-induced and basal phospholipase C activity in Drosophila photoreceptors measured with genetically targeted phosphatidylinositol 4,5-bisphosphate-sensitive ion channels (Kir2.1).
    Hardie RC; Gu Y; Martin F; Sweeney ST; Raghu P
    J Biol Chem; 2004 Nov; 279(46):47773-82. PubMed ID: 15355960
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism.
    Takano M; Kuratomi S
    Prog Biophys Mol Biol; 2003 Jan; 81(1):67-79. PubMed ID: 12475570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.