These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

325 related articles for article (PubMed ID: 23274896)

  • 21. Rapamycin regulates the balance between cardiomyocyte apoptosis and autophagy in chronic heart failure by inhibiting mTOR signaling.
    Gao G; Chen W; Yan M; Liu J; Luo H; Wang C; Yang P
    Int J Mol Med; 2020 Jan; 45(1):195-209. PubMed ID: 31746373
    [TBL] [Abstract][Full Text] [Related]  

  • 22. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis.
    Zhang L; Nosak C; Sollazzo P; Odisho T; Volchuk A
    BMC Cell Biol; 2014 Jul; 15():29. PubMed ID: 25011481
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.
    Hartley T; Siva M; Lai E; Teodoro T; Zhang L; Volchuk A
    BMC Cell Biol; 2010 Jul; 11():59. PubMed ID: 20659334
    [TBL] [Abstract][Full Text] [Related]  

  • 24. MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
    Yang H; Wen Y; Zhang M; Liu Q; Zhang H; Zhang J; Lu L; Ye T; Bai X; Xiao G; Wang M
    Autophagy; 2020 Feb; 16(2):271-288. PubMed ID: 31007149
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mammalian target of Rapamycin inhibition and mycobacterial survival are uncoupled in murine macrophages.
    Zullo AJ; Jurcic Smith KL; Lee S
    BMC Biochem; 2014 Feb; 15():4. PubMed ID: 24528777
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Pharmacological Inhibition of Inositol-Requiring Enzyme 1α RNase Activity Protects Pancreatic Beta Cell and Improves Diabetic Condition in Insulin Mutation-Induced Diabetes.
    Herlea-Pana O; Eeda V; Undi RB; Lim HY; Wang W
    Front Endocrinol (Lausanne); 2021; 12():749879. PubMed ID: 34675883
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Lysosomal accumulation of mTOR is enhanced by rapamycin.
    Ohsaki Y; Suzuki M; Shinohara Y; Fujimoto T
    Histochem Cell Biol; 2010 Dec; 134(6):537-44. PubMed ID: 21063721
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes.
    Xu B; Allard C; Alvarez-Mercado AI; Fuselier T; Kim JH; Coons LA; Hewitt SC; Urano F; Korach KS; Levin ER; Arvan P; Floyd ZE; Mauvais-Jarvis F
    Cell Rep; 2018 Jul; 24(1):181-196. PubMed ID: 29972779
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Biological behaviors of mutant proinsulin contribute to the phenotypic spectrum of diabetes associated with insulin gene mutations.
    Wang H; Saint-Martin C; Xu J; Ding L; Wang R; Feng W; Liu M; Shu H; Fan Z; Haataja L; Arvan P; Bellanné-Chantelot C; Cui J; Huang Y
    Mol Cell Endocrinol; 2020 Dec; 518():111025. PubMed ID: 32916194
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
    Balboa D; Saarimäki-Vire J; Borshagovski D; Survila M; Lindholm P; Galli E; Eurola S; Ustinov J; Grym H; Huopio H; Partanen J; Wartiovaara K; Otonkoski T
    Elife; 2018 Nov; 7():. PubMed ID: 30412052
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Biosynthesis, structure, and folding of the insulin precursor protein.
    Liu M; Weiss MA; Arunagiri A; Yong J; Rege N; Sun J; Haataja L; Kaufman RJ; Arvan P
    Diabetes Obes Metab; 2018 Sep; 20 Suppl 2(Suppl 2):28-50. PubMed ID: 30230185
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cells Deploy a Two-Pronged Strategy to Rectify Misfolded Proinsulin Aggregates.
    Cunningham CN; Williams JM; Knupp J; Arunagiri A; Arvan P; Tsai B
    Mol Cell; 2019 Aug; 75(3):442-456.e4. PubMed ID: 31176671
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disulfide Mispairing During Proinsulin Folding in the Endoplasmic Reticulum.
    Haataja L; Manickam N; Soliman A; Tsai B; Liu M; Arvan P
    Diabetes; 2016 Apr; 65(4):1050-60. PubMed ID: 26822090
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.
    Caramés B; Hasegawa A; Taniguchi N; Miyaki S; Blanco FJ; Lotz M
    Ann Rheum Dis; 2012 Apr; 71(4):575-81. PubMed ID: 22084394
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Molecular Pathways Leading to Induction of Cell Death and Anti-Proliferative Properties by Tacrolimus and mTOR Inhibitors in Liver Cancer Cells.
    Navarro-Villarán E; de la Cruz-Ojeda P; Contreras L; González R; Negrete M; Rodríguez-Hernández MA; Marín-Gómez LM; Álamo-Martínez JM; Calvo A; Gómez-Bravo MA; de la Cruz J; Padillo J; Muntané J
    Cell Physiol Biochem; 2020 May; 54(3):457-473. PubMed ID: 32369692
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease?
    Cai Z; Zhao B; Li K; Zhang L; Li C; Quazi SH; Tan Y
    J Neurosci Res; 2012 Jun; 90(6):1105-18. PubMed ID: 22344941
    [TBL] [Abstract][Full Text] [Related]  

  • 37. SUMOylation of Pdia3 exacerbates proinsulin misfolding and ER stress in pancreatic beta cells.
    Li N; Luo X; Yu Q; Yang P; Chen Z; Wang X; Jiang J; Xu J; Gong Q; Eizirik DL; Zhou Z; Zhao J; Xiong F; Zhang S; Wang CY
    J Mol Med (Berl); 2020 Dec; 98(12):1795-1807. PubMed ID: 33159537
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Dysregulation of autophagy in melanocytes contributes to hypopigmented macules in tuberous sclerosis complex.
    Yang F; Yang L; Wataya-Kaneda M; Hasegawa J; Yoshimori T; Tanemura A; Tsuruta D; Katayama I
    J Dermatol Sci; 2018 Feb; 89(2):155-164. PubMed ID: 29146131
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin‑mediated autophagy.
    Lin F; Liu Y; Tang L; Xu X; Zhang X; Song Y; Chen B; Ren Y; Yang X
    Mol Med Rep; 2021 Jul; 24(1):. PubMed ID: 33955513
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Proinsulin misfolding and diabetes: mutant INS gene-induced diabetes of youth.
    Liu M; Hodish I; Haataja L; Lara-Lemus R; Rajpal G; Wright J; Arvan P
    Trends Endocrinol Metab; 2010 Nov; 21(11):652-9. PubMed ID: 20724178
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.