These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 23277357)

  • 1. Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion, and metastasis.
    Northey JJ; Dong Z; Ngan E; Kaplan A; Hardy WR; Pawson T; Siegel PM
    J Biol Chem; 2013 Feb; 288(7):5210-22. PubMed ID: 23277357
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.
    Northey JJ; Chmielecki J; Ngan E; Russo C; Annis MG; Muller WJ; Siegel PM
    Mol Cell Biol; 2008 May; 28(10):3162-76. PubMed ID: 18332126
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The SHCA adapter protein cooperates with lipoma-preferred partner in the regulation of adhesion dynamics and invadopodia formation.
    Kiepas A; Voorand E; Senecal J; Ahn R; Annis MG; Jacquet K; Tali G; Bisson N; Ursini-Siegel J; Siegel PM; Brown CM
    J Biol Chem; 2020 Jul; 295(31):10535-10559. PubMed ID: 32299913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ShcA SH2 domain engages a 14-3-3/PI3'K signaling complex and promotes breast cancer cell survival.
    Ursini-Siegel J; Hardy WR; Zheng Y; Ling C; Zuo D; Zhang C; Podmore L; Pawson T; Muller WJ
    Oncogene; 2012 Nov; 31(48):5038-44. PubMed ID: 22286768
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ShcA signalling is essential for tumour progression in mouse models of human breast cancer.
    Ursini-Siegel J; Hardy WR; Zuo D; Lam SH; Sanguin-Gendreau V; Cardiff RD; Pawson T; Muller WJ
    EMBO J; 2008 Mar; 27(6):910-20. PubMed ID: 18273058
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.
    Ha JR; Ahn R; Smith HW; Sabourin V; Hébert S; Cepeda Cañedo E; Im YK; Kleinman CL; Muller WJ; Ursini-Siegel J
    Mol Cancer Res; 2018 May; 16(5):894-908. PubMed ID: 29453318
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential utilization of ShcA tyrosine residues and functional domains in the transduction of epidermal growth factor-induced mitogen-activated protein kinase activation in 293T cells and nerve growth factor-induced neurite outgrowth in PC12 cells. Identification of a new Grb2.Sos1 binding site.
    Thomas D; Bradshaw RA
    J Biol Chem; 1997 Aug; 272(35):22293-9. PubMed ID: 9268379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer.
    Dankort D; Maslikowski B; Warner N; Kanno N; Kim H; Wang Z; Moran MF; Oshima RG; Cardiff RD; Muller WJ
    Mol Cell Biol; 2001 Mar; 21(5):1540-51. PubMed ID: 11238891
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.
    Im YK; La Selva R; Gandin V; Ha JR; Sabourin V; Sonenberg N; Pawson T; Topisirovic I; Ursini-Siegel J
    Oncogene; 2015 Mar; 34(13):1729-35. PubMed ID: 24837366
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.
    Ahn R; Sabourin V; Ha JR; Cory S; Maric G; Im YK; Hardy WR; Zhao H; Park M; Hallett M; Siegel PM; Pawson T; Ursini-Siegel J
    Cancer Res; 2013 Jul; 73(14):4521-32. PubMed ID: 23695548
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
    O'Bryan JP; Songyang Z; Cantley L; Der CJ; Pawson T
    Proc Natl Acad Sci U S A; 1996 Apr; 93(7):2729-34. PubMed ID: 8610109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells.
    Audero E; Cascone I; Maniero F; Napione L; Arese M; Lanfrancone L; Bussolino F
    J Biol Chem; 2004 Mar; 279(13):13224-33. PubMed ID: 14665640
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Non-redundant role of Shc in Erk activation by cytoskeletal reorganization.
    Faisal A; Kleiner S; Nagamine Y
    J Biol Chem; 2004 Jan; 279(5):3202-11. PubMed ID: 14576154
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β).
    Lin S; Yu L; Yang J; Liu Z; Karia B; Bishop AJR; Jackson J; Lozano G; Copland JA; Mu X; Sun B; Sun LZ
    J Biol Chem; 2011 Dec; 286(51):44023-44034. PubMed ID: 22039050
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ShcA phosphotyrosine docking protein uses distinct mechanisms to regulate myocyte and global heart function.
    Vanderlaan RD; Hardy WR; Kabir MG; Pasculescu A; Jones N; deTombe PP; Backx PH; Pawson T
    Circ Res; 2011 Jan; 108(2):184-93. PubMed ID: 21148430
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.
    Ong SH; Dilworth S; Hauck-Schmalenberger I; Pawson T; Kiefer F
    EMBO J; 2001 Nov; 20(22):6327-36. PubMed ID: 11707404
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interplay between ShcA Signaling and PGC-1α Triggers Targetable Metabolic Vulnerabilities in Breast Cancer.
    Im YK; Najyb O; Gravel SP; McGuirk S; Ahn R; Avizonis DZ; Chénard V; Sabourin V; Hudson J; Pawson T; Topisirovic I; Pollak M; St-Pierre J; Ursini-Siegel J
    Cancer Res; 2018 Sep; 78(17):4826-4838. PubMed ID: 29930100
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ShcA adaptor protein is a critical regulator of breast cancer progression.
    Ursini-Siegel J; Muller WJ
    Cell Cycle; 2008 Jul; 7(13):1936-43. PubMed ID: 18604176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules.
    Nakamura T; Komiya M; Gotoh N; Koizumi S; Shibuya M; Mori N
    Oncogene; 2002 Jan; 21(1):22-31. PubMed ID: 11791173
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation.
    Muthusamy BP; Budi EH; Katsuno Y; Lee MK; Smith SM; Mirza AM; Akhurst RJ; Derynck R
    PLoS Biol; 2015 Dec; 13(12):e1002325. PubMed ID: 26680585
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.