These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 23277537)

  • 1. Identification of a hidden strain switch provides clues to an ancient structural mechanism in protein kinases.
    Oruganty K; Talathi NS; Wood ZA; Kannan N
    Proc Natl Acad Sci U S A; 2013 Jan; 110(3):924-9. PubMed ID: 23277537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evolutionary variation and adaptation in a conserved protein kinase allosteric network: implications for inhibitor design.
    Oruganty K; Kannan N
    Biochim Biophys Acta; 2013 Jul; 1834(7):1322-9. PubMed ID: 23499783
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
    Frödin M; Antal TL; Dümmler BA; Jensen CJ; Deak M; Gammeltoft S; Biondi RM
    EMBO J; 2002 Oct; 21(20):5396-407. PubMed ID: 12374740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome-wide and structural analyses of pseudokinases encoded in the genome of Arabidopsis thaliana provide functional insights.
    Paul A; Srinivasan N
    Proteins; 2020 Dec; 88(12):1620-1638. PubMed ID: 32667690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional Role of Histidine in the Conserved His-x-Asp Motif in the Catalytic Core of Protein Kinases.
    Zhang L; Wang JC; Hou L; Cao PR; Wu L; Zhang QS; Yang HY; Zang Y; Ding JP; Li J
    Sci Rep; 2015 May; 5():10115. PubMed ID: 25960268
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization.
    Mohanty S; Oruganty K; Kwon A; Byrne DP; Ferries S; Ruan Z; Hanold LE; Katiyar S; Kennedy EJ; Eyers PA; Kannan N
    PLoS Genet; 2016 Feb; 12(2):e1005885. PubMed ID: 26925779
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Allosteric activation by dimerization of the PknD receptor Ser/Thr protein kinase from Mycobacterium tuberculosis.
    Greenstein AE; Echols N; Lombana TN; King DS; Alber T
    J Biol Chem; 2007 Apr; 282(15):11427-35. PubMed ID: 17242402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mass spectrometry and site-directed mutagenesis identify several autophosphorylated residues required for the activity of PrkC, a Ser/Thr kinase from Bacillus subtilis.
    Madec E; Stensballe A; Kjellström S; Cladière L; Obuchowski M; Jensen ON; Séror SJ
    J Mol Biol; 2003 Jul; 330(3):459-72. PubMed ID: 12842463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site.
    Adams J; Chen ZP; Van Denderen BJ; Morton CJ; Parker MW; Witters LA; Stapleton D; Kemp BE
    Protein Sci; 2004 Jan; 13(1):155-65. PubMed ID: 14691231
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphoinositide-dependent kinase-1 orthologues from five eukaryotes are activated by the hydrophobic motif in AGC kinases.
    Silber J; Antal TL; Gammeltoft S; Rasmussen TE
    Biochem Biophys Res Commun; 2004 Sep; 321(4):823-7. PubMed ID: 15358101
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation.
    Kikani CK; Antonysamy SA; Bonanno JB; Romero R; Zhang FF; Russell M; Gheyi T; Iizuka M; Emtage S; Sauder JM; Turk BE; Burley SK; Rutter J
    J Biol Chem; 2010 Dec; 285(52):41034-43. PubMed ID: 20943661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A conserved Glu-Arg salt bridge connects coevolved motifs that define the eukaryotic protein kinase fold.
    Yang J; Wu J; Steichen JM; Kornev AP; Deal MS; Li S; Sankaran B; Woods VL; Taylor SS
    J Mol Biol; 2012 Jan; 415(4):666-79. PubMed ID: 22138346
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutive activation of mitogen-activated protein kinase-activated protein kinase 2 by mutation of phosphorylation sites and an A-helix motif.
    Engel K; Schultz H; Martin F; Kotlyarov A; Plath K; Hahn M; Heinemann U; Gaestel M
    J Biol Chem; 1995 Nov; 270(45):27213-21. PubMed ID: 7592979
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lining the pockets of kinases and phosphatases.
    Gold MG; Barford D; Komander D
    Curr Opin Struct Biol; 2006 Dec; 16(6):693-701. PubMed ID: 17084073
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and mechanistic insights into Mps1 kinase activation.
    Wang W; Yang Y; Gao Y; Xu Q; Wang F; Zhu S; Old W; Resing K; Ahn N; Lei M; Liu X
    J Cell Mol Med; 2009 Aug; 13(8B):1679-1694. PubMed ID: 19120698
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase.
    Wang X; Goshe MB; Soderblom EJ; Phinney BS; Kuchar JA; Li J; Asami T; Yoshida S; Huber SC; Clouse SD
    Plant Cell; 2005 Jun; 17(6):1685-703. PubMed ID: 15894717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP.
    Yang J; Cron P; Good VM; Thompson V; Hemmings BA; Barford D
    Nat Struct Biol; 2002 Dec; 9(12):940-4. PubMed ID: 12434148
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The "catalytic" triad of isocitrate dehydrogenase kinase/phosphatase from E. coli and its relationship with that found in eukaryotic protein kinases.
    Oudot C; Cortay JC; Blanchet C; Laporte DC; Di Pietro A; Cozzone AJ; Jault JM
    Biochemistry; 2001 Mar; 40(10):3047-55. PubMed ID: 11258918
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2.
    Gárriz A; Qiu H; Dey M; Seo EJ; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2009 Mar; 29(6):1592-607. PubMed ID: 19114556
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.
    Kinstrie R; Luebbering N; Miranda-Saavedra D; Sibbet G; Han J; Lochhead PA; Cleghon V
    Sci Signal; 2010 Mar; 3(111):ra16. PubMed ID: 20197545
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.