229 related articles for article (PubMed ID: 23278685)
1. Study of drug supersaturation for rational early formulation screening of surfactant/co-solvent drug delivery systems.
Stillhart C; Cavegn M; Kuentz M
J Pharm Pharmacol; 2013 Feb; 65(2):181-92. PubMed ID: 23278685
[TBL] [Abstract][Full Text] [Related]
2. In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine.
Devraj R; Williams HD; Warren DB; Mohsin K; Porter CJ; Pouton CW
Eur J Pharm Sci; 2013 Jul; 49(4):748-60. PubMed ID: 23684915
[TBL] [Abstract][Full Text] [Related]
3. Rapid determination of drug solubilization versus supersaturation in natural and digested lipids.
Gautschi N; Bergström CA; Kuentz M
Int J Pharm; 2016 Nov; 513(1-2):164-174. PubMed ID: 27609663
[TBL] [Abstract][Full Text] [Related]
4. In-vitro prediction of bioavailability following extravascular injection of poorly soluble drugs: an insight into clinical failure and the role of delivery systems.
Wu Z; Hassan D; Shaw JP
J Pharm Pharmacol; 2013 Oct; 65(10):1429-39. PubMed ID: 24028610
[TBL] [Abstract][Full Text] [Related]
5. Lipid digestion as a trigger for supersaturation: evaluation of the impact of supersaturation stabilization on the in vitro and in vivo performance of self-emulsifying drug delivery systems.
Anby MU; Williams HD; McIntosh M; Benameur H; Edwards GA; Pouton CW; Porter CJ
Mol Pharm; 2012 Jul; 9(7):2063-79. PubMed ID: 22656917
[TBL] [Abstract][Full Text] [Related]
6. Design of lipid-based formulations for oral administration of poorly water-soluble drugs: precipitation of drug after dispersion of formulations in aqueous solution.
Mohsin K; Long MA; Pouton CW
J Pharm Sci; 2009 Oct; 98(10):3582-95. PubMed ID: 19130605
[TBL] [Abstract][Full Text] [Related]
7. Toward the establishment of standardized in vitro tests for lipid-based formulations, part 4: proposing a new lipid formulation performance classification system.
Williams HD; Sassene P; Kleberg K; Calderone M; Igonin A; Jule E; Vertommen J; Blundell R; Benameur H; Müllertz A; Porter CJ; Pouton CW;
J Pharm Sci; 2014 Aug; 103(8):2441-55. PubMed ID: 24985238
[TBL] [Abstract][Full Text] [Related]
8. A win-win solution in oral delivery of lipophilic drugs: supersaturation via amorphous solid dispersions increases apparent solubility without sacrifice of intestinal membrane permeability.
Miller JM; Beig A; Carr RA; Spence JK; Dahan A
Mol Pharm; 2012 Jul; 9(7):2009-16. PubMed ID: 22632106
[TBL] [Abstract][Full Text] [Related]
9. Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623.
McEvoy CL; Trevaskis NL; Feeney OM; Edwards GA; Perlman ME; Ambler CM; Porter CJH
Mol Pharm; 2017 Dec; 14(12):4525-4538. PubMed ID: 29076741
[TBL] [Abstract][Full Text] [Related]
10. Micellar solubilization of poorly water-soluble drugs: effect of surfactant and solubilizate molecular structure.
Vinarov Z; Katev V; Radeva D; Tcholakova S; Denkov ND
Drug Dev Ind Pharm; 2018 Apr; 44(4):677-686. PubMed ID: 29164955
[TBL] [Abstract][Full Text] [Related]
11. Excipient-mediated supersaturation stabilization in human intestinal fluids.
Bevernage J; Forier T; Brouwers J; Tack J; Annaert P; Augustijns P
Mol Pharm; 2011 Apr; 8(2):564-70. PubMed ID: 21268663
[TBL] [Abstract][Full Text] [Related]
12. Choice of nonionic surfactant used to formulate type IIIA self-emulsifying drug delivery systems and the physicochemical properties of the drug have a pronounced influence on the degree of drug supersaturation that develops during in vitro digestion.
Devraj R; Williams HD; Warren DB; Porter CJ; Pouton CW
J Pharm Sci; 2014 Apr; 103(4):1050-63. PubMed ID: 24470073
[TBL] [Abstract][Full Text] [Related]
13. A Relative Permittivity Approach for Fast Drug Solubility Screening of Solvents and Excipients in Lipid-Based Delivery.
Niederquell A; Dujovny G; Probst SE; Kuentz M
J Pharm Sci; 2019 Oct; 108(10):3457-3460. PubMed ID: 31255684
[TBL] [Abstract][Full Text] [Related]
14. Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation.
Suys EJA; Chalmers DK; Pouton CW; Porter CJH
Mol Pharm; 2018 Jun; 15(6):2355-2371. PubMed ID: 29659287
[TBL] [Abstract][Full Text] [Related]
15. Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate.
Griffin BT; Kuentz M; Vertzoni M; Kostewicz ES; Fei Y; Faisal W; Stillhart C; O'Driscoll CM; Reppas C; Dressman JB
Eur J Pharm Biopharm; 2014 Apr; 86(3):427-37. PubMed ID: 24184675
[TBL] [Abstract][Full Text] [Related]
16. The quest for exceptional drug solubilization in diluted surfactant solutions and consideration of residual solid state.
Saal W; Wyttenbach N; Alsenz J; Kuentz M
Eur J Pharm Sci; 2018 Jan; 111():96-103. PubMed ID: 28943442
[TBL] [Abstract][Full Text] [Related]
17. Role of excipients in successful development of self-emulsifying/microemulsifying drug delivery system (SEDDS/SMEDDS).
Rahman MA; Hussain A; Hussain MS; Mirza MA; Iqbal Z
Drug Dev Ind Pharm; 2013 Jan; 39(1):1-19. PubMed ID: 22372916
[TBL] [Abstract][Full Text] [Related]
18. Studying the effect of lipid chain length on the precipitation of a poorly water soluble drug from self-emulsifying drug delivery system on dispersion into aqueous medium.
Prasad D; Chauhan H; Atef E
J Pharm Pharmacol; 2013 Aug; 65(8):1134-44. PubMed ID: 23837581
[TBL] [Abstract][Full Text] [Related]
19. Optimization of self nanoemulsifying drug delivery system for poorly water-soluble drug using response surface methodology.
Ren S; Mu H; Alchaer F; Chtatou A; Müllertz A
Drug Dev Ind Pharm; 2013 May; 39(5):799-806. PubMed ID: 22871082
[TBL] [Abstract][Full Text] [Related]
20. A novel nanomatrix system consisted of colloidal silica and pH-sensitive polymethylacrylate improves the oral bioavailability of fenofibrate.
Jia Z; Lin P; Xiang Y; Wang X; Wang J; Zhang X; Zhang Q
Eur J Pharm Biopharm; 2011 Sep; 79(1):126-34. PubMed ID: 21658449
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
