These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

28 related articles for article (PubMed ID: 23280575)

  • 1. Mitigation of liquid-liquid phase separation of a monoclonal antibody by mutations of negative charges on the Fab surface.
    Matsuoka T; Miyauchi R; Nagaoka N; Hasegawa J
    PLoS One; 2020; 15(10):e0240673. PubMed ID: 33125371
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In silico prediction of post-translational modifications in therapeutic antibodies.
    Vatsa S
    MAbs; 2022; 14(1):2023938. PubMed ID: 35040751
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Improvement of Biophysical Properties and Affinity of a Human Anti-L1CAM Therapeutic Antibody through Antibody Engineering Based on Computational Methods.
    Chae H; Cho S; Jeong M; Kwon K; Choi D; Lee J; Nam W; Hong J; Lee J; Yoon S; Hong H
    Int J Mol Sci; 2021 Jun; 22(13):. PubMed ID: 34206616
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy.
    Hinterholzer A; Stanojlovic V; Regl C; Huber CG; Cabrele C; Schubert M
    J Biomol NMR; 2021 Jan; 75(1):71-82. PubMed ID: 33475951
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deamidation and isomerization liability analysis of 131 clinical-stage antibodies.
    Lu X; Nobrega RP; Lynaugh H; Jain T; Barlow K; Boland T; Sivasubramanian A; Vásquez M; Xu Y
    MAbs; 2019 Jan; 11(1):45-57. PubMed ID: 30526254
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differences in α-Crystallin isomerization reveal the activity of protein isoaspartyl methyltransferase (PIMT) in the nucleus and cortex of human lenses.
    Lyon YA; Sabbah GM; Julian RR
    Exp Eye Res; 2018 Jun; 171():131-141. PubMed ID: 29571628
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein engineering to increase the potential of a therapeutic antibody Fab for long-acting delivery to the eye.
    Tesar D; Luoma J; Wyatt EA; Shi C; Shatz W; Hass PE; Mathieu M; Yi L; Corn JE; Maass KF; Wang K; Dion MZ; Andersen N; Loyet KM; van Lookeren Campagne M; Rajagopal K; Dickmann L; Scheer JM; Kelley RF
    MAbs; 2017; 9(8):1297-1305. PubMed ID: 28854082
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of the interactions of critical scale-up parameters (pH, pO
    Brunner M; Fricke J; Kroll P; Herwig C
    Bioprocess Biosyst Eng; 2017 Feb; 40(2):251-263. PubMed ID: 27752770
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study.
    Takahashi O; Kirikoshi R; Manabe N
    Int J Mol Sci; 2015 Jan; 16(1):1613-26. PubMed ID: 25588215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. In silico selection of therapeutic antibodies for development: viscosity, clearance, and chemical stability.
    Sharma VK; Patapoff TW; Kabakoff B; Pai S; Hilario E; Zhang B; Li C; Borisov O; Kelley RF; Chorny I; Zhou JZ; Dill KA; Swartz TE
    Proc Natl Acad Sci U S A; 2014 Dec; 111(52):18601-6. PubMed ID: 25512516
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of intramolecular and intermolecular hydrogen bonding in a three-water-assisted mechanism of succinimide formation from aspartic acid residues.
    Takahashi O; Kirikoshi R; Manabe N
    Molecules; 2014 Aug; 19(8):11440-52. PubMed ID: 25093984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based prediction of asparagine and aspartate degradation sites in antibody variable regions.
    Sydow JF; Lipsmeier F; Larraillet V; Hilger M; Mautz B; Mølhøj M; Kuentzer J; Klostermann S; Schoch J; Voelger HR; Regula JT; Cramer P; Papadimitriou A; Kettenberger H
    PLoS One; 2014; 9(6):e100736. PubMed ID: 24959685
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of isomerization and racemization of aspartate in the Asp-Asp motifs of a therapeutic protein.
    Zhang J; Yip H; Katta V
    Anal Biochem; 2011 Mar; 410(2):234-43. PubMed ID: 21130067
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of ionic strength and pH on the physical and chemical stability of a monoclonal antibody antigen-binding fragment.
    Wang T; Kumru OS; Yi L; Wang YJ; Zhang J; Kim JH; Joshi SB; Middaugh CR; Volkin DB
    J Pharm Sci; 2013 Aug; 102(8):2520-37. PubMed ID: 23824562
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ion-pair reversed-phase high performance liquid chromatography method for the quantification of isoaspartic acid in a monoclonal antibody.
    Kern W; Mende R; Denefeld B; Sackewitz M; Chelius D
    J Chromatogr B Analyt Technol Biomed Life Sci; 2014 Apr; 955-956():26-33. PubMed ID: 24631807
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of a recombinant humanized anti-cocaine monoclonal antibody and its Fab fragment.
    Kirley TL; Norman AB
    Hum Vaccin Immunother; 2015; 11(2):458-67. PubMed ID: 25692880
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
    Fan ZC; Shan L; Goldsteen BZ; Guddat LW; Thakur A; Landolfi NF; Co MS; Vasquez M; Queen C; Ramsland PA; Edmundson AB
    J Mol Recognit; 1999; 12(1):19-32. PubMed ID: 10398393
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Isomerization of Asp-Asp motif in model peptides and a monoclonal antibody Fab fragment.
    Yi L; Beckley N; Gikanga B; Zhang J; Wang YJ; Chih HW; Sharma VK
    J Pharm Sci; 2013 Mar; 102(3):947-59. PubMed ID: 23280575
    [TBL] [Abstract][Full Text] [Related]  

  • 19.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 2.