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7. Long QT syndrome-associated mutations in KCNQ1 and KCNE1 subunits disrupt normal endosomal recycling of IKs channels. Seebohm G; Strutz-Seebohm N; Ureche ON; Henrion U; Baltaev R; Mack AF; Korniychuk G; Steinke K; Tapken D; Pfeufer A; Kääb S; Bucci C; Attali B; Merot J; Tavare JM; Hoppe UC; Sanguinetti MC; Lang F Circ Res; 2008 Dec; 103(12):1451-7. PubMed ID: 19008479 [TBL] [Abstract][Full Text] [Related]
8. Slow delayed rectifier potassium current blockade contributes importantly to drug-induced long QT syndrome. Veerman CC; Verkerk AO; Blom MT; Klemens CA; Langendijk PN; van Ginneken AC; Wilders R; Tan HL Circ Arrhythm Electrophysiol; 2013 Oct; 6(5):1002-9. PubMed ID: 23995305 [TBL] [Abstract][Full Text] [Related]
9. A590T mutation in KCNQ1 C-terminal helix D decreases IKs channel trafficking and function but not Yotiao interaction. Kinoshita K; Komatsu T; Nishide K; Hata Y; Hisajima N; Takahashi H; Kimoto K; Aonuma K; Tsushima E; Tabata T; Yoshida T; Mori H; Nishida K; Yamaguchi Y; Ichida F; Fukurotani K; Inoue H; Nishida N J Mol Cell Cardiol; 2014 Jul; 72():273-80. PubMed ID: 24713462 [TBL] [Abstract][Full Text] [Related]
10. The residue I257 at S4-S5 linker in KCNQ1 determines KCNQ1/KCNE1 channel sensitivity to 1-alkanols. Xie C; Liu HW; Pan N; Ding JP; Yao J Acta Pharmacol Sin; 2016 Jan; 37(1):124-33. PubMed ID: 26725740 [TBL] [Abstract][Full Text] [Related]
11. Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunit. Mikuni I; Torres CG; Bienengraeber MW; Kwok WM Biochim Biophys Acta; 2011 Dec; 1810(12):1285-93. PubMed ID: 21854832 [TBL] [Abstract][Full Text] [Related]
12. Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits. Chen J; Liu Z; Creagh J; Zheng R; McDonald TV Am J Physiol Heart Circ Physiol; 2020 Feb; 318(2):H212-H222. PubMed ID: 31834838 [TBL] [Abstract][Full Text] [Related]
13. Mutation of colocalized residues of the pore helix and transmembrane segments S5 and S6 disrupt deactivation and modify inactivation of KCNQ1 K+ channels. Seebohm G; Westenskow P; Lang F; Sanguinetti MC J Physiol; 2005 Mar; 563(Pt 2):359-68. PubMed ID: 15649981 [TBL] [Abstract][Full Text] [Related]
14. Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂. Dvir M; Strulovich R; Sachyani D; Ben-Tal Cohen I; Haitin Y; Dessauer C; Pongs O; Kass R; Hirsch JA; Attali B J Cell Sci; 2014 Sep; 127(Pt 18):3943-55. PubMed ID: 25037568 [TBL] [Abstract][Full Text] [Related]
16. Calmodulin is essential for cardiac IKS channel gating and assembly: impaired function in long-QT mutations. Shamgar L; Ma L; Schmitt N; Haitin Y; Peretz A; Wiener R; Hirsch J; Pongs O; Attali B Circ Res; 2006 Apr; 98(8):1055-63. PubMed ID: 16556865 [TBL] [Abstract][Full Text] [Related]
17. A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome. Moreno C; Oliveras A; de la Cruz A; Bartolucci C; Muñoz C; Salar E; Gimeno JR; Severi S; Comes N; Felipe A; González T; Lambiase P; Valenzuela C Cardiovasc Res; 2015 Sep; 107(4):613-23. PubMed ID: 26168993 [TBL] [Abstract][Full Text] [Related]
18. Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability. Aidery P; Kisselbach J; Schweizer PA; Becker R; Katus HA; Thomas D Biochim Biophys Acta; 2011 Apr; 1812(4):488-94. PubMed ID: 21241800 [TBL] [Abstract][Full Text] [Related]
19. Characterization of an LQT5-related mutation in KCNE1, Y81C: implications for a role of KCNE1 cytoplasmic domain in IKs channel function. Wu DM; Lai LP; Zhang M; Wang HL; Jiang M; Liu XS; Tseng GN Heart Rhythm; 2006 Sep; 3(9):1031-40. PubMed ID: 16945797 [TBL] [Abstract][Full Text] [Related]