112 related articles for article (PubMed ID: 2329552)
1. Hypoxia-selective antitumor agents. 4. Relationships between structure, physicochemical properties, and hypoxia-selective cytotoxicity for nitracrine analogues with varying side chains: the "iminoacridan hypothesis".
Denny WA; Atwell GJ; Anderson RF; Wilson WR
J Med Chem; 1990 May; 33(5):1288-95. PubMed ID: 2329552
[TBL] [Abstract][Full Text] [Related]
2. NMR studies of configuration and tautomeric equilibria in nitroacridine antitumor agents.
Boyd M; Denny WA
J Med Chem; 1990 Sep; 33(9):2656-9. PubMed ID: 2391704
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia-selective antitumor agents. 13. Effects of acridine substitution on the hypoxia-selective cytotoxicity and metabolic reduction of the bis-bioreductive agent nitracrine N-oxide.
Lee HH; Wilson WR; Ferry DM; van Zijl P; Pullen SM; Denny WA
J Med Chem; 1996 Jun; 39(13):2508-17. PubMed ID: 8691448
[TBL] [Abstract][Full Text] [Related]
4. Hypoxia-selective antitumor agents. 1. Relationships between structure, redox properties and hypoxia-selective cytotoxicity for 4-substituted derivatives of nitracrine.
Wilson WR; Anderson RF; Denny WA
J Med Chem; 1989 Jan; 32(1):23-30. PubMed ID: 2909736
[TBL] [Abstract][Full Text] [Related]
5. Nitracrine N-oxides: effects of variations in the nature of the side chain N-oxide on hypoxia-selective cytotoxicity.
Lee HH; Wilson WR; Denny WA
Anticancer Drug Des; 1999 Dec; 14(6):487-97. PubMed ID: 10834270
[TBL] [Abstract][Full Text] [Related]
6. Hypoxia-selective antitumor agents. 2. Electronic effects of 4-substituents on the mechanisms of cytotoxicity and metabolic stability of nitracrine derivatives.
Wilson WR; Thompson LH; Anderson RF; Denny WA
J Med Chem; 1989 Jan; 32(1):31-8. PubMed ID: 2909741
[TBL] [Abstract][Full Text] [Related]
7. Anaerobic incubation and mutagenicity of nitracrine analogues in Salmonella typhimurium.
Ferguson LR; Roberton AM; Turner PM
Mutagenesis; 1987 Jul; 2(4):253-7. PubMed ID: 3325754
[TBL] [Abstract][Full Text] [Related]
8. Selective toxicity of nitracrine to hypoxic mammalian cells.
Wilson WR; Denny WA; Twigden SJ; Baguley BC; Probert JC
Br J Cancer; 1984 Feb; 49(2):215-23. PubMed ID: 6696822
[TBL] [Abstract][Full Text] [Related]
9. Mutagenic and clastogenic activity of nitracrine analogues in cultured V79 Chinese hamster cells.
Ferguson LR; van Zijl P
Mutat Res; 1988 Apr; 204(4):655-63. PubMed ID: 3352647
[TBL] [Abstract][Full Text] [Related]
10. Bis-bioreductive agents as hypoxia-selective cytotoxins: nitracrine N-oxide.
Wilson WR; Van Zijl P; Denny WA
Int J Radiat Oncol Biol Phys; 1992; 22(4):693-6. PubMed ID: 1544839
[TBL] [Abstract][Full Text] [Related]
11. QSAR of acridines. II. Features of nitracrine analogs for high anti-tumor activity and selectivity on mice, searched by PCA and MRA methods.
Mazerska Z; Mazerski J; Ledóchowski A
Anticancer Drug Des; 1990 May; 5(2):169-87. PubMed ID: 2357263
[TBL] [Abstract][Full Text] [Related]
12. Hypoxia-selective antitumor agents. 14. Synthesis and hypoxic cell cytotoxicity of regioisomers of the hypoxia-selective cytotoxin 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
Palmer BD; Wilson WR; Anderson RF; Boyd M; Denny WA
J Med Chem; 1996 Jun; 39(13):2518-28. PubMed ID: 8691449
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia-selective antitumor agents. 10. bis(nitroimidazoles) and related Bis(nitroheterocycles): development of derivatives with higher rates of metabolic activation under hypoxia and improved aqueous solubility.
Hay MP; Lee HH; Wilson WR; Roberts PB; Denny WA
J Med Chem; 1995 May; 38(11):1928-41. PubMed ID: 7783125
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia-selective antitumor agents. 5. Synthesis of water-soluble nitroaniline mustards with selective cytotoxicity for hypoxic mammalian cells.
Palmer BD; Wilson WR; Cliffe S; Denny WA
J Med Chem; 1992 Aug; 35(17):3214-22. PubMed ID: 1507207
[TBL] [Abstract][Full Text] [Related]
15. 32P-post-labeling analysis of DNA adduct formation by antitumor drug nitracrine (Ledakrin) and other nitroacridines in different biological systems.
Bartoszek A; Konopa J
Biochem Pharmacol; 1989 Apr; 38(8):1301-12. PubMed ID: 2706021
[TBL] [Abstract][Full Text] [Related]
16. Hypoxia-selective antitumor agents. 8. Bis(nitroimidazolyl)alkanecarboxamides: a new class of hypoxia-selective cytotoxins and hypoxic cell radiosensitisers.
Hay MP; Wilson WR; Moselen JW; Palmer BD; Denny WA
J Med Chem; 1994 Feb; 37(3):381-91. PubMed ID: 8308864
[TBL] [Abstract][Full Text] [Related]
17. Antitumor activity of 1-nitro-9-aminoacridines including nitracrine against some ascitic experimental tumors.
Mazerska Z; Lukowicz J; Konopa J
Arzneimittelforschung; 1990 Apr; 40(4):472-7. PubMed ID: 2357249
[TBL] [Abstract][Full Text] [Related]
18. Hypoxia-selective antitumor agents. 9. Structure-activity relationships for hypoxia-selective cytotoxicity among analogues of 5-[N,N-bis(2-chloroethyl)amino]-2,4-dinitrobenzamide.
Palmer BD; Wilson WR; Atwell GJ; Schultz D; Xu XZ; Denny WA
J Med Chem; 1994 Jul; 37(14):2175-84. PubMed ID: 8035424
[TBL] [Abstract][Full Text] [Related]
19. Hypoxia-selective antitumor agents. 12. Nitrobenzyl quaternary salts as bioreductive prodrugs of the alkylating agent mechlorethamine.
Tercel M; Wilson WR; Anderson RF; Denny WA
J Med Chem; 1996 Mar; 39(5):1084-94. PubMed ID: 8676343
[TBL] [Abstract][Full Text] [Related]
20. Hypoxia-selective antitumor agents. 6. 4-(Alkylamino)nitroquinolines: a new class of hypoxia-selective cytotoxins.
Denny WA; Atwell GJ; Roberts PB; Anderson RF; Boyd M; Lock CJ; Wilson WR
J Med Chem; 1992 Dec; 35(26):4832-41. PubMed ID: 1479583
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]