BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 23299247)

  • 1. CYP450 1A2 and multiple UGT1A isoforms are responsible for jatrorrhizine metabolism in human liver microsomes.
    Zhou H; Shi R; Ma B; Ma Y; Wang C; Wu D; Wang X; Cheng N
    Biopharm Drug Dispos; 2013 Apr; 34(3):176-85. PubMed ID: 23299247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pharmacokinetics and metabolism of jatrorrhizine, a gastric prokinetic drug candidate.
    Shi R; Zhou H; Ma B; Ma Y; Wu D; Wang X; Luo H; Cheng N
    Biopharm Drug Dispos; 2012 Apr; 33(3):135-45. PubMed ID: 22344858
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro metabolism of jaceosidin and characterization of cytochrome P450 and UDP-glucuronosyltransferase enzymes in human liver microsomes.
    Song WY; Ji HY; Baek NI; Jeong TS; Lee HS
    Arch Pharm Res; 2010 Dec; 33(12):1985-96. PubMed ID: 21191764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro metabolism of eupatilin by multiple cytochrome P450 and UDP-glucuronosyltransferase enzymes.
    Lee HS; Ji HY; Park EJ; Kim SY
    Xenobiotica; 2007 Aug; 37(8):803-17. PubMed ID: 17701830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of N-glucuronidation of 4-(5-pyridin-4-yl-1H-[1,2,4]triazol-3-yl) pyridine-2-carbonitrile (FYX-051): a new xanthine oxidoreductase inhibitor.
    Omura K; Nakazawa T; Sato T; Iwanaga T; Nagata O
    Drug Metab Dispos; 2007 Dec; 35(12):2143-8. PubMed ID: 17761779
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Product inhibition of UDP-glucuronosyltransferase (UGT) enzymes by UDP obfuscates the inhibitory effects of UGT substrates.
    Fujiwara R; Nakajima M; Yamanaka H; Katoh M; Yokoi T
    Drug Metab Dispos; 2008 Feb; 36(2):361-7. PubMed ID: 17998297
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H; Kume T
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of cytochrome P450 and UDP-glucuronosyltransferases in metabolic pathway of homoegonol in human liver microsomes.
    Kwon SS; Kim JH; Jeong HU; Ahn KS; Oh SR; Lee HS
    Drug Metab Pharmacokinet; 2015 Aug; 30(4):305-13. PubMed ID: 26163112
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of UDP-glucuronosyltransferase isoforms responsible for leonurine glucuronidation in human liver and intestinal microsomes.
    Tan B; Cai W; Zhang J; Zhou N; Ma G; Yang P; Zhu Q; Zhu Y
    Xenobiotica; 2014 Sep; 44(9):775-84. PubMed ID: 24635759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Mano Y; Usui T; Kamimura H
    Drug Metab Dispos; 2007 Nov; 35(11):2040-4. PubMed ID: 17670842
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T; Yajima K; Suzuki K; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
    Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.
    Li T; Zheng Y; Fu F; Ji H; Chen X; Zhao Y; Zhao D; Li N; Zhang L
    Xenobiotica; 2011 Jul; 41(7):530-7. PubMed ID: 21524190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L; Sun J; Peng Y; Zhang R; Shao F; Hu X; Zhu J; Wang X; Cheng X; Zhu Y; Wan P; Feng D; Wu H; Wang G
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glucuronidation of thyroxine in human liver, jejunum, and kidney microsomes.
    Yamanaka H; Nakajima M; Katoh M; Yokoi T
    Drug Metab Dispos; 2007 Sep; 35(9):1642-8. PubMed ID: 17591679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of chamaechromone in vitro with human liver microsomes and recombinant human drug-metabolizing enzymes.
    Lou Y; Hu H; Qiu Y; Zheng J; Wang L; Zhang X; Zeng S
    Planta Med; 2014 Apr; 80(6):493-7. PubMed ID: 24687737
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucuronidation of the broad-spectrum antiviral drug arbidol by UGT isoforms.
    Song JH; Fang ZZ; Zhu LL; Cao YF; Hu CM; Ge GB; Zhao DW
    J Pharm Pharmacol; 2013 Apr; 65(4):521-7. PubMed ID: 23488780
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans.
    Kato Y; Ikushiro S; Emi Y; Tamaki S; Suzuki H; Sakaki T; Yamada S; Degawa M
    Drug Metab Dispos; 2008 Jan; 36(1):51-5. PubMed ID: 17908920
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.
    Zhu L; Ge G; Zhang H; Liu H; He G; Liang S; Zhang Y; Fang Z; Dong P; Finel M; Yang L
    Drug Metab Dispos; 2012 Mar; 40(3):529-38. PubMed ID: 22180045
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of enzymes responsible for the N-oxidation of darexaban glucuronide, the pharmacologically active metabolite of darexaban, and the glucuronidation of darexaban N-oxides in human liver microsomes.
    Shiraga T; Yajima K; Teragaki T; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
    Biol Pharm Bull; 2012; 35(3):413-21. PubMed ID: 22382330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. UDP-glucuronosyltransferase 1A6 is the major isozyme responsible for protocatechuic aldehyde glucuronidation in human liver microsomes.
    Liu HX; Liu Y; Zhang JW; Li W; Liu HT; Yang L
    Drug Metab Dispos; 2008 Aug; 36(8):1562-9. PubMed ID: 18474676
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.