236 related articles for article (PubMed ID: 23301156)
1. Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.
Realini N; Solorzano C; Pagliuca C; Pizzirani D; Armirotti A; Luciani R; Costi MP; Bandiera T; Piomelli D
Sci Rep; 2013; 3():1035. PubMed ID: 23301156
[TBL] [Abstract][Full Text] [Related]
2. Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
Dementiev A; Joachimiak A; Nguyen H; Gorelik A; Illes K; Shabani S; Gelsomino M; Ahn EE; Nagar B; Doan N
J Med Chem; 2019 Jan; 62(2):987-992. PubMed ID: 30525581
[TBL] [Abstract][Full Text] [Related]
3. Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells.
Ortega JA; Arencibia JM; La Sala G; Borgogno M; Bauer I; Bono L; Braccia C; Armirotti A; Girotto S; Ganesan A; De Vivo M
J Med Chem; 2017 Jul; 60(13):5800-5815. PubMed ID: 28603987
[TBL] [Abstract][Full Text] [Related]
4. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
[TBL] [Abstract][Full Text] [Related]
5. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).
Pizzirani D; Pagliuca C; Realini N; Branduardi D; Bottegoni G; Mor M; Bertozzi F; Scarpelli R; Piomelli D; Bandiera T
J Med Chem; 2013 May; 56(9):3518-30. PubMed ID: 23614460
[TBL] [Abstract][Full Text] [Related]
6. Targeting acid ceramidase sensitises head and neck cancer to cisplatin.
Roh JL; Park JY; Kim EH; Jang HJ
Eur J Cancer; 2016 Jan; 52():163-72. PubMed ID: 26687835
[TBL] [Abstract][Full Text] [Related]
7. Acid ceramidase is upregulated in AML and represents a novel therapeutic target.
Tan SF; Liu X; Fox TE; Barth BM; Sharma A; Turner SD; Awwad A; Dewey A; Doi K; Spitzer B; Shah MV; Morad SA; Desai D; Amin S; Zhu J; Liao J; Yun J; Kester M; Claxton DF; Wang HG; Cabot MC; Schuchman EH; Levine RL; Feith DJ; Loughran TP
Oncotarget; 2016 Dec; 7(50):83208-83222. PubMed ID: 27825124
[TBL] [Abstract][Full Text] [Related]
8. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
Morad SA; Messner MC; Levin JC; Abdelmageed N; Park H; Merrill AH; Cabot MC
Cancer Chemother Pharmacol; 2013 Mar; 71(3):635-45. PubMed ID: 23263160
[TBL] [Abstract][Full Text] [Related]
9. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION.
Realini N; Palese F; Pizzirani D; Pontis S; Basit A; Bach A; Ganesan A; Piomelli D
J Biol Chem; 2016 Jan; 291(5):2422-34. PubMed ID: 26553872
[TBL] [Abstract][Full Text] [Related]
10. C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
Flowers M; Fabriás G; Delgado A; Casas J; Abad JL; Cabot MC
Breast Cancer Res Treat; 2012 Jun; 133(2):447-58. PubMed ID: 21935601
[TBL] [Abstract][Full Text] [Related]
11. Acid ceramidase as a chemotherapeutic target to overcome resistance to the antitumoral effect of choline kinase α inhibition.
Ramírez de Molina A; de la Cueva A; Machado-Pinilla R; Rodriguez-Fanjul V; Gomez del Pulgar T; Cebrian A; Perona R; Lacal JC
Curr Cancer Drug Targets; 2012 Jul; 12(6):617-24. PubMed ID: 22515519
[TBL] [Abstract][Full Text] [Related]
12. Acid ceramidase upregulation in prostate cancer: role in tumor development and implications for therapy.
Liu X; Cheng JC; Turner LS; Elojeimy S; Beckham TH; Bielawska A; Keane TE; Hannun YA; Norris JS
Expert Opin Ther Targets; 2009 Dec; 13(12):1449-58. PubMed ID: 19874262
[TBL] [Abstract][Full Text] [Related]
13. High-throughput discovery of novel small-molecule inhibitors of acid Ceramidase.
Aseeri M; Abad JL; Delgado A; Fabriàs G; Triola G; Casas J
J Enzyme Inhib Med Chem; 2023 Dec; 38(1):343-348. PubMed ID: 36519337
[TBL] [Abstract][Full Text] [Related]
14. Acid ceramidase inhibition sensitizes human colon cancer cells to oxaliplatin through downregulation of transglutaminase 2 and β1 integrin/FAK-mediated signalling.
Klobučar M; Grbčić P; Pavelić SK; Jonjić N; Visentin S; Sedić M
Biochem Biophys Res Commun; 2018 Sep; 503(2):843-848. PubMed ID: 29920241
[TBL] [Abstract][Full Text] [Related]
15. Acid Ceramidase: A Novel Therapeutic Target in Cancer.
Vijayan Y; Lankadasari MB; Harikumar KB
Curr Top Med Chem; 2019; 19(17):1512-1520. PubMed ID: 30827244
[TBL] [Abstract][Full Text] [Related]
16. Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.
Bach A; Pizzirani D; Realini N; Vozella V; Russo D; Penna I; Melzig L; Scarpelli R; Piomelli D
J Med Chem; 2015 Dec; 58(23):9258-72. PubMed ID: 26560855
[TBL] [Abstract][Full Text] [Related]
17. Targeting ceramide metabolic pathway induces apoptosis in human breast cancer cell lines.
Vethakanraj HS; Babu TA; Sudarsanan GB; Duraisamy PK; Ashok Kumar S
Biochem Biophys Res Commun; 2015 Aug; 464(3):833-9. PubMed ID: 26188095
[TBL] [Abstract][Full Text] [Related]
18. Autophagy is increased in prostate cancer cells overexpressing acid ceramidase and enhances resistance to C6 ceramide.
Turner LS; Cheng JC; Beckham TH; Keane TE; Norris JS; Liu X
Prostate Cancer Prostatic Dis; 2011 Mar; 14(1):30-7. PubMed ID: 21116286
[TBL] [Abstract][Full Text] [Related]
19. Atom based 3D-QSAR studies on 2,4-dioxopyrimidine-1-carboxamide analogs: Validation of experimental inhibitory potencies towards acid ceramidase.
Bhattacherjee D; Bhabak KP
Eur J Pharm Sci; 2016 Feb; 83():8-18. PubMed ID: 26658266
[TBL] [Abstract][Full Text] [Related]
20. Identification of cystatin SA as a novel inhibitor of acid ceramidase.
Eliyahu E; Shtraizent N; He X; Chen D; Shalgi R; Schuchman EH
J Biol Chem; 2011 Oct; 286(41):35624-35633. PubMed ID: 21846728
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
