These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 23305851)

  • 21. Allosteric inhibition of the hepatitis C virus NS5B polymerase: in silico strategies for drug discovery and development.
    Barreca ML; Iraci N; Manfroni G; Cecchetti V
    Future Med Chem; 2011 Jun; 3(8):1027-55. PubMed ID: 21707403
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay.
    Stammers TA; Coulombe R; Duplessis M; Fazal G; Gagnon A; Garneau M; Goulet S; Jakalian A; LaPlante S; Rancourt J; Thavonekham B; Wernic D; Kukolj G; Beaulieu PL
    Bioorg Med Chem Lett; 2013 Dec; 23(24):6879-85. PubMed ID: 24176401
    [TBL] [Abstract][Full Text] [Related]  

  • 23. 2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase.
    Küçükgüzel I; Satılmış G; Gurukumar KR; Basu A; Tatar E; Nichols DB; Talele TT; Kaushik-Basu N
    Eur J Med Chem; 2013 Nov; 69():931-41. PubMed ID: 24161679
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Ligand-induced changes in hepatitis C virus NS5B polymerase structure.
    Rigat K; Wang Y; Hudyma TW; Ding M; Zheng X; Gentles RG; Beno BR; Gao M; Roberts SB
    Antiviral Res; 2010 Nov; 88(2):197-206. PubMed ID: 20813137
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of substituted N-phenylbenzenesulphonamides as a novel class of non-nucleoside hepatitis C virus polymerase inhibitors.
    May MM; Brohm D; Harrenga A; Marquardt T; Riedl B; Kreuter J; Zimmermann H; Ruebsamen-Schaeff H; Urban A
    Antiviral Res; 2012 Aug; 95(2):182-91. PubMed ID: 22580131
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Discovery of a novel series of potent non-nucleoside inhibitors of hepatitis C virus NS5B.
    Schoenfeld RC; Bourdet DL; Brameld KA; Chin E; de Vicente J; Fung A; Harris SF; Lee EK; Le Pogam S; Leveque V; Li J; Lui AS; Najera I; Rajyaguru S; Sangi M; Steiner S; Talamas FX; Taygerly JP; Zhao J
    J Med Chem; 2013 Oct; 56(20):8163-82. PubMed ID: 24069953
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase.
    Zheng BZ; D'Andrea SV; Hanumegowda U; Knipe JO; Mosure K; Zhuo X; Lemm JA; Liu M; Rigat KL; Wang YK; Fang H; Poronsky C; Cutrone J; Wu DR; Arunachalam PN; Balapragalathan TJ; Arumugam A; Mathur A; Meanwell NA; Gao M; Roberts SB; Kadow JF
    Bioorg Med Chem Lett; 2017 Aug; 27(15):3294-3300. PubMed ID: 28633899
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors.
    Canales E; Carlson JS; Appleby T; Fenaux M; Lee J; Tian Y; Tirunagari N; Wong M; Watkins WJ
    Bioorg Med Chem Lett; 2012 Jul; 22(13):4288-92. PubMed ID: 22664130
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of anthranilic acid derivatives as a novel class of allosteric inhibitors of hepatitis C NS5B polymerase.
    Nittoli T; Curran K; Insaf S; DiGrandi M; Orlowski M; Chopra R; Agarwal A; Howe AY; Prashad A; Floyd MB; Johnson B; Sutherland A; Wheless K; Feld B; O'Connell J; Mansour TS; Bloom J
    J Med Chem; 2007 May; 50(9):2108-16. PubMed ID: 17402724
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.
    Pacini B; Avolio S; Ercolani C; Koch U; Migliaccio G; Narjes F; Pacini L; Tomei L; Harper S
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6245-9. PubMed ID: 19800789
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-based virtual screening, synthesis and SAR of novel inhibitors of hepatitis C virus NS5B polymerase.
    Talele TT; Arora P; Kulkarni SS; Patel MR; Singh S; Chudayeu M; Kaushik-Basu N
    Bioorg Med Chem; 2010 Jul; 18(13):4630-8. PubMed ID: 20627595
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biochemical study of the comparative inhibition of hepatitis C virus RNA polymerase by VX-222 and filibuvir.
    Yi G; Deval J; Fan B; Cai H; Soulard C; Ranjith-Kumar CT; Smith DB; Blatt L; Beigelman L; Kao CC
    Antimicrob Agents Chemother; 2012 Feb; 56(2):830-7. PubMed ID: 22143520
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
    Jin G; Lee S; Choi M; Son S; Kim GW; Oh JW; Lee C; Lee K
    Eur J Med Chem; 2014 Mar; 75():413-25. PubMed ID: 24561671
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.
    Paparin JL; Amador A; Badaroux E; Bot S; Caillet C; Convard T; Da Costa D; Dukhan D; Griffe L; Griffon JF; LaColla M; Leroy F; Liuzzi M; Giulia Loi A; McCarville J; Mascia V; Milhau J; Onidi L; Pierra C; Rahali R; Rosinosky E; Sais E; Seifer M; Surleraux D; Standring D; Dousson CB
    Bioorg Med Chem Lett; 2017 Jun; 27(11):2634-2640. PubMed ID: 28416131
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase.
    Sofia MJ; Chang W; Furman PA; Mosley RT; Ross BS
    J Med Chem; 2012 Mar; 55(6):2481-531. PubMed ID: 22185586
    [No Abstract]   [Full Text] [Related]  

  • 36. Non-nucleoside inhibitors of HCV NS5B polymerase. Part 1: Synthetic and computational exploration of the binding modes of benzothiadiazine and 1,4-benzothiazine HCV NS5b polymerase inhibitors.
    Hendricks RT; Fell JB; Blake JF; Fischer JP; Robinson JE; Spencer SR; Stengel PJ; Bernacki AL; Leveque VJ; Le Pogam S; Rajyaguru S; Najera I; Josey JA; Harris JR; Swallow S
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3637-41. PubMed ID: 19447623
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase.
    Manfroni G; Meschini F; Barreca ML; Leyssen P; Samuele A; Iraci N; Sabatini S; Massari S; Maga G; Neyts J; Cecchetti V
    Bioorg Med Chem; 2012 Jan; 20(2):866-76. PubMed ID: 22197397
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
    Nyanguile O; Pauwels F; Van den Broeck W; Boutton CW; Quirynen L; Ivens T; van der Helm L; Vandercruyssen G; Mostmans W; Delouvroy F; Dehertogh P; Cummings MD; Bonfanti JF; Simmen KA; Raboisson P
    Antimicrob Agents Chemother; 2008 Dec; 52(12):4420-31. PubMed ID: 18852280
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Update on different aspects of HCV variability: focus on NS5B polymerase.
    Marascio N; Torti C; Liberto M; Focà A
    BMC Infect Dis; 2014; 14 Suppl 5(Suppl 5):S1. PubMed ID: 25234810
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Anti-hepatitis C virus RdRp activity and replication of novel anilinobenzothiazole derivatives.
    Peng HK; Chen WC; Lin YT; Tseng CK; Yang SY; Tzeng CC; Lee JC; Yang SC
    Antiviral Res; 2013 Oct; 100(1):269-75. PubMed ID: 23994188
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.