150 related articles for article (PubMed ID: 23307751)
1. Structures of fluoro, amino, and thiol inhibitors bound to the [Fe4S4] protein IspH.
Span I; Wang K; Wang W; Jauch J; Eisenreich W; Bacher A; Oldfield E; Groll M
Angew Chem Int Ed Engl; 2013 Feb; 52(7):2118-21. PubMed ID: 23307751
[No Abstract] [Full Text] [Related]
2. Further Insight into Crystal Structures of Escherichia coli IspH/LytB in Complex with Two Potent Inhibitors of the MEP Pathway: A Starting Point for Rational Design of New Antimicrobials.
Borel F; Barbier E; Krasutsky S; Janthawornpong K; Chaignon P; Poulter CD; Ferrer JL; Seemann M
Chembiochem; 2017 Nov; 18(21):2137-2144. PubMed ID: 28862365
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.
Janthawornpong K; Krasutsky S; Chaignon P; Rohmer M; Poulter CD; Seemann M
J Am Chem Soc; 2013 Feb; 135(5):1816-22. PubMed ID: 23316732
[TBL] [Abstract][Full Text] [Related]
4. Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Span I; Wang K; Wang W; Zhang Y; Bacher A; Eisenreich W; Li K; Schulz C; Oldfield E; Groll M
Nat Commun; 2012; 3():1042. PubMed ID: 22948824
[TBL] [Abstract][Full Text] [Related]
5. Insights into the binding of pyridines to the iron-sulfur enzyme IspH.
Span I; Wang K; Eisenreich W; Bacher A; Zhang Y; Oldfield E; Groll M
J Am Chem Soc; 2014 Jun; 136(22):7926-32. PubMed ID: 24813236
[TBL] [Abstract][Full Text] [Related]
6. Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction.
Gräwert T; Rohdich F; Span I; Bacher A; Eisenreich W; Eppinger J; Groll M
Angew Chem Int Ed Engl; 2009; 48(31):5756-9. PubMed ID: 19569147
[No Abstract] [Full Text] [Related]
7. Inhibitors of the herbicidal target IspD: allosteric site binding.
Witschel MC; Höffken HW; Seet M; Parra L; Mietzner T; Thater F; Niggeweg R; Röhl F; Illarionov B; Rohdich F; Kaiser J; Fischer M; Bacher A; Diederich F
Angew Chem Int Ed Engl; 2011 Aug; 50(34):7931-5. PubMed ID: 21766403
[No Abstract] [Full Text] [Related]
8. IspH inhibitors kill Gram-negative bacteria and mobilize immune clearance.
Singh KS; Sharma R; Reddy PAN; Vonteddu P; Good M; Sundarrajan A; Choi H; Muthumani K; Kossenkov A; Goldman AR; Tang HY; Totrov M; Cassel J; Murphy ME; Somasundaram R; Herlyn M; Salvino JM; Dotiwala F
Nature; 2021 Jan; 589(7843):597-602. PubMed ID: 33361818
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and Biological Screening of New Lawson Derivatives as Selective Substrate-Based Inhibitors of Cytochrome bo
Elamri I; Radloff M; Hohmann KF; Nimbarte VD; Nasiri HR; Bolte M; Safarian S; Michel H; Schwalbe H
ChemMedChem; 2020 Jul; 15(14):1262-1271. PubMed ID: 32159929
[TBL] [Abstract][Full Text] [Related]
10. Hydroxamic acids as potent inhibitors of Fe(II) and Mn(II) E. coli methionine aminopeptidase: biological activities and X-ray structures of oxazole hydroxamate-EcMetAP-Mn complexes.
Huguet F; Melet A; Alves de Sousa R; Lieutaud A; Chevalier J; Maigre L; Deschamps P; Tomas A; Leulliot N; Pages JM; Artaud I
ChemMedChem; 2012 Jun; 7(6):1020-30. PubMed ID: 22489069
[TBL] [Abstract][Full Text] [Related]
11. The Fragment-Based Development of a Benzofuran Hit as a New Class of
Duncan LF; Wang G; Ilyichova OV; Scanlon MJ; Heras B; Abbott BM
Molecules; 2019 Oct; 24(20):. PubMed ID: 31635355
[TBL] [Abstract][Full Text] [Related]
12. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp.
Georgescu RE; Yurieva O; Kim SS; Kuriyan J; Kong XP; O'Donnell M
Proc Natl Acad Sci U S A; 2008 Aug; 105(32):11116-21. PubMed ID: 18678908
[TBL] [Abstract][Full Text] [Related]
13. Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis.
Span I; Gräwert T; Bacher A; Eisenreich W; Groll M
J Mol Biol; 2012 Feb; 416(1):1-9. PubMed ID: 22137895
[TBL] [Abstract][Full Text] [Related]
14. Structural insights into the catalytic mechanism of the bacterial class B phosphatase AphA belonging to the DDDD superfamily of phosphohydrolases.
Leone R; Cappelletti E; Benvenuti M; Lentini G; Thaller MC; Mangani S
J Mol Biol; 2008 Dec; 384(2):478-88. PubMed ID: 18845157
[TBL] [Abstract][Full Text] [Related]
15. IspH protein of Escherichia coli: studies on iron-sulfur cluster implementation and catalysis.
Gräwert T; Kaiser J; Zepeck F; Laupitz R; Hecht S; Amslinger S; Schramek N; Schleicher E; Weber S; Haslbeck M; Buchner J; Rieder C; Arigoni D; Bacher A; Eisenreich W; Rohdich F
J Am Chem Soc; 2004 Oct; 126(40):12847-55. PubMed ID: 15469281
[TBL] [Abstract][Full Text] [Related]
16. Effect of the inhibitor-resistant M69V substitution on the structures and populations of trans-enamine beta-lactamase intermediates.
Totir MA; Padayatti PS; Helfand MS; Carey MP; Bonomo RA; Carey PR; van den Akker F
Biochemistry; 2006 Oct; 45(39):11895-904. PubMed ID: 17002290
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2- C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens.
Bartee D; Wheadon MJ; Freel Meyers CL
J Org Chem; 2018 Sep; 83(17):9580-9591. PubMed ID: 29870251
[TBL] [Abstract][Full Text] [Related]
18. The structural basis for catalysis and substrate specificity of a rhomboid protease.
Vinothkumar KR; Strisovsky K; Andreeva A; Christova Y; Verhelst S; Freeman M
EMBO J; 2010 Nov; 29(22):3797-809. PubMed ID: 20890268
[TBL] [Abstract][Full Text] [Related]
19. Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Sung MT; Lai YT; Huang CY; Chou LY; Shih HW; Cheng WC; Wong CH; Ma C
Proc Natl Acad Sci U S A; 2009 Jun; 106(22):8824-9. PubMed ID: 19458048
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of DNA helicases with DNA-competitive inhibitors.
Dubaele S; Jahnke W; Schoepfer J; Fuchs J; Chène P
Bioorg Med Chem Lett; 2006 Feb; 16(4):923-7. PubMed ID: 16300943
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
