114 related articles for article (PubMed ID: 23318905)
1. Identification of benzofuran-3-yl(phenyl)methanones as novel SIRT1 inhibitors: binding mode, inhibitory mechanism and biological action.
Wu J; Li Y; Chen K; Jiang H; Xu MH; Liu D
Eur J Med Chem; 2013 Feb; 60():441-50. PubMed ID: 23318905
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationship and interaction studies of new SIRT1 inhibitors with the scaffold of 3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole.
Wu J; Li J; Xu MH; Liu D
Bioorg Med Chem Lett; 2014 Jul; 24(14):3050-6. PubMed ID: 24880902
[TBL] [Abstract][Full Text] [Related]
3. Identification and characterization of novel indole based small molecules as anticancer agents through SIRT1 inhibition.
Panathur N; Dalimba U; Koushik PV; Alvala M; Yogeeswari P; Sriram D; Kumar V
Eur J Med Chem; 2013 Nov; 69():125-38. PubMed ID: 24013412
[TBL] [Abstract][Full Text] [Related]
4. The 2.5 Å crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition.
Zhao X; Allison D; Condon B; Zhang F; Gheyi T; Zhang A; Ashok S; Russell M; MacEwan I; Qian Y; Jamison JA; Luz JG
J Med Chem; 2013 Feb; 56(3):963-9. PubMed ID: 23311358
[TBL] [Abstract][Full Text] [Related]
5. N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2.
Huhtiniemi T; Suuronen T; Lahtela-Kakkonen M; Bruijn T; Jääskeläinen S; Poso A; Salminen A; Leppänen J; Jarho E
Bioorg Med Chem; 2010 Aug; 18(15):5616-25. PubMed ID: 20630764
[TBL] [Abstract][Full Text] [Related]
6. Hit-to-lead optimization on aryloxybenzamide derivative virtual screening hit against SIRT.
Yagci S; Gozelle M; Kaya SG; Ozkan Y; Aksel AB; Bakar-Ates F; Dundar Y; Eren G
Bioorg Med Chem; 2021 Jan; 30():115961. PubMed ID: 33360574
[TBL] [Abstract][Full Text] [Related]
7. Ethylenediamine diacetate (EDDA) mediated synthesis of aurones under ultrasound: their evaluation as inhibitors of SIRT1.
Manjulatha K; Srinivas S; Mulakayala N; Rambabu D; Prabhakar M; Arunasree KM; Alvala M; Basaveswara Rao MV; Pal M
Bioorg Med Chem Lett; 2012 Oct; 22(19):6160-5. PubMed ID: 22929231
[TBL] [Abstract][Full Text] [Related]
8. New indole-isoxazolone derivatives: Synthesis, characterisation and in vitro SIRT1 inhibition studies.
Panathur N; Gokhale N; Dalimba U; Koushik PV; Yogeeswari P; Sriram D
Bioorg Med Chem Lett; 2015 Jul; 25(14):2768-72. PubMed ID: 26025875
[TBL] [Abstract][Full Text] [Related]
9. Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2.
Galli U; Mesenzani O; Coppo C; Sorba G; Canonico PL; Tron GC; Genazzani AA
Eur J Med Chem; 2012 Sep; 55():58-66. PubMed ID: 22835719
[TBL] [Abstract][Full Text] [Related]
10. Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2.
Manjula R; Gokhale N; Unni S; Deshmukh P; Reddyrajula R; Srinivas Bharath MM; Dalimba U; Padmanabhan B
Bioorg Chem; 2019 Nov; 92():103281. PubMed ID: 31561106
[TBL] [Abstract][Full Text] [Related]
11. Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies.
Alvala M; Bhatnagar S; Ravi A; Jeankumar VU; Manjashetty TH; Yogeeswari P; Sriram D
Bioorg Med Chem Lett; 2012 May; 22(9):3256-60. PubMed ID: 22464458
[TBL] [Abstract][Full Text] [Related]
12. Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells.
Breitenstein A; Stein S; Holy EW; Camici GG; Lohmann C; Akhmedov A; Spescha R; Elliott PJ; Westphal CH; Matter CM; Lüscher TF; Tanner FC
Cardiovasc Res; 2011 Feb; 89(2):464-72. PubMed ID: 20978007
[TBL] [Abstract][Full Text] [Related]
13. Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies.
Mellini P; Carafa V; Di Rienzo B; Rotili D; De Vita D; Cirilli R; Gallinella B; Provvisiero DP; Di Maro S; Novellino E; Altucci L; Mai A
ChemMedChem; 2012 Nov; 7(11):1905-8. PubMed ID: 24155041
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives.
Koca M; Servi S; Kirilmis C; Ahmedzade M; Kazaz C; Ozbek B; Otük G
Eur J Med Chem; 2005 Dec; 40(12):1351-8. PubMed ID: 16129517
[TBL] [Abstract][Full Text] [Related]
15. Recent advances in inhibitors of sirtuin1/2: an update and perspective.
Zhou Z; Ma T; Zhu Q; Xu Y; Zha X
Future Med Chem; 2018 Apr; 10(8):907-934. PubMed ID: 29642711
[TBL] [Abstract][Full Text] [Related]
16. p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence.
Jang SY; Kim SY; Bae YS
FEBS Lett; 2011 Nov; 585(21):3360-6. PubMed ID: 21968188
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of SIRT1 by a small molecule induces apoptosis in breast cancer cells.
Kalle AM; Mallika A; Badiger J; Alinakhi ; Talukdar P; Sachchidanand
Biochem Biophys Res Commun; 2010 Oct; 401(1):13-9. PubMed ID: 20813094
[TBL] [Abstract][Full Text] [Related]
18. Bivalent SIRT1 inhibitors.
Wang J; Zang W; Liu J; Zheng W
Bioorg Med Chem Lett; 2017 Jan; 27(2):180-186. PubMed ID: 27964881
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and structure-activity relationship studies of novel sirtuin 2 (SIRT2) inhibitors with a benzamide skeleton.
Sakai T; Matsumoto Y; Ishikawa M; Sugita K; Hashimoto Y; Wakai N; Kitao A; Morishita E; Toyoshima C; Hayashi T; Akiyama T
Bioorg Med Chem; 2015 Jan; 23(2):328-39. PubMed ID: 25515955
[TBL] [Abstract][Full Text] [Related]
20. Novel 3-arylideneindolin-2-ones as inhibitors of NAD+ -dependent histone deacetylases (sirtuins).
Huber K; Schemies J; Uciechowska U; Wagner JM; Rumpf T; Lewrick F; Süss R; Sippl W; Jung M; Bracher F
J Med Chem; 2010 Feb; 53(3):1383-6. PubMed ID: 20030343
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
