574 related articles for article (PubMed ID: 23318954)
1. Fuzzy complex formation between the intrinsically disordered prothymosin α and the Kelch domain of Keap1 involved in the oxidative stress response.
Khan H; Cino EA; Brickenden A; Fan J; Yang D; Choy WY
J Mol Biol; 2013 Mar; 425(6):1011-27. PubMed ID: 23318954
[TBL] [Abstract][Full Text] [Related]
2. Microsecond molecular dynamics simulations of intrinsically disordered proteins involved in the oxidative stress response.
Cino EA; Wong-ekkabut J; Karttunen M; Choy WY
PLoS One; 2011; 6(11):e27371. PubMed ID: 22125611
[TBL] [Abstract][Full Text] [Related]
3. [Prothyomosin alpha interaction with KEAP1 doesn't lead to prothymosin alpha ubiquination and degradation].
Mel'nikov SV; Evstaf'eva AG; Vartapetian AB
Mol Biol (Mosk); 2007; 41(5):868-75. PubMed ID: 18240569
[TBL] [Abstract][Full Text] [Related]
4. Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.
Khan H; Killoran RC; Brickenden A; Fan J; Yang D; Choy WY
Biochem J; 2015 Apr; 467(1):141-51. PubMed ID: 25582950
[TBL] [Abstract][Full Text] [Related]
5. Structural analysis of the complex of Keap1 with a prothymosin alpha peptide.
Padmanabhan B; Nakamura Y; Yokoyama S
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2008 Apr; 64(Pt 4):233-8. PubMed ID: 18391415
[TBL] [Abstract][Full Text] [Related]
6. Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes.
Karapetian RN; Evstafieva AG; Abaeva IS; Chichkova NV; Filonov GS; Rubtsov YP; Sukhacheva EA; Melnikov SV; Schneider U; Wanker EE; Vartapetian AB
Mol Cell Biol; 2005 Feb; 25(3):1089-99. PubMed ID: 15657435
[TBL] [Abstract][Full Text] [Related]
7. Binding of Disordered Peptides to Kelch: Insights from Enhanced Sampling Simulations.
Do TN; Choy WY; Karttunen M
J Chem Theory Comput; 2016 Jan; 12(1):395-404. PubMed ID: 26636721
[TBL] [Abstract][Full Text] [Related]
8. ¹H, ¹⁵N and ¹³C backbone resonance assignments of the Kelch domain of mouse Keap1.
Cino E; Fan J; Yang D; Choy WY
Biomol NMR Assign; 2013 Oct; 7(2):149-53. PubMed ID: 22688683
[TBL] [Abstract][Full Text] [Related]
9. Prothymosin α plays multifunctional cell robustness roles in genomic, epigenetic, and nongenomic mechanisms.
Ueda H; Matsunaga H; Halder SK
Ann N Y Acad Sci; 2012 Oct; 1269():34-43. PubMed ID: 23045968
[TBL] [Abstract][Full Text] [Related]
10. Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis.
Stępkowski TM; Kruszewski MK
Free Radic Biol Med; 2011 May; 50(9):1186-95. PubMed ID: 21295136
[TBL] [Abstract][Full Text] [Related]
11. Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling.
Lo SC; Li X; Henzl MT; Beamer LJ; Hannink M
EMBO J; 2006 Aug; 25(15):3605-17. PubMed ID: 16888629
[TBL] [Abstract][Full Text] [Related]
12. Effects of zinc binding on the structure and dynamics of the intrinsically disordered protein prothymosin alpha: evidence for metalation as an entropic switch.
Yi S; Boys BL; Brickenden A; Konermann L; Choy WY
Biochemistry; 2007 Nov; 46(45):13120-30. PubMed ID: 17929838
[TBL] [Abstract][Full Text] [Related]
13. Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction.
Hancock R; Bertrand HC; Tsujita T; Naz S; El-Bakry A; Laoruchupong J; Hayes JD; Wells G
Free Radic Biol Med; 2012 Jan; 52(2):444-51. PubMed ID: 22107959
[TBL] [Abstract][Full Text] [Related]
14. The Keap1-Nrf2 system as an in vivo sensor for electrophiles.
Uruno A; Motohashi H
Nitric Oxide; 2011 Aug; 25(2):153-60. PubMed ID: 21385624
[TBL] [Abstract][Full Text] [Related]
15. Identification and characterization of novel Nrf2 inducers designed to target the intervening region of Keap1.
Wu JH; Miao W; Hu LG; Batist G
Chem Biol Drug Des; 2010 May; 75(5):475-80. PubMed ID: 20486933
[TBL] [Abstract][Full Text] [Related]
16. Structural and Dynamic Characterization of Mutated Keap1 for Varied Affinity toward Nrf2: A Molecular Dynamics Simulation Study.
Cheng IC; Chen YJ; Ku CW; Huang YW; Yang CN
J Chem Inf Model; 2015 Oct; 55(10):2178-86. PubMed ID: 26348991
[TBL] [Abstract][Full Text] [Related]
17. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.
Niture SK; Jaiswal AK
J Biol Chem; 2009 May; 284(20):13856-13868. PubMed ID: 19279002
[TBL] [Abstract][Full Text] [Related]
18. Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).
Bresciani A; Missineo A; Gallo M; Cerretani M; Fezzardi P; Tomei L; Cicero DO; Altamura S; Santoprete A; Ingenito R; Bianchi E; Pacifici R; Dominguez C; Munoz-Sanjuan I; Harper S; Toledo-Sherman L; Park LC
Arch Biochem Biophys; 2017 Oct; 631():31-41. PubMed ID: 28801166
[TBL] [Abstract][Full Text] [Related]
19. Evidence for ProTα-TLR4/MD-2 binding: molecular dynamics and gravimetric assay studies.
Omotuyi O; Matsunaga H; Ueda H
Expert Opin Biol Ther; 2015; 15 Suppl 1():S223-9. PubMed ID: 25604147
[TBL] [Abstract][Full Text] [Related]
20. Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered.
Karunatilleke NC; Fast CS; Ngo V; Brickenden A; Duennwald ML; Konermann L; Choy WY
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34299054
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
