BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

389 related articles for article (PubMed ID: 23319586)

  • 1. In vivo cross-linking reveals principally oligomeric forms of α-synuclein and β-synuclein in neurons and non-neural cells.
    Dettmer U; Newman AJ; Luth ES; Bartels T; Selkoe D
    J Biol Chem; 2013 Mar; 288(9):6371-85. PubMed ID: 23319586
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defining the native state of α-synuclein.
    Selkoe D; Dettmer U; Luth E; Kim N; Newman A; Bartels T
    Neurodegener Dis; 2014; 13(2-3):114-7. PubMed ID: 24192542
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Purification of α-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity.
    Luth ES; Bartels T; Dettmer U; Kim NC; Selkoe DJ
    Biochemistry; 2015 Jan; 54(2):279-92. PubMed ID: 25490121
    [TBL] [Abstract][Full Text] [Related]  

  • 4. α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation.
    Bartels T; Choi JG; Selkoe DJ
    Nature; 2011 Aug; 477(7362):107-10. PubMed ID: 21841800
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 14-3-3 Proteins Reduce Cell-to-Cell Transfer and Propagation of Pathogenic α-Synuclein.
    Wang B; Underwood R; Kamath A; Britain C; McFerrin MB; McLean PJ; Volpicelli-Daley LA; Whitaker RH; Placzek WJ; Becker K; Ma J; Yacoubian TA
    J Neurosci; 2018 Sep; 38(38):8211-8232. PubMed ID: 30093536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
    Fauvet B; Mbefo MK; Fares MB; Desobry C; Michael S; Ardah MT; Tsika E; Coune P; Prudent M; Lion N; Eliezer D; Moore DJ; Schneider B; Aebischer P; El-Agnaf OM; Masliah E; Lashuel HA
    J Biol Chem; 2012 May; 287(19):15345-64. PubMed ID: 22315227
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A new method for quantitative immunoblotting of endogenous α-synuclein.
    Newman AJ; Selkoe D; Dettmer U
    PLoS One; 2013; 8(11):e81314. PubMed ID: 24278419
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein.
    Atieh TB; Roth J; Yang X; Hoop CL; Baum J
    Biomolecules; 2021 Oct; 11(10):. PubMed ID: 34680099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An α-synuclein decoy peptide prevents cytotoxic α-synuclein aggregation caused by fatty acid binding protein 3.
    Fukui N; Yamamoto H; Miyabe M; Aoyama Y; Hongo K; Mizobata T; Kawahata I; Yabuki Y; Shinoda Y; Fukunaga K; Kawata Y
    J Biol Chem; 2021; 296():100663. PubMed ID: 33862084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons.
    Wu Q; Takano H; Riddle DM; Trojanowski JQ; Coulter DA; Lee VM
    J Neurosci; 2019 Jun; 39(26):5080-5094. PubMed ID: 31036761
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of α-synuclein in vitro aggregation kinetics by its alternative splice isoforms.
    Röntgen A; Toprakcioglu Z; Tomkins JE; Vendruscolo M
    Proc Natl Acad Sci U S A; 2024 Feb; 121(7):e2313465121. PubMed ID: 38324572
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aβ exacerbates α-synuclein-induced neurotoxicity through impaired insulin signaling in α-synuclein-overexpressed human SK-N-MC neuronal cells.
    Chang CC; Li HH; Chang YT; Ho YJ; Hsieh LJ; Chiu PY; Cheng YS; Lin CL; Lai TJ
    CNS Neurosci Ther; 2018 Jan; 24(1):47-57. PubMed ID: 29092095
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Exploring the accessible conformations of N-terminal acetylated α-synuclein.
    Moriarty GM; Janowska MK; Kang L; Baum J
    FEBS Lett; 2013 Apr; 587(8):1128-38. PubMed ID: 23499431
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Parkinson-causing mutations in LRRK2 impair the physiological tetramerization of endogenous α-synuclein in human neurons.
    Fonseca-Ornelas L; Stricker JMS; Soriano-Cruz S; Weykopf B; Dettmer U; Muratore CR; Scherzer CR; Selkoe DJ
    NPJ Parkinsons Dis; 2022 Sep; 8(1):118. PubMed ID: 36114228
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxidative stress-induced posttranslational modifications of alpha-synuclein: specific modification of alpha-synuclein by 4-hydroxy-2-nonenal increases dopaminergic toxicity.
    Xiang W; Schlachetzki JC; Helling S; Bussmann JC; Berlinghof M; Schäffer TE; Marcus K; Winkler J; Klucken J; Becker CM
    Mol Cell Neurosci; 2013 May; 54():71-83. PubMed ID: 23369945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alpha-synuclein fragments trigger distinct aggregation pathways.
    Chakroun T; Evsyukov V; Nykänen NP; Höllerhage M; Schmidt A; Kamp F; Ruf VC; Wurst W; Rösler TW; Höglinger GU
    Cell Death Dis; 2020 Feb; 11(2):84. PubMed ID: 32015326
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Carboxy-terminal truncations of mouse α-synuclein alter aggregation and prion-like seeding.
    Sorrentino ZA; Xia Y; Gorion KM; Hass E; Giasson BI
    FEBS Lett; 2020 Apr; 594(8):1271-1283. PubMed ID: 31912891
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New insights into cellular α-synuclein homeostasis in health and disease.
    Dettmer U; Selkoe D; Bartels T
    Curr Opin Neurobiol; 2016 Feb; 36():15-22. PubMed ID: 26282834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss.
    Trudler D; Sanz-Blasco S; Eisele YS; Ghatak S; Bodhinathan K; Akhtar MW; Lynch WP; Piña-Crespo JC; Talantova M; Kelly JW; Lipton SA
    J Neurosci; 2021 Mar; 41(10):2264-2273. PubMed ID: 33483428
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration.
    Wang X; Becker K; Levine N; Zhang M; Lieberman AP; Moore DJ; Ma J
    Acta Neuropathol Commun; 2019 Mar; 7(1):41. PubMed ID: 30871620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.