These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

237 related articles for article (PubMed ID: 23322008)

  • 1. A novel inhibitor of STAT3 homodimerization selectively suppresses STAT3 activity and malignant transformation.
    Zhang X; Sun Y; Pireddu R; Yang H; Urlam MK; Lawrence HR; Guida WC; Lawrence NJ; Sebti SM
    Cancer Res; 2013 Mar; 73(6):1922-33. PubMed ID: 23322008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes.
    Zhang X; Yue P; Fletcher S; Zhao W; Gunning PT; Turkson J
    Biochem Pharmacol; 2010 May; 79(10):1398-409. PubMed ID: 20067773
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity.
    Siddiquee K; Zhang S; Guida WC; Blaskovich MA; Greedy B; Lawrence HR; Yip ML; Jove R; McLaughlin MM; Lawrence NJ; Sebti SM; Turkson J
    Proc Natl Acad Sci U S A; 2007 May; 104(18):7391-6. PubMed ID: 17463090
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An oxazole-based small-molecule Stat3 inhibitor modulates Stat3 stability and processing and induces antitumor cell effects.
    Siddiquee KA; Gunning PT; Glenn M; Katt WP; Zhang S; Schrock C; Sebti SM; Jove R; Hamilton AD; Turkson J
    ACS Chem Biol; 2007 Dec; 2(12):787-98. PubMed ID: 18154266
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel STAT3 Inhibitors Targeting STAT3 Dimerization by Binding to the STAT3 SH2 Domain.
    Hua Y; Yuan X; Shen YH; Wang J; Azeem W; Yang S; Gade A; Lellahi SM; Øyan AM; Ke X; Zhang WD; Kalland KH
    Front Pharmacol; 2022; 13():836724. PubMed ID: 35712699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cryptotanshinone inhibits constitutive signal transducer and activator of transcription 3 function through blocking the dimerization in DU145 prostate cancer cells.
    Shin DS; Kim HN; Shin KD; Yoon YJ; Kim SJ; Han DC; Kwon BM
    Cancer Res; 2009 Jan; 69(1):193-202. PubMed ID: 19118003
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Micellar nano-carriers for the delivery of STAT3 dimerization inhibitors to melanoma.
    Soleimani AH; Garg SM; Paiva IM; Vakili MR; Alshareef A; Huang YH; Molavi O; Lai R; Lavasanifar A
    Drug Deliv Transl Res; 2017 Aug; 7(4):571-581. PubMed ID: 28290050
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells.
    Lin L; Hutzen B; Li PK; Ball S; Zuo M; DeAngelis S; Foust E; Sobo M; Friedman L; Bhasin D; Cen L; Li C; Lin J
    Neoplasia; 2010 Jan; 12(1):39-50. PubMed ID: 20072652
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of STAT3 activity delays obesity-induced thyroid carcinogenesis in a mouse model.
    Park JW; Han CR; Zhao L; Willingham MC; Cheng SY
    Endocr Relat Cancer; 2016 Jan; 23(1):53-63. PubMed ID: 26552408
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A cell-permeable Stat3 SH2 domain mimetic inhibits Stat3 activation and induces antitumor cell effects in vitro.
    Zhao W; Jaganathan S; Turkson J
    J Biol Chem; 2010 Nov; 285(46):35855-65. PubMed ID: 20807764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stattic: a small-molecule inhibitor of STAT3 activation and dimerization.
    Schust J; Sperl B; Hollis A; Mayer TU; Berg T
    Chem Biol; 2006 Nov; 13(11):1235-42. PubMed ID: 17114005
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impact of STAT3 inhibition on survival of osteosarcoma cell lines.
    Wang X; Goldstein D; Crowe PJ; Yang JL
    Anticancer Res; 2014 Nov; 34(11):6537-45. PubMed ID: 25368256
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antagonism of the Stat3-Stat3 protein dimer with salicylic acid based small molecules.
    Fletcher S; Page BD; Zhang X; Yue P; Li ZH; Sharmeen S; Singh J; Zhao W; Schimmer AD; Trudel S; Turkson J; Gunning PT
    ChemMedChem; 2011 Aug; 6(8):1459-70. PubMed ID: 21618433
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel STAT3 inhibitor WZ-2-033 causes regression of human triple-negative breast cancer and gastric cancer xenografts.
    Zhong Y; Deng L; Shi S; Huang QY; Ou-Yang SM; Mo JS; Zhu K; Qu XM; Liu PQ; Wang YX; Zhang XL
    Acta Pharmacol Sin; 2022 Apr; 43(4):1013-1023. PubMed ID: 34267347
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A small molecule compound targeting STAT3 DNA-binding domain inhibits cancer cell proliferation, migration, and invasion.
    Huang W; Dong Z; Wang F; Peng H; Liu JY; Zhang JT
    ACS Chem Biol; 2014 May; 9(5):1188-96. PubMed ID: 24661007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation.
    Turkson J; Ryan D; Kim JS; Zhang Y; Chen Z; Haura E; Laudano A; Sebti S; Hamilton AD; Jove R
    J Biol Chem; 2001 Nov; 276(48):45443-55. PubMed ID: 11579100
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent.
    Ball DP; Lewis AM; Williams D; Resetca D; Wilson DJ; Gunning PT
    Oncotarget; 2016 Apr; 7(15):20669-79. PubMed ID: 26942696
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy.
    Pang M; Ma L; Gong R; Tolbert E; Mao H; Ponnusamy M; Chin YE; Yan H; Dworkin LD; Zhuang S
    Kidney Int; 2010 Aug; 78(3):257-68. PubMed ID: 20520592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Therapeutic Effects of STAT3 Inhibition on Experimental Murine Dry Eye.
    Qu M; Qi X; Wang Q; Wan L; Li J; Li W; Li Y; Zhou Q
    Invest Ophthalmol Vis Sci; 2019 Sep; 60(12):3776-3785. PubMed ID: 31503282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of quantitative assays for the identification of direct signal transducer and activator of transcription 3 (STAT3) inhibitors.
    Furtek SL; Matheson CJ; Backos DS; Reigan P
    Oncotarget; 2016 Nov; 7(47):77998-78008. PubMed ID: 27793003
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.