402 related articles for article (PubMed ID: 23325245)
1. Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain.
Abrahamsen B; Schneider N; Erichsen MN; Huynh TH; Fahlke C; Bunch L; Jensen AA
J Neurosci; 2013 Jan; 33(3):1068-87. PubMed ID: 23325245
[TBL] [Abstract][Full Text] [Related]
2. Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4.
Abousaab A; Warsi J; Elvira B; Lang F
J Membr Biol; 2016 Jun; 249(3):239-49. PubMed ID: 26690923
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102.
Huynh TH; Abrahamsen B; Madsen KK; Gonzalez-Franquesa A; Jensen AA; Bunch L
Bioorg Med Chem; 2012 Dec; 20(23):6831-9. PubMed ID: 23072958
[TBL] [Abstract][Full Text] [Related]
4. Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH-102.
Haym I; Huynh TH; Hansen SW; Pedersen MH; Ruiz JA; Erichsen MN; Gynther M; Bjørn-Yoshimoto WE; Abrahamsen B; Bastlund JF; Bundgaard C; Eriksen AL; Jensen AA; Bunch L
ChemMedChem; 2016 Feb; 11(4):403-19. PubMed ID: 26797816
[TBL] [Abstract][Full Text] [Related]
5. Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs.
Erichsen MN; Hansen J; Ruiz JA; Demmer CS; Abrahamsen B; Bastlund JF; Bundgaard C; Jensen AA; Bunch L
Neurochem Res; 2014 Oct; 39(10):1964-79. PubMed ID: 24682739
[TBL] [Abstract][Full Text] [Related]
6. Hetero-oligomerization of neuronal glutamate transporters.
Nothmann D; Leinenweber A; Torres-Salazar D; Kovermann P; Hotzy J; Gameiro A; Grewer C; Fahlke C
J Biol Chem; 2011 Feb; 286(5):3935-43. PubMed ID: 21127051
[TBL] [Abstract][Full Text] [Related]
7. Conserved allosteric inhibition mechanism in SLC1 transporters.
Dong Y; Wang J; Garibsingh RA; Hutchinson K; Shi Y; Eisenberg G; Yu X; Schlessinger A; Grewer C
Elife; 2023 Mar; 12():. PubMed ID: 36856089
[TBL] [Abstract][Full Text] [Related]
8. New Insight into the Structure-Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors UCPH-101 and UCPH-102.
Hansen SW; Erichsen MN; Huynh TH; Ruiz JA; Haym I; Bjørn-Yoshimoto WE; Abrahamsen B; Hansen J; Storgaard M; Eriksen AL; Jensen AA; Bunch L
ChemMedChem; 2016 Feb; 11(4):382-402. PubMed ID: 26757239
[TBL] [Abstract][Full Text] [Related]
9. Structure-activity relationship study of selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101) and absolute configurational assignment using infrared and vibrational circular dichroism spectroscopy in combination with ab initio Hartree-Fock calculations.
Huynh TH; Shim I; Bohr H; Abrahamsen B; Nielsen B; Jensen AA; Bunch L
J Med Chem; 2012 Jun; 55(11):5403-12. PubMed ID: 22594609
[TBL] [Abstract][Full Text] [Related]
10. The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings.
Suchak SK; Baloyianni NV; Perkinton MS; Williams RJ; Meldrum BS; Rattray M
J Neurochem; 2003 Feb; 84(3):522-32. PubMed ID: 12558972
[TBL] [Abstract][Full Text] [Related]
11. Neuronal glutamate transporters vary in substrate transport rate but not in unitary anion channel conductance.
Torres-Salazar D; Fahlke C
J Biol Chem; 2007 Nov; 282(48):34719-26. PubMed ID: 17908688
[TBL] [Abstract][Full Text] [Related]
12. Excitatory amino acid transporter expression by astrocytes is neuroprotective against microglial excitotoxicity.
Liang J; Takeuchi H; Doi Y; Kawanokuchi J; Sonobe Y; Jin S; Yawata I; Li H; Yasuoka S; Mizuno T; Suzumura A
Brain Res; 2008 May; 1210():11-9. PubMed ID: 18410911
[TBL] [Abstract][Full Text] [Related]
13. Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1.
Jensen AA; Erichsen MN; Nielsen CW; Stensbøl TB; Kehler J; Bunch L
J Med Chem; 2009 Feb; 52(4):912-5. PubMed ID: 19161278
[TBL] [Abstract][Full Text] [Related]
14. Regulation of the glutamate transporters by JAK2.
Hosseinzadeh Z; Bhavsar SK; Sopjani M; Alesutan I; Saxena A; Dërmaku-Sopjani M; Lang F
Cell Physiol Biochem; 2011; 28(4):693-702. PubMed ID: 22178881
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101).
Erichsen MN; Huynh TH; Abrahamsen B; Bastlund JF; Bundgaard C; Monrad O; Bekker-Jensen A; Nielsen CW; Frydenvang K; Jensen AA; Bunch L
J Med Chem; 2010 Oct; 53(19):7180-91. PubMed ID: 20857912
[TBL] [Abstract][Full Text] [Related]
16. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins.
Jackson M; Song W; Liu MY; Jin L; Dykes-Hoberg M; Lin CI; Bowers WJ; Federoff HJ; Sternweis PC; Rothstein JD
Nature; 2001 Mar; 410(6824):89-93. PubMed ID: 11242047
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological characterization of threo-3-methylglutamic acid with excitatory amino acid transporters in native and recombinant systems.
Eliasof S; McIlvain HB; Petroski RE; Foster AC; Dunlop J
J Neurochem; 2001 Apr; 77(2):550-7. PubMed ID: 11299317
[TBL] [Abstract][Full Text] [Related]
18. The glutamate transporter EAAT4 in rat cerebellar Purkinje cells: a glutamate-gated chloride channel concentrated near the synapse in parts of the dendritic membrane facing astroglia.
Dehnes Y; Chaudhry FA; Ullensvang K; Lehre KP; Storm-Mathisen J; Danbolt NC
J Neurosci; 1998 May; 18(10):3606-19. PubMed ID: 9570792
[TBL] [Abstract][Full Text] [Related]
19. Reduced expression of glutamate transporters vGluT1, EAAT2 and EAAT4 in learned helpless rats, an animal model of depression.
Zink M; Vollmayr B; Gebicke-Haerter PJ; Henn FA
Neuropharmacology; 2010 Feb; 58(2):465-73. PubMed ID: 19747495
[TBL] [Abstract][Full Text] [Related]
20. Characterization of novel L-threo-beta-benzyloxyaspartate derivatives, potent blockers of the glutamate transporters.
Shimamoto K; Sakai R; Takaoka K; Yumoto N; Nakajima T; Amara SG; Shigeri Y
Mol Pharmacol; 2004 Apr; 65(4):1008-15. PubMed ID: 15044631
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]